Any grey peptides for migraine headache

[mtomm]

I'm looking for this as well and not much has looked promising for migraines. It seems everyone has different experiences.

 

[birdwhacker]

Have you tried drinking a large dose of electrolytes in the morning? Research shows that the vast, vast majority of migraine headaches can be effectively treated with hydration + electrolytes.

I drink a tall glass of very salty water mixed with potassium every morning and it helps me tremendously. Just table salt + nosalt from the store in a rough 1:3 ratio, not as salty as ocean water but salty enough that it doesn't just taste weird but is noticably salty.

Obviously you want to follow up with more water later.

 

[deleted.user.16]

Have you tried drinking a large dose of electrolytes in the morning? Research shows that the vast, vast majority of migraine headaches can be effectively treated with hydration + electrolytes.

I drink a tall glass of very salty water mixed with potassium every morning and it helps me tremendously. Just table salt + nosalt from the store in a rough 1:3 ratio, not as salty as ocean water but salty enough that it doesn't just taste weird but is noticably salty.

Obviously you want to follow up with more water later.

Thanks for the tip. I've seen the research on magnesium and migraines and I already take magnesium in pill form but I can't really tell if it's done anything. Though I often forget to take it so I can't say for sure. I'll try electrolytes with potassium, just gotta remember to do it every morning lol.

Edit: whoops, sorry if you were responding to mtomm

 

[birdwhacker]

Thanks for the tip. I've seen the research on magnesium and migraines and I already take magnesium in pill form but I can't really tell if it's done anything. Though I often forget to take it so I can't say for sure. I'll try electrolytes with potassium, just gotta remember to do it every morning lol.

If you don't have potassium, just use plain salt in water. Most electrolyte drinks don't have enough to do anything besides basic rehydration in my opinion, coconut water based drinks usually have 800+mg of potassium in a serving, but the RDA is 4.5g

Like I said, I don't get migraines, but this little trick has definitely changed my life by increasing ny hydration and curing my heartburn. I started with just salt until I learned about the potassium balance.

Good luck! I have a buddy that suffered migraines, him and his sister, both of them were chronically dehydrated and refused to try this trick. He maintains that opiates were the only thing for it LOL

 

[deleted.user.16]

If you don't have potassium, just use plain salt in water. Most electrolyte drinks don't have enough to do anything besides basic rehydration in my opinion, coconut water based drinks usually have 800+mg of potassium in a serving, but the RDA is 4.5g

Like I said, I don't get migraines, but this little trick has definitely changed my life by increasing ny hydration and curing my heartburn. I started with just salt until I learned about the potassium balance.

Good luck! I have a buddy that suffered migraines, him and his sister, both of them were chronically dehydrated and refused to try this trick. He maintains that opiates were the only thing for it LOL

I already tried opiates and didn't do a damn thing besides make me dizzy and want to throw up. If black market opiates worked I'd be taking them every day.

 

[Labcat]

The ghkCu works for me to prevent migraines and make them less intense. I take it with ghk basic (basic does not do any for the migraines) and kpv (kpv does not help my migraines) to decrease the isr. I had to stop a while because the isrs were getting out of hand and I was running out of places to pin, and I miss it.

 

[RubbaDubba1]

I looked into KPV for migraines based on that infamous baseball cap dude, but from a brief scraping of the Reddits it seems more people say it causes headaches for them than cures them. Still might give it a go just because I don't have any other options.

I'm right in the middle of this, with my shoulder surgery I had 4 weeks ago and physical therapy I'm doing now FFFF! I'm having back & neck spasms, while he's trying stretch my arm out Uggh! Anyways, I'm up to 500mcg each of CJC-1295 no dac/IPamorelin everyother day, when I have PT. It's not perfect, but I feel like it keeps the headaches under control. I'm just making the case for the Secretagogues again, the Ipamorelin is most of it for me.

 

[Labcat]

I already tried opiates and didn't do a damn thing besides make me dizzy and want to throw up. If black market opiates worked I'd be taking them every day.

It’s really annoying that opiates don’t work for migraines.
I’m going to put in a plug for those new migraine meds like amovig, ajovy, and rimegepant for migraines. They are Rx and aren’t perfect with known limitations but they are life changing for many and often doctor’s offices have free samples and mfg coupons. I have seen rimegepant available on those India pharmacy lists

 

[lessthanhalf]

Just a quick plug for more standard therapies for migranes, as there are a lot and a lot of people do not know what options exist.
For acute migranes either elitriptan or ibuprofen are both extremely effective,, unfortunately does not mean they will work for everyone or every time, but success rates are very high, eletriptan has the highest initial success rate and ibuprofen has the highest success rate at no pain 24 hours later. Both are more effective than the newer Calcitonin gene-related peptide drugs though they can be useful if nsaids or tryptans are not working. Opiates can work but are avoided as much as possible due to addiction risks and they can make migranes worse or trigger them.
For frequently recurring migranes, preventive therapy is usual, and is fairly standard general practice medicine or if severe, frequent and disabling neurologists are the go. None of the peptides have any science at all of working in humans for migrane, and there are a lot of fairly effective medical treatments out there, although sometimes it can take a trial of a few different drugs to find what works best. And there are a few unlucky people who do not seem to respond well to multiple trials of medications or even botox.

