Liraglutide from Grey

[druell235]

Is it possible to get liraglutide from grey vendors. I know its not nearly as effective from a results standpoint, but just curious.

 

[Labcat]

Is it possible to get liraglutide from grey vendors. I know its not nearly as effective from a results standpoint, but just curious.

I saw it was listed on HPT

What have you heard about it not veing as effective?
Are you using brand name currently? I was prescribed it and looking for options too.

 

[miss-sanne]

liraglutide is only 5-8 % weightloss, so much less effective for that.
Also, effect on appetite varies during the day because of the short halflife.
but it's not a bad drug, it does work.

 

[Labcat]

liraglutide is only 5-8 % weightloss, so much less effective for that.
Also, effect on appetite varies during the day because of the short halflife.
but it's not a bad drug, it does work.

Ah, I misinterpreted OP as saying gray lira is worse! And was surprised 🙂

 

[miss-sanne]

Ah, I misinterpreted OP as saying gray lira is worse! And was surprised 🙂

Labcat, your user name says it, but I always misinterpret your pic. lol.
Yes I have presbyopia. But I'm still not sure if it IS a cat or ??

 

[Labcat]

Labcat, your user name says it, but I always misinterpret your pic. lol.
Yes I have presbyopia. But I'm still not sure if it IS a cat or ??

Yes, that is my extra long orange tabby looking extra extra long stretched out on the couch, looking out the window.

Now I’m a little afraid to ask… but no pain no gain… what does it look like 🤣?

 

[miss-sanne]

Yes, that is my extra long orange tabby looking extra extra long stretched out on the couch, looking out the window.

Now I’m a little afraid to ask… but no pain no gain… what does it look like 🤣?

That's a cute one !
I'm not sure, it's a bit of a blur, but my thoughts weren't entirely pure, I have to admit. lol

 

[Labcat]

That's a cute one !
I'm not sure, it's a bit of a blur, but my thoughts weren't entirely pure, I have to admit. lol

🤣

 

[miss-sanne]

🤣

First time I saw it, had to zoom in to make sure it was a lab cat lol

 

[Labcat]

First time I saw it, had to zoom in to make sure it was a lab cat lol

Well, he is more of a lap cat.

 

[Calm Logic]

Comparing lira vs. sema vs. orfo:

https://www.nejm.org/doi/full/10.1056/nejmoa2302392

Phase 3 trials of liraglutide (the SCALE trial4) and semaglutide (the STEP 1 trial5) showed significant weight reduction at 56 weeks and 68 weeks, respectively, with a mean reduction of 9.2% with liraglutide and 16.9% with semaglutide. This phase 2 trial of orforglipron showed weight reduction ranging from 8.6% to 12.6% at 26 weeks and ranging from 9.4% to 14.7% at 36 weeks.

Table of the above:

Medication	Trial Phase	Duration	Weight Reduction
Liraglutide	Phase 3	56 Weeks	9.2%
Semaglutide	Phase 3	68 Weeks	16.9%
Orforglipron	Phase 2	36 Weeks	9.4% – 14.7%

But there is always a subset of people in those trials who lose way more than that. My impression from the trials is that lira tends to "poop out" earlier than the other GLPS except for maintenance.