Stalled

Skidude said:
Absolutely, it was not my intent to insinuate that everyone would have the same results, this is very unique to each person.
I also had some advantages in that I enjoy cooking, had creative meals, and watched macros. Not everyone can do that with their life/work schedules.

I do want to establish that some can, and the need to titrate up is very specific to each person and how they respond and cooperate with the peps.

If it took me 15mg I would likely do it.. by the way, I am on 12.5 now, and my reduction has slowed down significantly-
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Absolutely 👍 It is individual specific. Are you getting closer to your goal? I have another 30 lbs or so, and the weight is coming off slower. I've lost 73 already. I guess for me, it must be slowing down because I've lost so much already? That's also another big misconception about the higher doses, too. People automatically think that the weight should just be melting off at these doses. Maybe for some?
 
Iamnew2this said:
Absolutely 👍 It is individual specific. Are you getting closer to your goal? I have another 30 lbs or so, and the weight is coming off slower. I've lost 73 already. I guess for me, it must be slowing down because I've lost so much already? That's also another big misconception about the higher doses, too. People automatically think that the weight should just be melting off at these doses. Maybe for some?
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It is interesting it appears that regardless of how fast or slow you titrate/lose in many cases the average lost remains static.
Would I have lost more by titrating faster/slower? I am not sure.
I also added some Mots/SS31 around week 26
It is important to remember when you did your first 8-10k day on steps you were carrying much more weight. I would have to carry a 60lb bag of cement now to equal what I lost.
I am sure that effects everything.

My original goal was 185, I changed it to 163 to hit "normal" BMI
I intend to add 10lb lean at some point but am considering going down a few more lbs first to have a little room for error. currently at 24.8 BMI? (no DEXA)
 
Skidude said:
It is interesting it appears that regardless of how fast or slow you titrate/lose in many cases the average lost remains static.
Would I have lost more by titrating faster/slower? I am not sure.
I also added some Mots/SS31 around week 26
It is important to remember when you did your first 8-10k day on steps you were carrying much more weight. I would have to carry a 60lb bag of cement now to equal what I lost.
I am sure that effects everything.

My original goal was 185, I changed it to 163 to hit "normal" BMI
I intend to add 10lb lean at some point but am considering going down a few more lbs first to have a little room for error. currently at 24.8 BMI? (no DEXA)
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So true. You're doing fantastic! The way that you explained the 60 lb bag of cement. Smh Isn't that crazy? Crazy but true! Do you mind me asking about the Mots and ss31? Have they helped with your weight lose? I don't know too much about other peptides. My handle explains it all.😄
 
The various individual experiences are always interesting to me. The average of everyone lumped up together seems very boring:

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How quickly do you lose weight on Zepbound? | Zepbound weight loss

You start losing weight immediately on Zepbound. It works by helping you feel less hungry, so you eat less and lose weight. Find out more here.
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According to randomised controlled trials, you start losing weight immediately after taking Zepbound. After four weeks, the average weight loss is around 2% of body weight; after eight weeks, it’s over 4%.

Zepbound (tirzepatide) reduces appetite and hunger, helping you eat fewer calories; this effect is almost immediate.

However, you might notice the impact of lower hunger wearing off after 4-5 days post-injection in the first month of taking Zepbound.

It can take around four weeks for Zepbound to reach a level in the body we call a steady state. A steady state is when the drug’s levels in the body remain consistent rather than spiking and falling.

Interestingly, this initial weight loss is no different to other weight loss treatments or the impact of diet interventions on weight loss. The real effect of tirzepatide is seen beyond three months...
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Iamnew2this said:
So true. You're doing fantastic! The way that you explained the 60 lb bag of cement. Smh Isn't that crazy? Crazy but true! Do you mind me asking about the Mots and ss31? Have they helped with your weight lose? I don't know too much about other peptides. My handle explains it all.😄
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Looking at that time period on my chart, my loss remained slow-
However, I do "feel" like it gave me energy and a "healthy" feeling.
FYI I bought another round and it is not cheap-
But as a guy in his late 50s, who may have been a bit of a partier, I felt like it would benefit me in ways I might not feel immediately.
Peps are a slippery slope, especially after the life changing results of GLP-1
 