 

[Labcat]

Just a quick plug for more standard therapies for migranes, as there are a lot and a lot of people do not know what options exist.
For acute migranes either elitriptan or ibuprofen are both extremely effective,, unfortunately does not mean they will work for everyone or every time, but success rates are very high, eletriptan has the highest initial success rate and ibuprofen has the highest success rate at no pain 24 hours later. Both are more effective than the newer Calcitonin gene-related peptide drugs though they can be useful if nsaids or tryptans are not working. Opiates can work but are avoided as much as possible due to addiction risks and they can make migranes worse or trigger them.
For frequently recurring migranes, preventive therapy is usual, and is fairly standard general practice medicine or if severe, frequent and disabling neurologists are the go. None of the peptides have any science at all of working in humans for migrane, and there are a lot of fairly effective medical treatments out there, although sometimes it can take a trial of a few different drugs to find what works best. And there are a few unlucky people who do not seem to respond well to multiple trials of medications or even botox.

Agree that standard therapies can be helpful, though in my experience, medical providers often rely on the basics without moving patients forward and running through the known things that help (avoiding triggers, aspirin, caffeine, nsaids. beta blockers, tryptans). But having said that, many of these standards do not help enough or have contraindications. Aspirin was fairly helpful for me but it turns out that a significant portion of people experience significant bleeding or anemia, and I was one of them. I am in the group that thinks fioricet works, though unfortunately many subscribe now to current thinking that it does not, due to one study. Botox works for some, even not injected into the trigger muscles. So can lidocaine (I see it offered everywhere for research but you all need to remember that lidocaine is a cardiac medication, and people have died in those spas)
Anyhow, my neurologist is of the opinion that the CGRPs can be safer and more effective, especially if one has other medical issues… but insurance still demands that you fail a trial of several other meds before going to the new ones (expensive because of big pharma) He reminded me that you have to fill the meds to document having trialed them but failing a trial includes rains such as not ingesting the medication.
Find a headache expert who is open minded, listens to patients, and has experience using the meds, not just beliefs about the meds. And have them help you through your personal specifics.
Migraines cause brain issues due to lack of oxygen, and current thinking also is that this causes long term permanent consequences other than days of pain, which is bad enough.

 

[lessthanhalf]

Basically agree with everything there. Doctors who actually listen are very valuable. I even had bleeding from low dose aspirin not long after starting it though I was taking it for cardiovascular reasons, thankfully it was not dramatic and just resulted in low iron numbers. I respond super well to eletriptan, though it did not help for the 20 years or more of migraines I had before it was around. And despite working nearly always, doubles the chances of another one the next day so does not always work as a solution. Not much specific research on GLP's and migraine but there is definite evidence they reduce various different chronic pain issues including neuropathic pain so they might end up finding evidence they help.

 

[Labcat]

Basically agree with everything there. Doctors who actually listen are very valuable. I even had bleeding from low dose aspirin not long after starting it though I was taking it for cardiovascular reasons, thankfully it was not dramatic and just resulted in low iron numbers. I respond super well to eletriptan, though it did not help for the 20 years or more of migraines I had before it was around. And despite working nearly always, doubles the chances of another one the next day so does not always work as a solution. Not much specific research on GLP's and migraine but there is definite evidence they reduce various different chronic pain issues including neuropathic pain so they might end up finding evidence they help.

Oh no, that is terrible about elitriptan mostly working but then doubling the chance the next day, holy 💩, that would mess with me for sure.
I wonder how many of these meds have a downside of some sort of worsening?

Glps or at least tirz apparently usually improves migraines, but shear enough perks comment they are worse that it seems clearly not for everyone. I am one of the unlucky ones, and already the professional comment I almost always get first is, but tirz usually helps migraines 🤦‍♀️. Still it helps so much with other things that I’m trying very hard to keep taking it. This why I was so pleased to find out that ghkcu works. But it has its own issues lol.

RSs with migraine, unite!

 

[Superchicken1]

Hrt drastically reduced my migraines and cluster headaches. I maybe had 5 pain free days a month. In the past 2y since starting hrt, I’ve had fewer than 10 migraines/headaches in total.

 

[deleted.user.16]

Migraines cause brain issues due to lack of oxygen, and current thinking also is that this causes long term permanent consequences other than days of pain, which is bad enough.

I read about this before and it is very scary! Apparently migraines are associated with a significantly increased risk for all-cause dementia and Alzheimer disease (though we don't know if it's a causal relationship).

But definitely a reason I want to find something that acts as a preventative rather than an abortive medication. I've tried a lot of standard meds already mentioned and the only two that work are Excedrin and triptans, which are both not great to be taking every day. I appreciate everyone's recommendations, the legit and also the sketchy ones lol.

 

[Makoto]

I looked into KPV for migraines based on that infamous baseball cap dude, but from a brief scraping of the Reddits it seems more people say it causes headaches for them than cures them. Still might give it a go just because I don't have any other options.

Maybe it's just a coincidence, but i've noticed i've had less migraines since week 2-3 of bpc+tb (and the few i've had have been less intense). Could just be a coincidence, but i'm guessing the outcome depends on what causes migraines for you (in my case it's neck/spine issues). Like other comments mention electrolytes and plenty of water does help at times, but not always, at least for me. I'm definitely considering getting KPV and Ghk-Cu when i'm done with my current "research" batch (might just get Klow tbh).