What Percentage of Body Weight Have You Lost?

51, F, 5'4", SW 190, CW 143 so a little over 25%. I started compounded Tirz in October and have not yet gone above 5mg. My first goal was 150 but I passed that, now I'm not sure what my next goal will be. Getting into the 130's would be nice, but I'm over the moon happy with where I have gotten this far. I never even dreamed this weight, and level of health, was possible for me!
 
40% 280 --> 169, 43 weeks As of about 30 minutes ago officially Normal BMI of 24.9, 5' 9" 46M.


Tirz and then added small doses of survo at around week 30 3.5 days after tirz to help with appetite supression. 15mg tirz for 20 weeks so far and consistently loosing 2.5lbs a week
 
tangoecho311 said:
30%. Started August 2025 at 225, now I'm at 155 and switched to maintenance. My surgeon estimates he will remove 10lbs of skin. That will bump it up to 35% loss.
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Wow, congratulations! Yeah, the ecstasy of losing weight is tempered by the reality of what maintenance looks like. I'm almost at maintenance. I have a plan, but it is subject to change. I'm down 98lbs but I don't think I will have skin removal. I don't have folds of skin, but the crinkled orange peel effect sure doesn't look good. Whatever. I'm doing this for health, not vanity. Not having high blood pressure, diabetes, fatty liver, etc., etc., is much better than the alternative. I'm grateful for what I have achieved. Oh, and by the way, I am now down 40%.
 
m100568 said:
I was looking at the mouse study on Retatrutide and cancer. https://www.nature.com/articles/s44324-025-00054-5 The cancer implications are very interesting on its own, but that is not the purpose of this post. The other thing that caught my eye in the study is that the mice lost 40% to 41% of body weight and stabilized there. We have the Phase II data of 24.2%, but people were still losing weight after 48 weeks. There is no published data on when it plateaus. EL has extended the studies, so it looks like they are trying to find that out.

I have been stacking Tirz and Reta for 8 1/2 months. I have lost 35% of my body weight and I am still losing. I would like to get down to 40% to reach my ideal weight. My question is for people on maintenance or close to maintenance; what percentage of your body weight have you lost? Has anyone hit 40%, or more?
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I have lost 43% of my body weight. I have been maintaining for over a year now. Tirz 100% of the time. I have stacked Sema and Cagri. A few months on one then a few months on the other. Just to switch things up.
 
6.9% (1.7 lb/week) in 8 weeks with 2 mg reta weekly. My goal is 15-17%. I have no idea what I will do for maintenance, though.

I will stick with this low dose until it stops working. I guess I could be losing weight more quickly, but I am having zero side effects and 2 mg reta is cheap. I eat and drink whatever I want, I just want less. This is as easy as falling off a log.
 
Calm Logic said:
Since starting five weeks ago: 7 percent (3.4 pounds per week, 17 pounds total: 241 pounds to 224).

Dosing: Went up 2.5 mg weekly to 10 mg of tirz, as suggested by my internist.
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17 lbs in 5 weeks--that's so great! I know this is older, but still. Where are you at now?
 
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