Dosing schedule

I just pin one 1 mg per week. I've seen a lot of people, such as yourself, do every x amount of mg per days, like every two days or every three days. Does that make any difference? For me, that 1mg, it does pretty well for me. I don't experience anything that I would need to re-pin again in the same week, but I think everyone's different.
So I use it purely for appetite control. There's a myth that dosing once weekly keeps receptors sensitive, and that's not true at all. You can dose every 3, 5, or 7 days as you feel comfortable. The half life is six days. I think if I wasn't worried about appetite control, I would probably be dosing every five or six days just to keep blood levels steadier.

But yeah, the big benefit to dosing every 3 days is appetite suppression. I become incredibly hungry 4 or 5 days after dosing. Since going up to 4.6mg per week, I've actually found the hunger even harder to deal with. I think it's mostly a discipline and lifestyle issue on my part, and a desire to sustain 3lbs/wk losses minimum, but it really does make me consider adding cagri or tirz to the mix.
 
The melatonin has quite the effect on me. I take it in gummy form. About 10 minutes after I take it, I'm asleep, unless I'm on my phone or have the TV on, of course. It's also a powerful anti-oxidant to boot. I also put on some rain sounds to cue for my brain that it's time to sleep. Quality of sleep has become so precious to me so I have black out curtains, I've learned the less light in the room the better your quality of sleep.
Yeah, I do exactly that. Pitch black room and there's a noise machine. I also make sure the room is pretty cold as well. So I fall asleep pretty fast since I'm tired from my early morning workout and then the fatigue catches up to me near my bedtime. My only issue is that I keep getting up to use the bathroom lol i gotta stop drinking too much water! But I cant because reta makes me so dehydrated so im just spamming water all day.😤 . Are yall experiencing the dehydration as well?
 
So I use it purely for appetite control. There's a myth that dosing once weekly keeps receptors sensitive, and that's not true at all. You can dose every 3, 5, or 7 days as you feel comfortable. The half life is six days. I think if I wasn't worried about appetite control, I would probably be dosing every five or six days just to keep blood levels steadier.

But yeah, the big benefit to dosing every 3 days is appetite suppression. I become incredibly hungry 4 or 5 days after dosing. Since going up to 4.6mg per week, I've actually found the hunger even harder to deal with. I think it's mostly a discipline and lifestyle issue on my part, and a desire to sustain 3lbs/wk losses minimum, but it really does make me consider adding cagri or tirz to the mix.
Oh wow, that's a pretty aggressive weight loss schedule. Right now, I'm at about 1.5 to 2 pounds a week. Sometimes it goes to 1 pound a week, but it's slowing down now because I'm getting a bit too lean. It is pretty crazy, though, how you're experiencing appetite go up quite a bit because I haven't felt hunger since like two weeks ago, and I started three weeks ago. And I'm on such a low dose, just 1mg. whats your starting weight and goal weight and current weight?
 
Yeah, I do exactly that. Pitch black room and there's a noise machine. I also make sure the room is pretty cold as well. So I fall asleep pretty fast since I'm tired from my early morning workout and then the fatigue catches up to me near my bedtime. My only issue is that I keep getting up to use the bathroom lol i gotta stop drinking too much water! But I cant because reta makes me so dehydrated so im just spamming water all day.😤 . Are yall experiencing the dehydration as well?
Yes, my lips have been dry and my legs ashy lol and I've been pounding electrolyte drink like crazy and using the bathroom alot. But I think my body is getting used to the reta because I'm doing better this afternoon, experiencing no side effects now.
 
Oh wow, that's a pretty aggressive weight loss schedule. Right now, I'm at about 1.5 to 2 pounds a week.
Consistency is key. I haven't really lost anything this last week because my appetite has been getting the better of me, and I don't have access to a gym so I rely on cardio alone to push it along. I also have an extremely unfulfilling personal life and am unemployed; the earlier progress and the current plateau can both be attributed to this in a way, lol.
Sometimes it goes to 1 pound a week, but it's slowing down now because I'm getting a bit too lean.
That's a problem I wouldn't mind having.

It is pretty crazy, though, how you're experiencing appetite go up quite a bit because I haven't felt hunger since like two weeks ago, and I started three weeks ago. And I'm on such a low dose, just 1mg. whats your starting weight and goal weight and current weight?
I think appetite suppression was the best for me around the 3 week mark, at 2.3mg per week.

