Stalled

[Iamnew2this]

Zero side effects exceot I have heartburn quite often. But I always had that, so can't blame the tirz necessarily.

I had constipation for a few months in the beginning, but that not an issue anymore.

I just had full physical and ran every test possible and they were amazed. Everything perfect

I've never heard of palpitations on tirz. I used to get them walking up stairs pre tirz. But that's cause I was carrying an extra 80 pounds up with me.

All the info that you just gave me is so valuable to me. I'm prone to getting palpatations. I got them before tirz, after, and in between. I have heart issues so, I was just curious. I'm fine taking the tirz and increasing as needed right now, but this is good to know. Ty 80 lbs is AWESOME!!!!! Congratulations to you!

 

[Galora]

All the GLP1 meds increase heart rate, it affects the vagus system if I recall correctly. For some is very subtle, for others more noticeable.

I'm part of the group that struggles with this, with +10 bpm increase of resting heart rate.
Reta would probably be a no go for me.

 

[nc.wendy]

Going from the max dose of Sema to the minimum dose of tirz could be a factor as well. It may not hurt to go ahead and bump up to 5 and see how that treats you.

This!!
After switching from S to T, it wasn't until I recently got to 10mg every 5 days before my brain/body were happy again. Keep going and be patient!

 

[Iamnew2this]

Zero side effects exceot I have heartburn quite often. But I always had that, so can't blame the tirz necessarily.

I had constipation for a few months in the beginning, but that not an issue anymore.

I just had full physical and ran every test possible and they were amazed. Everything perfect

I've never heard of palpitations on tirz. I used to get them walking up stairs pre tirz. But that's cause I was carrying an extra 80 pounds up with me.

All the info that you just gave me is so valuable to me. I'm prone to getting palpatations. I got them before tirz, after, and in between. I have heart issues so, I was just curious. I'm fine taking the tirz and increasing as needed right now, but this is good to know. Ty 80 lbs is AWESOME!!!!! Congratulations to you!

All the GLP1 meds increase heart rate, it affects the vagus system if I recall correctly. For some is very subtle, for others more noticeable.

I'm part of the group that struggles with this, with +10 bpm increase of resting heart rate.
Reta would probably be a no go for me.

I was wondering about the increase in heart rate. For me right now, my hr is ok. It's just in the future, I wouldn't mind increasing doses. I will take it a dose at a time, I guess. I feel the same way about reta. I would just love to try it, but I will have to pass.

 

[nonyabizznez]

5mg isn't a therapeutic dose.

Correcting the record here. The first level therapeutic dose of Mounjaro is 5mg. Some insurance companies will only cover one month of the .5 doses (2.5, 7.5, 12.5).

Why? Because that's how Lilly tested the drug and submitted to the FDA for approval.

 

[Iamnew2this]

Correcting the record here. The first level therapeutic dose of Mounjaro is 5mg. Some insurance companies will only cover one month of the .5 doses (2.5, 7.5, 12.5).

Why? Because that's how Lilly tested the drug and submitted to the FDA for approval.

That does sounds right. However, a lot of people don't start losing until they're up into the higher doses.

 

[Calm Logic]

And in some cases, I assume, lose some weight at 5 for a while, but it's a long four weeks until upping the dose.

Correcting the record here. The first level therapeutic dose of Mounjaro is 5mg. Some insurance companies will only cover one month of the .5 doses (2.5, 7.5, 12.5).

Why? Because that's how Lilly tested the drug and submitted to the FDA for approval.

You need to put all your knowledge in a handbook so we can quote you at the peptide parties

 

[Skidude]

And in some cases, I assume, lose some weight at 5 for a while, but it's a long four weeks until upping the dose.

You need to put all your knowledge in a handbook so we can quote you at the peptide parties

I lost 67% (41lb/18.6kg) of my total goal in the first 12 weeks on 2.5 then 5mg.
I switched to 6 as a result of food noise and lost only 1lb the following week.
Only got on scale Wed mornings and recorded, same day, same time.
I will admit to diminishing returns even with titration in the weeks that followed.

 

[Iamnew2this]

I lost 67% (41lb/18.6kg) of my total goal in the first 12 weeks on 2.5 then 5mg.
I switched to 6 as a result of food noise and lost only 1lb the following week.
Only got on scale Wed mornings and recorded, same day, same time.
I will admit to diminishing returns even with titration in the weeks that followed.
View attachment 6516

That's really great that you lost on the lower doses. Some people do respond well to the lower doses. When I was on 2.5, I lost 12 lbs. 4mg and 5mg, I did lose as well until, I wasn't losing as fast, but was losing. I increased thinking that was the thing to do. When I finally hit 7.5mg, that started off great for 5 or 6 weeks. Somewhere in the middle, my weight loss slowed down. I had to titrate up. For one month, I did not lose weight and even would go up a pound, down a pound. This went on until now, I'm at 12.5mg. So far, so good. Some people do respond well to lower doses. If you're coming off of sema at a high dose, I would think that you would have to increase your tirz dose if you're not losing any weight at that specific dose. In that case the dose that isn't working for you, is no longer therapeutic. I guess there are guidelines, and then, what would work for someone individually.

