Recent content by hexagonal

  1. hexagonal

    Silly question: why do supplier discords keep getting nuked?

    Indirectly, from my understanding. My contact at discord says their primary concern is LEOs of various types - which of course are under pressure from big pharma. They're also largely concerned with the controlled substances portion, since many of these vendors are also selling HGH and anabolics.
  2. hexagonal

    KLOW research

    Angiogenesis and VEGF are well known factors for increasing tumor growth rates. There is no real debate in the science about this, to the point that anti-VEGF/angiogenesis therapies are a current hotbed of research for cancer treatment. BPC-157 and TB-500 promote angiogenesis and increased VEGF...
  3. hexagonal

    KLOW research

    I'll note that the BPC-157 and TB-500 in both GLOW and KLOW are risks for cancer. Not necessarily in causing it, but for greatly increasing cancer growth rates via angiogenesis and VEGF. TB-500 also seems likely to increase risk of metastisization of existing cancers based on the TB4 research...
  4. hexagonal

    RHR and Retatrutide

    Tirz raised my heart rate some, reta raised it a lot. I'd be surprised if tirz increased your RHR but reta did not at therapeutic doses. It impacts the sympathetic nervous system the same way tirz does, and the glucagon receptor activation is an additional mechanism for increased RHR. But 2mg...
  5. hexagonal

    How much weight have you lost?

    Down more than 80lb on the scale and up a bit more than 20lb of lean body mass per dexa in 10 months Tirz for 3 months then reta since then TRT (enough test to get me into the 700s of total T, 80mg deca for joints) for 9 months 4IU HGH for 6 months Hard lifting 5 days a week Some cardio, bad...
  6. hexagonal

    Let's talk GLP1's downfall - MUSCLE LOSS

    None of the current myostatin inhibitors work particularly well. Effect size is too small.
  7. hexagonal

    QSC - Don't call it a comeback

    Pretty much every Chinese vendor also deals in steroids. SRY, SSA, etc. As for bodybuilding, the steroid-enhanced body building world is the one that is significantly more popular. (And I would also mention that I believe that basically every single competitive sport where steroids would be...
  8. hexagonal

    Big Jump in Weight Loss After Starting Reta – Anyone Else?

    A lot of experts would disagree with you - I won't say there's universal agreement, but there's a wide variety of issues with BMI that many argue are so fundamental that it really is useless...
  9. hexagonal

    Big Jump in Weight Loss After Starting Reta – Anyone Else?

    Well, I'm here for a reason, though I've moved out of the 'obese' category, and I'm getting closer and closer to that <20% bf category, too. GLP-1s are big in the bodybuilding community for helping with cuts, though, and for bodybuilders it really is a useless metric. The verbiage of the OP...
  10. hexagonal

    Big Jump in Weight Loss After Starting Reta – Anyone Else?

    BMI is a pretty useless metric, particularly for people who engage in regular strength training. Since the OP is talking about lifting regularly, cutting phases, etc., they probably are more muscular than the average person and as such further skewed. All of this is pretty meaningless without...
  11. hexagonal

    SLU-PP-332 - This made me chuckle

    Rodent studies did 50mg per kg, which translates to about 4mg per kg for humans. Even 20mg is a massive underdose for most of us compared to the studies, though human equivalent dosing isn't always exact. If SLU does anything in humans and is safe to use in general, I suspect 20mg is far more...
  12. hexagonal

    are you concerned?

    Produced in different facilities, packaged in different ways. Not something I am concerned about, personally.
  13. hexagonal

    are you concerned?

    DNP is very yellow and is used in much higher doses. The amount of DNP needed to be of concern in a peptide vial would make it very obvious that something is wrong
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    Thoughts on tesa?

    Prescribed for visceral fat in HIV patients on specific medications - they often have significantly impacted IGF-1 levels and egrifta is used to bring it back into the normal range. https://pubmed.ncbi.nlm.nih.gov/15970280/ Personally, I think anyone with normal IGF-1 levels is increasing a...
  15. hexagonal

    Thoughts on tesa?

    Not actually trying to be funny there - just noting that the study doesn't account for what we might be doing. And who knows what all that might change! I find it plausible that under the right conditions, say, strong nutrient partitioning effects from AAS usage, increased lipolysis and...
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