When will we get grey eloralintide

m100568

GLP-1 Apprentice
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Phase II eloralintide results just came out after 48 weeks. They match tirzepatide. The grey market typically starts producing after Phase II. So, when can we start buying grey eloralintide? I think it would make an amazing stack. Lilly is already testing it with tirzepatide.

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The little i have read so far is that it only seems to supresse apetite, just as Tirza.
If thats how it works i think Reta still will be the best GLP product.
But i have not read enough about yet to be some kind of expert.
If there is anyonelse who have a more detailed picture of it. Please share it here 😊
 
Tirz-Elora may end up being EL's competitor to Cagri-Sema. The combo of tirzepatide and eloralintide would be a triple agonist, very curious how it would stack up against retatrutide in trials.
 
The little i have read so far is that it only seems to supresse apetite, just as Tirza.
If thats how it works i think Reta still will be the best GLP product.
But i have not read enough about yet to be some kind of expert.
If there is anyonelse who have a more detailed picture of it. Please share it here 😊
elora is not a glpra so it could most likely complement reta even better than it does tirz
 
The little i have read so far is that it only seems to supresse apetite, just as Tirza.
If thats how it works i think Reta still will be the best GLP product.
But i have not read enough about yet to be some kind of expert.
If there is anyonelse who have a more detailed picture of it. Please share it here 😊
I was in the trial. It works on food noise, slows gastric emptying, suppresses appetite. For me, it also decreased inflammation and improved my sleep.
 
I was in the trial. It works on food noise, slows gastric emptying, suppresses appetite. For me, it also decreased inflammation and improved my sleep.
Oh cool! I was in a CagriSema trial (as the tirzepatide comparison though). Can you tell us what your protocol was? Dose schedule and generally what kind of tests and whatnot?

Mine's here.
 
Oh cool! I was in a CagriSema trial (as the tirzepatide comparison though). Can you tell us what your protocol was? Dose schedule and generally what kind of tests and whatnot?

Mine's here.
I started at 9 mg and stayed there the whole time. I had 3 dexascans, multiple ekgs and lots of blood work. I had to wear a fitness tracker for 2 weeks at 3 different times.
 
The little i have read so far is that it only seems to supresse apetite, just as Tirza.
If thats how it works i think Reta still will be the best GLP product.
But i have not read enough about yet to be some kind of expert.
If there is anyonelse who have a more detailed picture of it. Please share it here 😊
I think Reta is also the most effective one because it is the most popular
 
Tirz-Elora may end up being EL's competitor to Cagri-Sema. The combo of tirzepatide and eloralintide would be a triple agonist, very curious how it would stack up against retatrutide in trials.
As a triple agonist, Tirz-Elora (tielpolin + elolarinpeptide) may become Eli Lilly's competitor to Cagri-Sema.

Compared with retalutide:

1. Different mechanisms: The former targets GLP-1, GIP and amylin receptors, focusing on enhancing appetite suppression; The latter, with the additional effect of glucagon receptors, may be more conducive to fat burning.

2. Effect to be determined: Both may have a strong effect on weight loss, but the early data of retalutide is more prominent.
 
As a triple agonist, Tirz-Elora (tielpolin + elolarinpeptide) may become Eli Lilly's competitor to Cagri-Sema.

Compared with retalutide:

1. Different mechanisms: The former targets GLP-1, GIP and amylin receptors, focusing on enhancing appetite suppression; The latter, with the additional effect of glucagon receptors, may be more conducive to fat burning.

2. Effect to be determined: Both may have a strong effect on weight loss, but the early data of retalutide is more prominent.

as it stands reta seems to be a bit more effective than tirz, and once elora and reta are out, there's no apparent reason they couldn't combine them

tirz and elora also seem to have the same primary effect (reducing food noise/appetite) whereas reta is considered the weakest at that despite apparently being the most effective overall for weight loss

in my opinion, this reasons out to reta+elora being the most effective combination therapy in the next few years, as the elora complements reta perfectly in fixing its only apparent weakness while both being approximately the best in their class
 
as it stands reta seems to be a bit more effective than tirz, and once elora and reta are out, there's no apparent reason they couldn't combine them

tirz and elora also seem to have the same primary effect (reducing food noise/appetite) whereas reta is considered the weakest at that despite apparently being the most effective overall for weight loss

in my opinion, this reasons out to reta+elora being the most effective combination therapy in the next few years, as the elora complements reta perfectly in fixing its only apparent weakness while both being approximately the best in their class
wouldn't reta + cagri be the same ? What receptors does elora hit ?
 
wouldn't reta + cagri be the same ? What receptors does elora hit ?
similar, yes, but eloralintide seems to be more effective. they're both amylin receptor agonists.

reta and elora are also made by the same company unlike cagri, so it's likely it can/will be prescribed as an official combination therapy in the next several years. obviously less relevant for gray market using experimenters, but more relevant from a public health perspective.
 

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