 

[Skidude]

That's really great that you lost on the lower doses. Some people do respond well to the lower doses. When I was on 2.5, I lost 12 lbs. 4mg and 5mg, I did lose as well until, I wasn't losing as fast, but was losing. I increased thinking that was the thing to do. When I finally hit 7.5mg, that started off great for 5 or 6 weeks. Somewhere in the middle, my weight loss slowed down. I had to titrate up. For one month, I did not lose weight and even would go up a pound, down a pound. This went on until now, I'm at 12.5mg. So far, so good. Some people do respond well to lower doses. If you're coming off of sema at a high dose, I would think that you would have to increase your tirz dose if you're not losing any weight at that specific dose. In that case the dose that isn't working for you, is no longer therapeutic. I guess there are guidelines, and then, what would work for someone individually.

Absolutely, it was not my intent to insinuate that everyone would have the same results, this is very unique to each person.
I also had some advantages in that I enjoy cooking, had creative meals, and watched macros. Not everyone can do that with their life/work schedules.

I do want to establish that some can, and the need to titrate up is very specific to each person and how they respond and cooperate with the peps.

If it took me 15mg I would likely do it.. by the way, I am on 12.5 now, and my reduction has slowed down significantly-

 

[Iamnew2this]

Absolutely, it was not my intent to insinuate that everyone would have the same results, this is very unique to each person.
I also had some advantages in that I enjoy cooking, had creative meals, and watched macros. Not everyone can do that with their life/work schedules.

I do want to establish that some can, and the need to titrate up is very specific to each person and how they respond and cooperate with the peps.

If it took me 15mg I would likely do it.. by the way, I am on 12.5 now, and my reduction has slowed down significantly-
View attachment 6517

Absolutely It is individual specific. Are you getting closer to your goal? I have another 30 lbs or so, and the weight is coming off slower. I've lost 73 already. I guess for me, it must be slowing down because I've lost so much already? That's also another big misconception about the higher doses, too. People automatically think that the weight should just be melting off at these doses. Maybe for some?

 

[Skidude]

Absolutely It is individual specific. Are you getting closer to your goal? I have another 30 lbs or so, and the weight is coming off slower. I've lost 73 already. I guess for me, it must be slowing down because I've lost so much already? That's also another big misconception about the higher doses, too. People automatically think that the weight should just be melting off at these doses. Maybe for some?

It is interesting it appears that regardless of how fast or slow you titrate/lose in many cases the average lost remains static.
Would I have lost more by titrating faster/slower? I am not sure.
I also added some Mots/SS31 around week 26
It is important to remember when you did your first 8-10k day on steps you were carrying much more weight. I would have to carry a 60lb bag of cement now to equal what I lost.
I am sure that effects everything.

My original goal was 185, I changed it to 163 to hit "normal" BMI
I intend to add 10lb lean at some point but am considering going down a few more lbs first to have a little room for error. currently at 24.8 BMI? (no DEXA)

 

[Iamnew2this]

It is interesting it appears that regardless of how fast or slow you titrate/lose in many cases the average lost remains static.
Would I have lost more by titrating faster/slower? I am not sure.
I also added some Mots/SS31 around week 26
It is important to remember when you did your first 8-10k day on steps you were carrying much more weight. I would have to carry a 60lb bag of cement now to equal what I lost.
I am sure that effects everything.

My original goal was 185, I changed it to 163 to hit "normal" BMI
I intend to add 10lb lean at some point but am considering going down a few more lbs first to have a little room for error. currently at 24.8 BMI? (no DEXA)

So true. You're doing fantastic! The way that you explained the 60 lb bag of cement. Smh Isn't that crazy? Crazy but true! Do you mind me asking about the Mots and ss31? Have they helped with your weight lose? I don't know too much about other peptides. My handle explains it all.

 

[Calm Logic]

The various individual experiences are always interesting to me. The average of everyone lumped up together seems very boring:

How quickly do you lose weight on Zepbound? | Zepbound weight loss

You start losing weight immediately on Zepbound. It works by helping you feel less hungry, so you eat less and lose weight. Find out more here.

www.secondnature.io

According to randomised controlled trials, you start losing weight immediately after taking Zepbound. After four weeks, the average weight loss is around 2% of body weight; after eight weeks, it’s over 4%.

Zepbound (tirzepatide) reduces appetite and hunger, helping you eat fewer calories; this effect is almost immediate.

