How long until Tirz kicks in?

[Man_Mar9]

Hello. I started Tirzepatide almost two weeks ago at 2.5 mg, so two shots so far. I have yet to feel the reduction in appetite and food noise.

I did get a couple of the commonly reported sides of Tirz, diarrhea and upset stomach, but very mild.

For more information, I do take three other peptides at the moment, GHRP-2 + GHRP-6, and Melanotan 2. Also I'm on TRT doses of Test(150 mg/week)

My question is do I continue Tirz at the current dose of 2.5 mg/week for the next two weeks, or do I go to 5 mg/week now and see if the appetite reduction kicks in?

 

[byefatlicia]

The suggested protocol is to do 4 weeks at 2.5mg first.
In my case, when I didn't know any better, I started my research at 5mg. I did'nt have any sides at all.
I have friends, who are a man and a woman, who started at 2.5 and bumped it to 5 after 2 weeks. Again, no sides...
The tricky thing is, you've already had sides at 2.5mg
Because of that, you might want to stay the course untill your 5th pin.

 

[Not_Your_Dad]

I'd keep with the 2.5mg and allow yourself to become accustomed. Tirz wasn't noted to consistently produce weight loss at the 2.5mg dose.

The sides do ramp up as the dose escalates (at least they did for me), so I'd be cautious and give it some time.

 

[YoYoFat]

I felt the appetite suppression and reduction of food noise within 6 hours. It took me 6 months to get up to 5mg.

 

[byefatlicia]

I felt the appetite suppression and reduction of food noise within 6 hours. It took me 6 months to get up to 5mg.

Did it take 6 months because the 2.5 was effective?

 

[Ragnar]

Hello. I started Tirzepatide almost two weeks ago at 2.5 mg, so two shots so far. I have yet to feel the reduction in appetite and food noise.

I did get a couple of the commonly reported sides of Tirz, diarrhea and upset stomach, but very mild.

For more information, I do take three other peptides at the moment, GHRP-2 + GHRP-6, and Melanotan 2. Also I'm on TRT doses of Test(150 mg/week)

My question is do I continue Tirz at the current dose of 2.5 mg/week for the next two weeks, or do I go to 5 mg/week now and see if the appetite reduction kicks in?

I went to 5mg on week 4 but I gradually worked up to this dose during the first 3 weeks. I didn’t begin to feel appetite suppression until 5mg but I was only taking the one peptide and everyone is different. If I was taking multiple peptides then I would follow the standard protocol.

 

[CallieKat]

I felt 2.5 mg on day one.

 

[nonyabizznez]

Another vote for titrating at most as directed. 4 weeks or longer each dose. I went 2.5/11wks then 5mg until goal (-75lbs). The worst thing that can happen by dosing conservatively is stretching your stash and budget.

 

[YoYoFat]

Did it take 6 months because the 2.5 was effective?

I didn't follow Eli Lilly's profit-at-scale titration schedule to go from 2.5 to 5.0. I increased by .5 at a time.

 

[byefatlicia]

I didn't follow Eli Lilly's profit-at-scale titration schedule to go from 2.5 to 5.0. I increased by .5 at a time.

That's great. But my point is: It took you that long because you responded at those doses until 6 months. That's all I was asking...