Starting weight was 236, current weight is around 217. 6 foot white male. Goal weight is 185, but when I get closer to 200 or the appetite suppression wears off I'm going to have to rethink my approach and gain access to a gym. I'm not a particularly motivated individual and I have poor self control, so this is all pretty difficult.

Thanks for asking me about my favorite topic 🙂
 
Yes, my lips have been dry and my legs ashy lol and I've been pounding electrolyte drink like crazy and using the bathroom alot. But I think my body is getting used to the reta because I'm doing better this afternoon, experiencing no side effects now.
Dry lips and pounding electrolyte drinks sounds like dehydration to me.

Let me red pill you on electrolytes, pretty please:

Any electrolyte drink with less than 800mg of potassium in the bottle is a scam. Coconut water is one of the best sources for potassium, and most people don't have trouble getting enough sodium.

You can take out the guesswork on potassium with a product like "Dr. Berg Electrolyte Powder" from Amazon. It has 1000mg of potassium, which is enough to be effective but not enough to be dangerous (some products have 2g of potassium). The RDA for potassium is in the neighborhood of 4g per day. I would personally add salt to a product like this. In-fact I do so every morning.

Don't sleep on salt. A bit fucking pinch of table salt in a glass of water first thing in the morning will solve 90% of your electrolyte problems and likely be more effective than expensive fruity hydration drinks. Enough that the water tastes somewhat salty and not just a little weird, but not salty like seawater. Enough that you can say, "yes, this is indeed salt water." That's your morning dose. Any product with less than 200mg of sodium isn't effectively hydrating along that route.

I usually just shake an assload of salt into a glass along with potassium salt in the morning, eyeballed in a 1:3 ratio. If I drink this, I rarely need more electrolytes later in the day unless I'm sweating a ton.

This ball knowledge has been life changing for me and I hope you take it to heart.
 
Dry lips and pounding electrolyte drinks sounds like dehydration to me.

Let me red pill you on electrolytes, pretty please:

Any electrolyte drink with less than 800mg of potassium in the bottle is a scam. Coconut water is one of the best sources for potassium, and most people don't have trouble getting enough sodium.

You can take out the guesswork on potassium with a product like "Dr. Berg Electrolyte Powder" from Amazon. It has 1000mg of potassium, which is enough to be effective but not enough to be dangerous (some products have 2g of potassium). The RDA for potassium is in the neighborhood of 4g per day. I would personally add salt to a product like this. In-fact I do so every morning.

Don't sleep on salt. A bit fucking pinch of table salt in a glass of water first thing in the morning will solve 90% of your electrolyte problems and likely be more effective than expensive fruity hydration drinks. Enough that the water tastes somewhat salty and not just a little weird, but not salty like seawater. Enough that you can say, "yes, this is indeed salt water." That's your morning dose. Any product with less than 200mg of sodium isn't effectively hydrating along that route.

I usually just shake an assload of salt into a glass along with potassium salt in the morning, eyeballed in a 1:3 ratio. If I drink this, I rarely need more electrolytes later in the day unless I'm sweating a ton.

This ball knowledge has been life changing for me and I hope you take it to heart.
Love it, thanks for the great information
 
I'm not overweight I'm actually fairly lean with a good amount of muscle. I'm 1.82m tall, weigh around 78kg, and sit at roughly 14% body fat. The problem is that it takes a lot to fight the food noise. I'm usually someone who can easily eat 5,000 calories a day without even feeling bad, so I started Retatrutide, to go for a little cut.
I started on April 23rd with 0.5mg. Three days later (April 26th), I took another 0.5mg because I felt like there was a slight peak in appetite suppression, but it faded pretty quickly.
Then on April 29th, I took 1mg straight, and last Sunday I did 1.5mg. After five days from Sunday, I'm planning to increase the dose to 2mg. Honestly, I feel pretty good on my cut right now. I still have food noise, but it's much easier to control.

The biggest difference I've noticed is digestion. When I eat a meal, it feels like it takes forever to digest, so I stay full way longer than my body is used to and my body reacts way better to carbs as pre workout, sometimes even better with an intra drink like maltodextrin, way more consistent power throughout the workout.

I'll keep track of my journey and would love to follow yours as well. I think my dose will probably end up around 3mg within the next 3–4 weeks. I'll keep you updated!
 
