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  1. TooBigtoFail

    Blood Sugar Checks?

    Never had glucose issues. I do CMP every 4-6 months. Was worried about hypoglycemia or coma, but no wild swings detected. I do titrate up very slowly.
  2. TooBigtoFail

    Storage Case

    Amazon, Essential oil carrying case, for 3ml vials. Are held firmly in. Cheap, simple, and in multiple shape and sizes.
  3. TooBigtoFail

    Airport Security Peptide

    You have the wrong state of mind. You are already making yourself guilty, and they can spot that. I recon 1 vial and put it with my checked bag, with my personal items, along my perfume bottles and other liquids (eye drops, etc). I put syringes, alcohol, etc in a separate small wrap in the...
  4. TooBigtoFail

    Pinning every 5 and 6 days.

    When you change dosage, the effect can take 1-2+weeks. Try this calculator : https://glp1plotter.com/ to help adjust dosage based on number of days. I am doing 8.5mg every 3.5 days. Read up on half-life. Worth it.
  5. TooBigtoFail

    High-Dose Tirz Weight Loss

    Congrats. Impressive. I am at 22mg peak on Tirz, so this will help me push towards a peak of 28mg. And for 8 months, wow. Are you doing occasional blood tests? Any out of range results due to higher dosage?
  6. TooBigtoFail

    My Cagri Chronicle: ongoing updates on progress with cag starting October 2024

    details? dosage, how often, for how long? any other pinning/stacking? For me, 0.8mg Cagri, once a week(5+months), with Tirz (1 year) at max dose, works very well: from zero food noise to just a bit. Not everyone react the same.
  7. TooBigtoFail

    Peptide interaction chart

    Watch out if a vial has a strong vacuum. It wants to pull in the content of the syringe. I suspect the limit is based on the amount of liquid you are willing to inject at once.
  8. TooBigtoFail

    Reta from one supplier (but not others) burning when injected.

    Try more bac. For most peps, I use 25-40u.Tirz 45u. For me, only Ghk-cu stings. Reta does not stink but am only at 1.5mg doses. When you added Bac to the 'bad' vial, was the water sucked in without pressing the syringe? That would indicate vacuum (no air) and a good sign. I always expect my...
  9. TooBigtoFail

    Tirz Freezing/Defrosting

    For Tirz, is your call: to freeze or not to freeze. Like many, I have a lot of vials of various peps and I have a good freezer where the temp is -8F (-22c), +/- 2 degrees (my Blink camera inside says so). I freeze all my lyophilized peps. According to studies and Jano, refrigeration is...
  10. TooBigtoFail

    Tirz Freezing/Defrosting

    Recommended to not refreeze due to risk of breaking the seal and allowing air/moisture in. Should be fine in frigo for 6+ months if lyophilized (Studies are all over the place on this). I would not travel by air with an ice pack of any sort or a vial with 'white powder'. I travel with...
  11. TooBigtoFail

    Bacteriostatic Solution Sodium Chloride

    Nacl is to make the solution more isotonic. From the Tirz patent: It is further desirable to match the tonicity (i.e., osmolality) of body fluids at the injection site as closely as possible when administering the compositions because solutions that are not approximately isotonic with body...
  12. TooBigtoFail

    Hospira BAC Availability

    Yes. First time. Used 25ml out of one bottle this month. Found no noticeable difference, maybe injection sites are less visible (or my skin is getting used to the pinning). Experimenting as Lilly does have Nacl in their pens (isotonic).
  13. TooBigtoFail

    Has this happened to anyone else?

    Great subject. Yes did happen. Painful learning. I recap, place in old milk jug, and then trash. I will evaluate the single hand scoop or direct trash to avoid recap. This should be on cheat sheet for newbies.
  14. TooBigtoFail

    New to Reta – Waiting on OAC, Anyone Pinned Nexaph Already?

