Calm Logic
GLP-1 Specialist
Gemini, with a better attitude:
Peptides with Better Freezing Stability
The stability of a reconstituted peptide in a frozen state is primarily determined by its size and amino acid sequence.
Peptides with Better Freezing Stability
The stability of a reconstituted peptide in a frozen state is primarily determined by its size and amino acid sequence.
| Peptide Type | Example (Reconned) | Why It's More Stable Frozen |
|---|---|---|
| Dipeptides/Tripeptides | Glutathione (GSH): γ-L-Glutamyl-L-cysteinylglycine (3 residues) | Simplest structure; less prone to complex aggregation upon cryoconcentration. Less susceptible to freezing damage than large proteins. |
| SS-31 (Elamipretide) | D-Arg-Dmt-Lys-Phe-NH₂ (4 residues) | Its small, linear structure makes it highly stable in frozen aliquots. |
| BPC-157 | Pentadecapeptide (15 residues) | Known to be relatively robust and is frequently stored frozen in aliquots by researchers. |