I already had problems with sleep before tirz, but it has gotten way worse since starting tirz. When I started, I took my shots at night because I read about people doing it this way so that they can sleep through the initial side effects if they were to get any. This only last about 2 shots because I couldn't fall asleep even after chamomile tea, melatonin, gaba and tryptophan. I was already taking all of this before tirz and they worked prior. I now take my shots in the morning, which has helped a bit, but I'm still not back to pre-tirz levels. I'm thinking about trying DSIP, but I need to do more research on it since reviews seem to be really mixed.