    I have used Nexa 12mg Reta. No issues to report. Having stacked Tirz, Cagri and Reta, if food noise is annoying you, add Cagri. Low doses can reduce the food craving or completely stop you from eating altogether. Works wonder for me as I am at max dose for Tirz.
  15. TooBigtoFail

    BAC Water vs NaCl Water vs Benzyl Alcohol vs ??? :)

    I recently switched to Hospira Saline Bac with Benzyl (yes, the lime/green cap) as 'research'. I noticed that Novo and Lilly use an isotonic mixture for their glp1, which has Nacl. Why would they waste $$ adding saline? More resilient during transport? As they ship recon, maybe it helps shelf...
  16. TooBigtoFail

    Peptide interaction chart

    Anything new on this subject? Better chart? Combinations in one vial or draw from multiple vial into one syringe? I read that amino acids each have specific charges at their termini - the amino (N-terminal) and carboxyl (C-terminal) ends and mixing them will effect their 'therapeutic'...
  17. TooBigtoFail

    Which approach works for you?

    Welcome. It is good to be nervous. This is research. You will find the 'official' recommendations from Eli, Novo, Hospira, NIH and all their publications. A solid start. Then you will find folks with high risk tolerance and a passion for gambling. I keep one year supply of lyop. vials in a cube...
  18. TooBigtoFail

    Been here longer than I expected

    Welcome. Have you watched 'The Hurt Locker'? Gray has some risks. Read about it. Understand the supply chain, up to the 'pinning'. Become an RN. Am down 63# and loving the journey.
  19. TooBigtoFail

    Tuk/angel ?

    Welcome to the forum. Tuk hit a fiasco at the end of 2024. Many buyers were upset. Is now keeping a low profile on Telegram. If you search this forum, you should find the grievances. I took her off my list of suppliers. You can buy from suppliers with US warehouses. A bit more expensive but no...
  20. TooBigtoFail

    Traveling with reconstituted Tirz & Reta

    Do you fell lucky? It can be seized or you denied entry. Is not a controlled substance, and is a small amount but is well documented you need a prescription, etc. I bring a partially used Tirz recon vial with just enough left to cover for the trip. Ok for 21 days at room temperature but I place...
  21. TooBigtoFail

    Math people? Cost benefit for sema/ tirz/ reta/ cag/mix- anyone done calcs?

    Do you prefer to pay less for Sema, lose one pound a week, or paying a bit more for Tirz (or Reta) and lose 1.5 pound a week? If you reach your goal in 20-30% less time, that's money saved. Tough decision as your body may react differently. BTW, I used Reta for 10 weeks, and no measurable HR...
  22. TooBigtoFail

    Cagri finally (I think!)

    I check pH. I mix about 75% AA 0.6% and rest is bac to hit below pH5.0. Previous vial of Cagri used for 53 days. Current one 50 days old, last dose in 2 days. Does not feel degraded as I get a bit nauseous a day later, and not hungry for 2 days. May be placebo effect but is working for me.
  23. TooBigtoFail

    If you were a newb... would you start with Tirz or Reta first?

    Tirz again. Is price a concern? How much weight? Not everyone reacts the same. Don't buy 5-10mg vials. Go higher content 30 or 50mg. Buy one kit (10 vials) and stretch each vial for 6-8 weeks. Should be good for almost one year. Never tried Sema. 38 weeks on Tirz. 60# gone. 0 exercise. Stacking...
  24. TooBigtoFail

    Down the rabbit hole I go!

    Forum/ research lab / source.
  25. TooBigtoFail

    Down the rabbit hole I go!

    I started with a Compounding Pharmacy.. Yes $$$. Had to learn everything a registered nurse does as the lab supplied syringes, alcohol pads and heartburn pills. no pens. My suggestion is to get familiar with injection, sterility, reconstitution, COA, etc. You will need to acquire all the...
  26. TooBigtoFail

    Nexaph or evolve

    Same here: No more QSC, so I use Nexa, US stock. Do a pre order. 3-5 day delivery. Just did 3 orders to load up for one extra year, to avoid new trading shananigans. And I just used last dose of a 9 week old Reta recon. So much cheaper and easier to recon once, and be good for 6-8weeks.
  27. TooBigtoFail

    Reta Vendor with TFA removed.

