GLP-1 Forum

Anyone else having problem sleepin when on Tirz or Reta ?

Rockybalboa

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Been on Tirza for a couple of months and are switching to Reta slowly.
But ever since i started this journey my nightsleep is destroyed totally. Wake up at least 4-5 times every night and my total sleep is around 2-3 hours a night. And that is really frustrating because not even sleep medication helps.
Just want to know if anyone else has the same challenges on theese compunds and how do you manage it !
 
Are you allowing for slowed gastric emptying in the timing of taking your sleep medication? It might be hitting when you want to be awake causing the feeling of exhaustion. Just a thought.
 
Reta makes it harder for me to sleep, more than tirz did.

It’s worst the night after an injection. Splitting the weekly dose into two smaller injections helped a lot.

I’ve also been prescribed 2 mg guanfacine ER, which blunts the “wired” feeling and heart-rate rise by reducing sympathetic activity. It’s been useful for focus and blood pressure too.

For sleep, my doctor prescribed a very low dose of quetiapine (12.5–25 mg). At that level it mainly acts as an antihistamine and sedative, not as an antipsychotic. It helps with both sleep and allodynia (skin pain). Good stuff.
 
Been on Tirza for a couple of months and are switching to Reta slowly.
But ever since i started this journey my nightsleep is destroyed totally. Wake up at least 4-5 times every night and my total sleep is around 2-3 hours a night. And that is really frustrating because not even sleep medication helps.
Just want to know if anyone else has the same challenges on theese compunds and how do you manage it !
100%. My sleep was fine till I lost a certain amount of weight (wish I had written it down). Suddenly, I stared waking up anywhere between 1 hr and 2 hrs after I fell asleep. Literally, it was either 60 min, 90 min or 120 min - nothing in between. I’ve had this problem over a year.

Obviously you should double check with a doctor. But after doing a deep dive into Ben Bikman videos, I decided to try drinking exogenous ketones right before bed. I did it for the first time last night. I did not wake up once. Obviously, 1 night could be a fluke, and there have been a handful of nights where’d I’d sleep through, so I need to keep trying it. But I’ll keep you posted.
 

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