I was going to start low and slow with a more traditional 1 month period before titrating up. I don't have a lot of weight to lose maybe 20 to 30 pounds. I did think that once I hit that goal I would slowly titrate back down as long as I was able to maintain where I was. Seeing so many people talk about jumping up so quickly makes me wonder if my logic is flawed.
 
I was going to start low and slow with a more traditional 1 month period before titrating up. I don't have a lot of weight to lose maybe 20 to 30 pounds. I did think that once I hit that goal I would slowly titrate back down as long as I was able to maintain where I was. Seeing so many people talk about jumping up so quickly makes me wonder if my logic is flawed.
I don't think your logic is flawed. What I've been reading is people sometimes start low, eval how effective the dose is, eval side effects if any and then adjust from there?

Edit: okay that's the definition of titrate lol just looked it up
 
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Yes, my lips have been dry and my legs ashy lol and I've been pounding electrolyte drink like crazy and using the bathroom alot. But I think my body is getting used to the reta because I'm doing better this afternoon, experiencing no side effects now.
My lips are also dry as well, and I think what's going on is because of the calorie deficit daily, I get cold pretty fast and easily now. So I think it might also be happening to you as well that the cold is the reason why we are so dehydrated and lips getting dry and ashy feeling everywhere. Im constantly applying lotion now.
 
My lips are also dry as well, and I think what's going on is because of the calorie deficit daily, I get cold pretty fast and easily now. So I think it might also be happening to you as well that the cold is the reason why we are so dehydrated and lips getting dry and ashy feeling everywhere. Im constantly applying lotion now.
I've just started but my experience is that I feel warmer but not hot. I'm not sure it's dehydration at this point because my pee has been hay colored which means I'm properly hydrated. I'm also applying lotion and lip balm twice a day.
 
Consistency is key. I haven't really lost anything this last week because my appetite has been getting the better of me, and I don't have access to a gym so I rely on cardio alone to push it along. I also have an extremely unfulfilling personal life and am unemployed; the earlier progress and the current plateau can both be attributed to this in a way, lol.

That's a problem I wouldn't mind having.


I think appetite suppression was the best for me around the 3 week mark, at 2.3mg per week.

Starting weight was 236, current weight is around 217. 6 foot white male. Goal weight is 185, but when I get closer to 200 or the appetite suppression wears off I'm going to have to rethink my approach and gain access to a gym. I'm not a particularly motivated individual and I have poor self control, so this is all pretty difficult.

Thanks for asking me about my favorite topic 🙂
haha for real! its a good problem to have dw you're gonna get there eventually. as you said consistency is key.

I'm not sure what my true body fat percentage is, but the scale I use reads 11%, but I'm not sure if it's super accurate or not, but I am looking kind of like a freak, like veins everywhere and stuff.

And I think the appetite suppression was good for you at the three week mark because the half-life is six days, so as you keep pinning weekly, the reta concentration builds up in your system and so does the potency. And also, I'm not sure if this is true or not, but as you slowly lose weight, I think the reta hits you harder because there's more of it in your system and there's less of you, if that makes sense. Also, you may have to start hitting the gym and getting in the protein because you don't want the muscle to go away with the weight loss. and for motivation, you got me!! dont worry and keep the consistency going and eventually you'll hit your goal weight!! 💪💪
 
For Reta, I just went by the dosage schedule when googling Retatrutide dosing. I just switched from Reta to Tirz as the food noise was STRONG on Reta and I wasn't losing, but I actually gained 5-10lbs. I didn't taper off, I just stopped the reta and went straight to Tirz on the 4th week dose and It hasn't bothered me whatsoever and the food noise has quieted down a LOT. I will say, that .5mg increase a week isn't much of an increase. I would go by the dosage charts, but unlike Sema and Tirz, there are a few of them, just pick which one is best for you. Also, If you aren't switching, there is no need to titrate DOWN, just to get off of it, it's not going to hurt you to stop cold turkey.
 
My suggestion would be start at 1mg and see how it goes. Lots of people have enough success at 1mg and never need to go up, but I would play it by ear instead of pre-planning it out. Find the lowest effective dose that works for you and don't go up until you feel you need to.
 