Skidude said:
Looking at that time period on my chart, my loss remained slow-
However, I do "feel" like it gave me energy and a "healthy" feeling.
FYI I bought another round and it is not cheap-
But as a guy in his late 50s, who may have been a bit of a partier, I felt like it would benefit me in ways I might not feel immediately.
Peps are a slippery slope, especially after the life changing results of GLP-1
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Energy and a healthy feeling sounds good to me. Keep at it, you're doing great! 👍 This is good information for me. I remember when I turned 50. Lol These are really great things to know. Ty
 
Iamnew2this said:
That does sounds right. However, a lot of people don't start losing until they're up into the higher doses.
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Both Ozempic and Mounjaro were approved for Diabetes. In the context of studies, prescriptions and insurance coverage the term "therapeutic" is not defined by what works for one individual.

Taking myself as an example I was 75 lbs overweight with glucose issues. My doctor got me approved for Mounjaro. My glucose was controlled on 2.5mg but my doctor would have to seek a new Prior Authorization every month (exception). My insurance only covers half (.5) doses for one month. We went up to 5mg where I've been for 15 months (and 78 lbs lost). The weight loss was a bonus because with my glucose under control there was no way my PCP would have increased dosage. Now I worry about my weight being too low at doctor's appointments and layer clothing accordingly!

This is just my experience but it aligns with a real doctor's prescription and a medication taken as prescribed covered by insurance. My copay with insurance avg $160/mo for one box of 5mg Mounjaro.

Why am I here? The shortages last spring were so stressful I supplemented with Lavender Sky and eventually gray. Then a letter came (last Oct enrollment time) informing me my script was under review. That's when I hoarded a lifetime supply! I've received three 84 day refills since the letter! 🤷🏻‍♂️
 
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nonyabizznez said:
Both Ozempic and Mounjaro were approved for Diabetes. In the context of studies, prescriptions and insurance coverage the term "therapeutic" is not defined by what works for one individual.

Taking myself as an example I was 75 lbs overweight with glucose issues. My doctor got me approved for Mounjaro. My glucose was controlled on 2.5mg but my doctor would have to seek a new Prior Authorization every month (exception). My insurance only covers half (.5) doses for one month. We went up to 5mg where I've been for 15 months (and 78 lbs lost). The weight loss was a bonus because with my glucose under control there was no way my PCP would have increased dosage. Now I worry about my weight being too low at doctor's appointments and layer clothing accordingly!

This is just my experience but it aligns with a real doctor's prescription and a medication taken as prescribed covered by insurance. My copay with insurance avg $160/mo for one box of 5mg Mounjaro.

Why am I here? The shortages last spring were so stressful I supplemented with Lavender Sky and eventually gray. Then a letter came (last Oct enrollment time) informing me my script was under review. That's when I hoarded a lifetime supply! Yet I've received three 84 day refills since the letter! 🤷🏻‍♂️
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I guess it's a lot of patience and the med being steadily in your system. I'm sure you know by now that I'm not very patient😄You do have a nice stash, though. You did really great with the med. It was a win win 👍
 
Iamnew2this said:
I guess it's a lot of patience and the med being steadily in your system. I'm sure you know by now that I'm not very patient😄You do have a nice stash, though. You did really great with the med. It was a win win 👍
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100%!!

I paid $1057 for my first box of Mounjaro 2.5mg OOP!! So my hoard investment is a few boxes retail and I even have plan B GLPs that I haven't used (years of Sema and Cagri).

I kept paying $160/mo for $10 worth (gray) in 2024 because my doctor prescribed it and my fills are monitored (transplant patient). 2025 looks like it might be as little as $46/mo.

The piece of mind is worth way more than I've spent in my hoard. I've also been able to help a couple people gifting them what they need to lose a bit. How can I argue the benefits of GLPs then deny them a chance to try it?
 
nonyabizznez said:
100%!!

I paid $1057 for my first box of Mounjaro 2.5mg OOP!! So my hoard investment is a few boxes retail and I even have plan B GLPs that I haven't used (years of Sema and Cagri).

I kept paying $160/mo for $10 worth (gray) in 2024 because my doctor prescribed it and my fills are monitored (transplant patient). 2025 looks like it might be as little as $46/mo.

