Anyone with tesamorelin experience?

According to WebMD, even HGH usually only results in a small amount of fat loss:

www.webmd.com

The Truth About HGH for Weight Loss

The quest for a weight loss solution has some people taking human growth hormone (HGH) in pills, powders and injections. But does it really work?
www.webmd.com www.webmd.com

When adults with an HGH deficiency resulting from pituitary disease are given HGH replacement, it improves body composition -- increasing bone mass and muscle mass and decreasing fat stores.

But it does not cause weight loss in the obese, says Nicholas Tritos, MD, who co-authored an analysis evaluating the effectiveness of HGH for weight loss in obese people.

"Our results showed small improvements in body composition, a small reduction in body fat and increase in muscle mass, but on balance, weight did not change," he says. "More notable changes are seen when an individual is deficient in growth hormone from true pituitary disease."

Another study found that HGH therapy was linked to a small decrease in fat and increase in lean mass, but no change in body weight. The researchers concluded that HGH is not an effective treatment in obese people, and said more studies were needed.

Further, the American Association of Clinical Endocrinologists has warned that the use of HGH for obese patients is not recommended.
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I'm only 3 days into taking tesa/ipa/cjc. Today, I was poking through some of my health tracking numbers and noticed that beginning with the first dose, my HRV (heart rate variability) more than doubled. I've been pretty much stuck at an HRV around 45 since I first started tracking it about 4 years ago. Now it's running 85 to 116. That's an unexpected positive change.

I've also been sleeping better the last 3 nights.
 
HumanusExMachina said:
I'm only 3 days into taking tesa/ipa/cjc. Today, I was poking through some of my health tracking numbers and noticed that beginning with the first dose, my HRV (heart rate variability) more than doubled. I've been pretty much stuck at an HRV around 45 since I first started tracking it about 4 years ago. Now it's running 85 to 116. That's an unexpected positive change.

I've also been sleeping better the last 3 nights.
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I've been on it for a month now and sleep quality has most definitely improved by both my personal opinion and my watch tracking my sleep. Routinely getting a 99 sleep score.
 
HumanusExMachina said:
I'm only 3 days into taking tesa/ipa/cjc. Today, I was poking through some of my health tracking numbers and noticed that beginning with the first dose, my HRV (heart rate variability) more than doubled. I've been pretty much stuck at an HRV around 45 since I first started tracking it about 4 years ago. Now it's running 85 to 116. That's an unexpected positive change.

I've also been sleeping better the last 3 nights.
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How long did you do the protocol, and what were your findings?
 
I'm a week on so far. Starting with 1mg a day before bed for the first 10 days then going to bump it up to 2mg for another 5 days before adding in IPA at 250mcg morning and night. So far I haven't noticed much in the water retention but I'm sure it's coming when I jump to 2mg. I don't really care about the water weight though. After it caps out and I start losing again, dropping it at the end of the cycle will be a little bonus to look forward to. I do get little stinging and some itchiness at the injection site as I go to bed, but it's always gone when I wake up. And my sleep has been improving. I'm really optimistic about this stack and am looking forward to seeing some results.
 
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Calm Logic said:
I would go to 1.5 mg before upping to 2 mg. Haven't tried tesa yet, but a buddy of mine had carpal tunnel quickly after going from 1 mg to 2 mg.
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That's the last thing I need right now. I'm currently treating a bad tennis elbow flair up. Damn thing keeps popping up every few months for the last couple years. I'll definitely titrate up slower. Thanks for the heads up.
 
Tbagger said:
I'm a week on so far. Starting with 1mg a day before bed for the first 10 days then going to bump it up to 2mg for another 5 days before adding in IPA at 250mcg morning and night. So far I haven't noticed much in the water retention but I'm sure it's coming when I jump to 2mg. I don't really care about the water weight though. After it caps out and I start losing again, dropping it at the end of the cycle will be a little bonus to look forward to. I do get little stinging and some itchiness at the injection site as I go to bed, but it's always gone when I wake up. And my sleep has been improving. I'm really optimistic about this stack and am looking forward to seeing some results.
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Thanks for sharing this. I plan on running it in a few weeks. I know everyone responds differently but this was a reassuring read.
 
Tbagger said:
I'm a week on so far. Starting with 1mg a day before bed for the first 10 days then going to bump it up to 2mg for another 5 days before adding in IPA at 250mcg morning and night. So far I haven't noticed much in the water retention but I'm sure it's coming when I jump to 2mg. I don't really care about the water weight though. After it caps out and I start losing again, dropping it at the end of the cycle will be a little bonus to look forward to. I do get little stinging and some itchiness at the injection site as I go to bed, but it's always gone when I wake up. And my sleep has been improving. I'm really optimistic about this stack and am looking forward to seeing some results.
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A few tips I've collected regarding managing water weight:

Calm Logic said:
As with HGH, the water retention may be managed by 5 days on, 2 days off, along with staying hydrated and taking more taurine, potassium, and magnesium (to reduce the sodium-based water pressure pushing on the nerves).

"Take 5g of taurine a day when using GH, to prevent/lessen [carpal tunnel syndrome]."

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Not to change the subject but I wonder how Kisspeptin would compare to the GHRH/GHRPs. It doesn’t mess with HGH yet raises testosterone through LH and FSH stimulation. Might Kisspeptin do much of the same without the tumor promoting fears that excessive HGH and GHRHs bring?
 