    Don't remember ever seeing formula listed. For glp1, I always read that CN suppliers sell the salt (TFA) version. So O70 is not surprising. When I google O68, I find chem labs offering it for $700+ per vial. You could ask Janoshik what baseline they use for their lab reports and if they come...
  28. TooBigtoFail

    Anyone else experiencing Allodynia (skin sensitivity) while on Tirzepatide? Please share your experiences?

    Please explain person-specific? 3 recon'd Tirz vials, side by side tests, one from each kit. Two vials are fine, the other cause ISR. All 3 use mannitol filler, 99%+ pure. What is the variable? not me. Same skin all around. From the same vendor, one is fine and one is 'bad'. I pin every 5 days...
  29. TooBigtoFail

    Anyone else experiencing Allodynia (skin sensitivity) while on Tirzepatide? Please share your experiences?

    Been on Tirz for 9 months. I had ISR's from Glow cycle last year, while on Tirz. With more Bac water 20-30u), Glow ISR went down to almost nothing. Then I began to get ISR from my Sept 2024 Q.S.C Tirz 50mg Jano #46748 (pale orange cap). No issues when I used my Tirz 15mg batch. Tried scientific...
  30. TooBigtoFail

    Cagri nothing (!)

    Started Cagri at 0.13mg/week 11 weeks ago, increasing 0.04mg each week, now at 0.6mg/6 days. Does its job (with Tirz and Reta.). Pretty sure it takes a few weeks, not days, to build up and work.
  31. TooBigtoFail

    To filter or not to filter, that is the question

    Was not filtering. Then realized cheap Amazon bac water was risky. I began to filter using questionable EO needles, attached to questionable filter, to EO syringe made in some Asian country, to filter Bac water that could be tap water, to do recon. Was creating a much greater risk. I did buy a...
  32. TooBigtoFail

    Unable to inject meds.

    Are you explaining the problem properly? is he unable to draw from the vial, or unable to inject the dose into the skin? I would try a syringe while empty. Does the plunger glide well? how much pressure is required? There are a lot of subgrade supplies on Amazon. My Compounding pharma was...
  33. TooBigtoFail

    Hello from Florida! - Newbie first order is in hand (Nervous/Skeptical)

    Another conspiracy theory. Cinnamon, spices, imported food/candy, snacks, imported fruits, and the list goes on of heavy metal laced products. Lead paint in pre 1978 homes. Do you filter your tap water down to .5micron? Do you only buy organic? Do you smoke? Did you take a Covid vaccine? I...
  34. TooBigtoFail

    tested below 99% 😱😮😳

    If you test a one year old pep, it may test 95%, or 97% pure, not contaminated necessarily but degraded due to heat, light, etc. in its lyophilized form. There could be excipients (fillers), histidine, heavy metals, or other residuals from the fabrication. How pure is your flu shot...
  35. TooBigtoFail

    Best pep for building muscle and definition

    Go to https://thinksteroids.com/community if you really like to argue all day long about body building.
  36. TooBigtoFail

    Switching - or adding - Reta: What should I dose?

    reposting: Started Tirz 35 weeks ago. Now at 10.4mg every 5 days. Yes, slowly titrating up. To break my stall, started Cagri at 0.13mg/week, 11 weeks ago, increasing 0.04mg each week, now at 0.5mg/6 days. Cagri is a nice booster but feel a bit nauseous too easily. Never before on Tirz...
  37. TooBigtoFail

    Guidance Requested: [mod removed vendor name]=weight gain

    Depending on how long the subject stopped, to rebuild the residual level will take a few weeks, maybe 3-4, to get back to maintenance level. May not be caused by new vendor. Also, some supplier overfill by 5-10%. And some not. Jano report can help with history of fill levels. That is scary...
  38. TooBigtoFail

    Where can I find Reta trials phase 3 info

    Are you sure its not horse tranquilizer? or some other garbage? Anyway, search Retatrutide studies from Lilly, NIH, or New England Journal of Medicine. They comment/report on the dosage tried so far by Lilly, over how many weeks, body mass lost, side effects, etc. Lilly will use the results to...
  39. TooBigtoFail

    What does "sterile" mean to healthcare workers?