I've just started but my experience is that I feel warmer but not hot. I'm not sure it's dehydration at this point because my pee has been hay colored which means I'm properly hydrated. I'm also applying lotion and lip balm twice a day.
I don't know what's going on with me then because my pee is clear, so I am drinking quite a lot of water, but my throat and tongue and all that, it gets very dry if I stop drinking water for like 10 or 20 minutes, so I'm like constantly sipping throughout the day. So maybe I am hydrated water-wise, but there must be something else. But this only started happening after I started reta.
 
My lips are also dry as well, and I think what's going on is because of the calorie deficit daily, I get cold pretty fast and easily now. So I think it might also be happening to you as well that the cold is the reason why we are so dehydrated and lips getting dry and ashy feeling everywhere. Im constantly applying lotion now.
Cold is a pretty common side (seems to come and go for me, first week was the most noticeable)
 
Pinned my second .5mg dose today. 4 days after my first dose. I was feeling great today and had no side effects this afternoon so I decided I'd give it a shot, with the weekend coming up if I have any side effects I can just ride them out if I need to. 👍🏾
 
Cold is a pretty common side (seems to come and go for me, first week was the most noticeable)
Cold is not necessarily a side effect of reta, it is a side effect of a calorie deficit. So before I started using reta, I would still get cold. And it's because I only eat one meal a day. So near the end of the day is when I eat, and that's when I am the coldest. But cold is even worse on reta for me right now because I'm in a bigger deficit.
 
I think the idea of stopping at some point is interesting. I am also already lean and am using the med to not have to struggle so much with hunger. We all kind of have an internal set point of when hunger gets turned off while eating and mine wants me to be a lot heavier than I am. I battled tooth and nail over years to get to my current weight. Now it’s easy on glp1, which I very recently started. I suspect when you stop you will drift back to your old weight but, who knows? I hope that’s not the case and you don’t need it forever.
 
I think the idea of stopping at some point is interesting. I am also already lean and am using the med to not have to struggle so much with hunger. We all kind of have an internal set point of when hunger gets turned off while eating and mine wants me to be a lot heavier than I am. I battled tooth and nail over years to get to my current weight. Now it’s easy on glp1, which I very recently started. I suspect when you stop you will drift back to your old weight but, who knows? I hope that’s not the case and you don’t need it forever.
Reta is definitely not for me or not made for someone like me, but I am using it to get absolutely shredded and maybe maintain that look year round. And I'm already extremely lean and cold basically 24/7. And when you're that lean, hunger is inevitable. But right now, on reta I feel zero hunger, zero cravings. So, I don't think I will stop, and I will probably be maintaining 1 mg a week for the rest of my life, unless I need to titrate up, which I don't think so, because I've been on 1 mg since four weeks ago. So I see really no point in stopping, because once you reach your goal weight and desired look, and you're also still pretty much keeping up that lifestyle of eating good, and working out. Then why stop? And a lot of people I've read and watched a lot of videos say once they get off of reta, the appetite is no longer being suppressed, they get hungry, and I don't want that at all. So this is more of a, like a longevity thing. And I still can eat on reta, just not as much as I used to. So I think for like maintenance and longevity purposes, you most likely will need it forever. And if you get off of it, then you will feel hungry and may drift back to your old weight.
 
I think I'll eventually be on a maintenance for the rest of my life as well for longevity and to feel great and look good. Why not? Health is the most important thing to me, especially now that I'm in my 40s. I want to be around for my family and to enjoy life as long as possible.
 
Wow, lot of interesting info here re: the side effects differences between everyone here. Helpful to know should I ever try it...

Also wasn't aware about the RHR effects. Does anyone wear a whoop or similar? Would really like to see some actual data behind it.
 
Wow, lot of interesting info here re: the side effects differences between everyone here. Helpful to know should I ever try it...

Also wasn't aware about the RHR effects. Does anyone wear a whoop or similar? Would really like to see some actual data behind it.
I'm glad I'm choosing to go low and slow. Going to bump up my 2x a week dose to .7 tomorrow.

I heard the higher resting heart rate is more an issue at higher doses 8mg/12mg?
 
I'm glad I'm choosing to go low and slow. Going to bump up my 2x a week dose to .7 tomorrow.

I heard the higher resting heart rate is more an issue at higher doses 8mg/12mg?
My HR went up 4-6 bpm from 70-72 on Reta. Currently on 8mg. I check when I got up, 68 bpm and 100% O2.
 

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