Jellybelly54 said:
Not to change the subject but I wonder how Kisspeptin would compare to the GHRH/GHRPs. It doesn’t mess with HGH yet raises testosterone through LH and FSH stimulation. Might Kisspeptin do much of the same without the tumor promoting fears that excessive HGH and GHRHs bring?
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Kisspeptin-10 reliably raises LH and sometimes FSH, but definitely not enough to raise testosterone. You would have to inject roughly every 2 or 3 hours to hope to see a rise in testosterone levels.
 
For those with concerns about safety, a safer alternative to tesa and the others is sermorelin, a cheaper, longer-term option. But it is also less effective except for anti-aging or general wellness.

Just saw this today, playing with Google Gemini: "Heavy squats, sprints, and 8 hours of blackout-curtain sleep will produce massive GH pulses for free."
 
Mr. Blonde said:
I got a kit of tesamorelin and can't wait to start pinning. Hopefully, I get the sleep benefits that others rave about. I did cjc1295/ipa in the past for 8weeks and it wrecked my sleep from night 1.
Fingers crossed
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Can I ask how the Ipa wrecked your sleep and whether the Tesa has helped? I've been taking GHRP-2/Sermorelin and have noticed much deeper sleep although still waking up every few hours, have been thinking of switching to Ipa/Tesa stack or something similar but the sleep benefits are an important aspect to me, in fact would most likely end up sticking with whatever stack allows for the longest/most restful sleep lol
 
ftv10hb said:
Can I ask how the Ipa wrecked your sleep and whether the Tesa has helped? I've been taking GHRP-2/Sermorelin and have noticed much deeper sleep although still waking up every few hours, have been thinking of switching to Ipa/Tesa stack or something similar but the sleep benefits are an important aspect to me, in fact would most likely end up sticking with whatever stack allows for the longest/most restful sleep lol
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I never used them separately. I always pinned each one at night before bed. From night one my sleep suffered. This apparently only happens to a small percentage of people.
 
Mr. Blonde said:
I never used them separately. I always pinned each one at night before bed. From night one my sleep suffered. This apparently only happens to a small percentage of people.
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Ok got it, yea I will be taking together as well, if that's a rarer effect than will just keep fingers crossed I guess lol
 
Just finished a Kisspeptin and Tesamorelin cycle 7weeks of kiss in the am and tesa 1mg in the pm. Well, my free and total T went down not up! I felt no change on either pep. Did not notice any belly fat loss and my weight stayed exactly the same as did my body fat! What to do now? Get on gear? Up the dose of tesa? Switch to CJC ? My free testosterone as well as total testosterone actually went up while I was on IPAMORELIN prior to the tesa cycle so was expecting more positive changes than what I got. I also checked IGF-1 and GH levels and they were completely normal. GH was actually low at 0.2 but was a 10:30 am blood draw so expected to be low of at least not elevate .
 
Jellybelly54 said:
Just finished a Kisspeptin and Tesamorelin cycle 7weeks of kiss in the am and tesa 1mg in the pm. Well, my free and total T went down not up! I felt no change on either pep. Did not notice any belly fat loss and my weight stayed exactly the same as did my body fat! What to do now? Get on gear? Up the dose of tesa? Switch to CJC ? My free testosterone as well as total testosterone actually went up while I was on IPAMORELIN prior to the tesa cycle so was expecting more positive changes than what I got. I also checked IGF-1 and GH levels and they were completely normal. GH was actually low at 0.2 but was a 10:30 am blood draw so expected to be low of at least not elevate .
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I have seen at least one or two other posts where people said Ipa increased their testosterone levels, and seem to be a few people who have said Kisspeptin didn't seem to do much for them at all. Wondering if there are more out there who can confirm the test effects of Ipa, or who have had different experience with Kisspeptin? Have been interested in both but if the side benefit of Ipa is actually better than the intended benefit of Kisspeptin then probably would be the end of my interest in Kisspeptin lol
 
ftv10hb said:
I have seen at least one or two other posts where people said Ipa increased their testosterone levels, and seem to be a few people who have said Kisspeptin didn't seem to do much for them at all. Wondering if there are more out there who can confirm the test effects of Ipa, or who have had different experience with Kisspeptin? Have been interested in both but if the side benefit of Ipa is actually better than the intended benefit of Kisspeptin then probably would be the end of my interest in Kisspeptin lol
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Just goes to show when doing research testing is imperative . I was only doing 7.5 units of Kiss once a day as I read overstimulating with too much will shut things down. I expected my LH and FSH to be elevated after the cycle as well but those were low normal. I don’t know? Thinking about taking this low free T result to the low T clinic and start some T and see if it makes me feel different/better/worse? I may try TESTAGEN next ?
 
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Tbagger said:
That's the last thing I need right now. I'm currently treating a bad tennis elbow flair up. Damn thing keeps popping up every few months for the last couple years. I'll definitely titrate up slower. Thanks for the heads up.
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Curious how you are treating the tennis elbow? I get it every once in awhile as well, I haven't started looking yet into the healing/regenerative type peptides that might help with it
 
How is that working out so far? Cartalax I've heard of, ARA290 I haven't.
 
ftv10hb said:
Curious how you are treating the tennis elbow? I get it every once in awhile as well, I haven't started looking yet into the healing/regenerative type peptides that might help with it
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I am taking .25mg box twice a day in my tricep. I’m also taking 2mg GHK and .5mg KPV once a day along with 2mg tb500 every other day. And I have Cartalax on order and am just waiting for it to come in.
 
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