ACE-167 + FOXO4 + Kisspeptin + Testagen

[cygnus]

Has anyone tried this stack? It seems like it'd be decent for helping to optimize natural testosterone production.

I have zero experience with any of these, but conceptually:
FOX would work on removing senescent Leydig cells
Testagen could then stimulate Leydig cells further, supporting the gene expression for protein synthesis in testes.
ACE stimulates Leydig cell function.
Kisspeptin stimulates LH and FSH, boosting testosterone.

In terms of order of operations, that seems to be right. Get rid of the bad cells, start boosting the good ones, increase them further, and then finally get the LH and FSH pushed up. I'll keep you anonymous unless you want to chime in, but thank you for the DM reminding me about Testagen and Kisspeptin.

This is more for curiosity than anything. While I'm of the age that many men have gone on TRT, I don't yet have any of the symptoms (besides being a fatty) that would warrant it and thus have avoided doing so. Not looking to toss in HCG or any of the heavier stuff for the purposes of thinking about how guys might want to approach optimizing "natural" production prior to or in lieu of exogenous hormones.

 

[Habibibi]

I've researched kisspeptin for testosterone boost. It doesn't work, unless you're ready to pin it several times a day, or do an infusion. It does acutely elevate LH and FSH reliably though.

You also need to find if you have primary or secondary hypogonadism before diving in. No amount of peptide will overcome primary hypogonadism.

I use enclomiphene now, and I've responded well to it. Good luck!