However, you might notice the impact of lower hunger wearing off after 4-5 days post-injection in the first month of taking Zepbound.

It can take around four weeks for Zepbound to reach a level in the body we call a steady state. A steady state is when the drug’s levels in the body remain consistent rather than spiking and falling.

Interestingly, this initial weight loss is no different to other weight loss treatments or the impact of diet interventions on weight loss. The real effect of tirzepatide is seen beyond three months...

 

[Skidude]

The various individual experiences are always interesting to me. The average of everyone lumped up together seems very boring:

How quickly do you lose weight on Zepbound? | Zepbound weight loss

You start losing weight immediately on Zepbound. It works by helping you feel less hungry, so you eat less and lose weight. Find out more here.

www.secondnature.io

My stats look opposite-

 

[Iamnew2this]

The various individual experiences are always interesting to me. The average of everyone lumped up together seems very boring:

How quickly do you lose weight on Zepbound? | Zepbound weight loss

You start losing weight immediately on Zepbound. It works by helping you feel less hungry, so you eat less and lose weight. Find out more here.

www.secondnature.io

This is so interesting!

 

[Skidude]

So true. You're doing fantastic! The way that you explained the 60 lb bag of cement. Smh Isn't that crazy? Crazy but true! Do you mind me asking about the Mots and ss31? Have they helped with your weight lose? I don't know too much about other peptides. My handle explains it all.

Looking at that time period on my chart, my loss remained slow-
However, I do "feel" like it gave me energy and a "healthy" feeling.
FYI I bought another round and it is not cheap-
But as a guy in his late 50s, who may have been a bit of a partier, I felt like it would benefit me in ways I might not feel immediately.
Peps are a slippery slope, especially after the life changing results of GLP-1

 

[Iamnew2this]

Looking at that time period on my chart, my loss remained slow-
However, I do "feel" like it gave me energy and a "healthy" feeling.
FYI I bought another round and it is not cheap-
But as a guy in his late 50s, who may have been a bit of a partier, I felt like it would benefit me in ways I might not feel immediately.
Peps are a slippery slope, especially after the life changing results of GLP-1

Energy and a healthy feeling sounds good to me. Keep at it, you're doing great! This is good information for me. I remember when I turned 50. Lol These are really great things to know. Ty

 

[nonyabizznez]

That does sounds right. However, a lot of people don't start losing until they're up into the higher doses.

Both Ozempic and Mounjaro were approved for Diabetes. In the context of studies, prescriptions and insurance coverage the term "therapeutic" is not defined by what works for one individual.

Taking myself as an example I was 75 lbs overweight with glucose issues. My doctor got me approved for Mounjaro. My glucose was controlled on 2.5mg but my doctor would have to seek a new Prior Authorization every month (exception). My insurance only covers half (.5) doses for one month. We went up to 5mg where I've been for 15 months (and 78 lbs lost). The weight loss was a bonus because with my glucose under control there was no way my PCP would have increased dosage. Now I worry about my weight being too low at doctor's appointments and layer clothing accordingly!

This is just my experience but it aligns with a real doctor's prescription and a medication taken as prescribed covered by insurance. My copay with insurance avg $160/mo for one box of 5mg Mounjaro.

Why am I here? The shortages last spring were so stressful I supplemented with Lavender Sky and eventually gray. Then a letter came (last Oct enrollment time) informing me my script was under review. That's when I hoarded a lifetime supply! I've received three 84 day refills since the letter!

 

[Iamnew2this]

Both Ozempic and Mounjaro were approved for Diabetes. In the context of studies, prescriptions and insurance coverage the term "therapeutic" is not defined by what works for one individual.

Taking myself as an example I was 75 lbs overweight with glucose issues. My doctor got me approved for Mounjaro. My glucose was controlled on 2.5mg but my doctor would have to seek a new Prior Authorization every month (exception). My insurance only covers half (.5) doses for one month. We went up to 5mg where I've been for 15 months (and 78 lbs lost). The weight loss was a bonus because with my glucose under control there was no way my PCP would have increased dosage. Now I worry about my weight being too low at doctor's appointments and layer clothing accordingly!

This is just my experience but it aligns with a real doctor's prescription and a medication taken as prescribed covered by insurance. My copay with insurance avg $160/mo for one box of 5mg Mounjaro.

Why am I here? The shortages last spring were so stressful I supplemented with Lavender Sky and eventually gray. Then a letter came (last Oct enrollment time) informing me my script was under review. That's when I hoarded a lifetime supply! Yet I've received three 84 day refills since the letter!

I guess it's a lot of patience and the med being steadily in your system. I'm sure you know by now that I'm not very patientYou do have a nice stash, though. You did really great with the med. It was a win win