WSJ, Lilly’s First Pill for Diabetes, Weight Loss Shows Positive Study Results: The drug helped lower blood sugar and cut an average of 16 pounds

[keangkong]

WSJ, Lilly’s First Pill for Diabetes, Weight Loss Shows Positive Study Results: The drug helped lower blood sugar and cut an average of 16 pounds, unlocked article.

https://www.wsj.com/health/pharma/l...7?st=JqZu1h&reflink=desktopwebshare_permalink

 

[Peptidase]

I can see how this would be helpful for maintenance but they just seem to be a lot less effective than the injectables. 7.9% weight loss at 40 weeks (highest dose) is kind of a tough sell given the results with the others. Although this is associated with no plateaus. Wonder what this will look like at 68-72 weeks.

 

[keangkong]

WSJ, Lilly’s First Pill for Diabetes, Weight Loss Shows Positive Study Results: The drug helped lower blood sugar and cut an average of 16 pounds, unlocked article.

https://www.wsj.com/health/pharma/l...7?st=JqZu1h&reflink=desktopwebshare_permalink

Or for Eli Lilly' take, read its press release: Lilly's oral GLP-1, orforglipron, demonstrated statistically significant efficacy results and a safety profile consistent with injectable GLP-1 medicines in successful Phase 3 trial

 

[keangkong]

I can see how this would be helpful for maintenance but they just seem to be a lot less effective than the injectables. 7.9% weight loss at 40 weeks (highest dose) is kind of a tough sell given the results with the others. Although this is associated with no plateaus. Wonder what this will look like at 68-72 weeks.

I wouldn't switch to orforglipron, however many folks likely avoid GLP-1 drugs due to a desire to avoid injecting themselves. Perhaps this drug will be more affordable than the good weight loss drugs now out there.

 

[FrankTdog]

I wouldn't switch, because *for me* a once a week shot is easier than a daily pill. But for a lot of people this is a great alternative.