The piece of mind is worth way more than I've spent in my hoard. I've also been able to help a couple people gifting them what they need to lose a bit. How can I argue the benefits of GLPs then deny them a chance to
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nonyabizznez said:
100%!!

I paid $1057 for my first box of Mounjaro 2.5mg OOP!! So my hoard investment is a few boxes retail and I even have plan B GLPs that I haven't used (years of Sema and Cagri).

I kept paying $160/mo for $10 worth (gray) in 2024 because my doctor prescribed it and my fills are monitored (transplant patient). 2025 looks like it might be as little as $46/mo.

The piece of mind is worth way more than I've spent in my hoard. I've also been able to help a couple people gifting them what they need to lose a bit. How can I argue the benefits of GLPs then deny them a chance to try it?
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I'm just bringing this up just because. I went to my pcp 2 weeks ago and he increased my dose to 12.5mg. He sends the scripts to the pharmacy and of course, my insurance won't cover it. I asked the pharmacy how much would it cost out of pocket. They told me $1300. It's a great med, but I don't know too many people who can pay $1300 every single month. It's really sick the price they put on these meds. Especially, it helps so many.
 
Garbo said:
I hesitate to jump in here, because my views are not in keeping with the current vogue of virtuous low dosing, lol, but: To my way of thinking, you've tried every trick but the medication itself.
And the medication is why we're all here. Many of us, maybe most of us, have heroically dieted for years, with limited or short-lived success. Or great success, but damn, It was hard.

And then one day, along came sema, and then along came tirz. And omg. Everything was doable, and with so much less ... torture. The medication fixed our systems. We were happy to do the rest.

Diet tips and tricks have always been around, and they're always going to be. And they're great, and yes yes yes we should all be eating and drinking and exercising sensibly. But we are here, in the main, because we needed and were grateful to find a medication that enabled our bodies to operate correctly. Some people's bodies require very little of the meds, but for many if not most, the higher doses are where the greatest benefits are experienced.

You are on a very low dose.

I know, I know ... soooo many people say It's best to stay as low as you can. They say, After all, what will happen when you max out? Where will you go then?
And that's great advice, I guess — when the medication is working for you.

But if it's not working, what is the benefit of staying low? Indeed, what is the point of taking the medication at all?
I ask these questions sincerely, because I am often puzzled and sad that so many of our community are willing to endure a long stall, when they have at their fingertips the ability to increase their dosage until it works. 💟
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Thanks everyone for being so helpful!
 
brooke0620 said:
The last time I lost any weight was mid March 🥲
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Your body can take a break from losing weight. Typically around every 10% of body weight you lose, you will go into a stall. It can be that your body is going into survival mode to not wanting to release weight. It can be a couple weeks or longer before you start losing weight again. A lot of people don't even consider it a stall until it has been months.

You may have been too fast switching. Now you Have to ramp up the dosage into your system and you probably won't see all the effects until a higher dose since you have already been taking a GLP1. You are just going to have to be patient as you may not see the full affects of tirz if you dose per their recommendations.
 
Calm Logic said:
I remember someone saying somewhere (in other words, don't quote me), that 7.5mg of tirz is like the max dose of sema. I don't know if that's true, but it may be true for someone.

Like everyone else, I agree with upping the tirz (or whatever else you want to up). I have only been on tirz, and I went up 2.5 mg each week until I reached 10 mg.

When you were stalling with the sema, how did the food noise/cravings compare to now? In other words, are you eating more now (or wishing you were) than when you were stalling on the sema? Or are the stalls similar, including with the scale (or blood sugar or whatever)?

Something I plan to do if/when I stall for weeks is to try continuous glucose monitoring, which has always seemed interesting to me anyway (despite costing $90 a month or so). Other options include adding a non-GLP medication like phentermine or metformin. Another way to manage a stall (mostly from the world of "bro science" but it applies to women too) is to focus on gaining muscle (focusing on body composition rather than weight).
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I’ve read a LOT of great things about Metformin. Everything from improving blood sugar to making people live longer. Does it make you feel anything?
 
The only thing I felt on metformin was diarrhea 🙂 I took it a couple years ago. It may have prevented weight gain, and my A1c went down a little (like from 6.1 to 5.9).

The phentermine (which I liked more) helped with some weight loss and probably gave some energy boost. But no jitters or anything like that.
 
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