    Sterile: Bioburden reduction: no living bacteria, viruses, and fungi. May contain clean metal shavings, clean microscopic glass shards, rubber from vial stopper, etc. Need filtering...
  40. TooBigtoFail

    7.5 Triz to XX Reta

    Wow. I am using the slowest titration up then. Started Tirz 35 weeks ago. Now at 10.4mg every 5 days. Started Cagri at 0.13mg/week, 11 weeks ago, increasing ~0.04mg each week, now at 0.5mg/6 days. Cagri is a nice booster but feel a bit nauseous too easily. Never on Tirz. Started Reta at...
  41. TooBigtoFail

    Are peptides next?? Do you have a Plan D??

    No FDA notice for Reta or Cagri. Is still research. The glp1 demand is so high, availability will go up. There is always someone willing to take a risk to make $$$. My plan: always keep 8-12 months grey supply on hand. Jump on a good Promo. Yes, I expect to pin myself for 2-3+ years ( so I...
  42. TooBigtoFail

    My Reta came clumped up in 1 big clump

    Glad the stress level came down. The puck is 95% mannitol (sugar). Whichever way you add bac water, the puck will dissolve within a few minutes. Swirl it, roll it, it will dissolve. And, the vial is normally under vacuum, so it will pull in your bac water with no effort. If you don't have a...
  43. TooBigtoFail

    Cagrilintide sides: Anyone have advice?

    Was recently loosing only 1.3lbs per week. Started Cagri at 0.13mg/week 10 weeks ago, increased 0.04mg each week, now at 0.48mg every 6 days. Still a tad nauseous a few days after, but much less. Also going Reta 1.4mg/week, and Tirz 10.4mg every 5 days. Took 3-4weeks before Cagri/Reta made a...
  44. TooBigtoFail

    Freezers?

    I replaced the acid batteries with 2x10amp LIFEPO4 lithium in each of my 3 Cyberpower Sine Wave UPS 1500watts. I doubled the run time - 2 hours for 65" TV with DVR/settop box (120watt drain). LIFEPO4 batteries have a BMS circuit board that protects you from making mistakes. I tested the UPS...
  45. TooBigtoFail

    Sudden blurry or trippy vision degradation

    Had kidney stones after few months on Tirz. Dehydration.... Then few months later, Retinal detachment: eye pain, floaters, headache. My ophthalmologist told me to worry for two weeks after initial detachment as it could get worst. Was told is part of getting 'older'. Possible dehydration here...
  46. TooBigtoFail

    Skin feels numb

    I am not a doctor either.... Play it safe.
  47. TooBigtoFail

    Maintenance: Tirz or Reta

    Have you used both? I would pick the one that still suppress food noise. I am stacking both and plan to fade out triz, and increase reta, with the hope to maintain with Reta. I need to use up my triz before I am 100% reta. Based on research, Reta is more 3rd gen glp1. I would not be surprised...
  48. TooBigtoFail

    Amazon not shipping insulin syringes to FL anymore?

    I now use Walmart. syringe, needles, filters, etc.
  49. TooBigtoFail

    My Cagri Chronicle: ongoing updates on progress with cag starting October 2024

    I used 50% AA, 50% bac., not for fibrils but to minimize degradation. Vial is now 43 days old, no burning, no ISR. Based on that, I plan to go up near 75% AA+25% bac to get closer to pH 4.0.
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