Anyone have this reaction before ?
- Thread starter JAYB820
- Start date
Gamma662keV
GLP-1 Apprentice
AMO (that's the original name of that vendor) adds something to their vials that occasionally causes this.
JAYB820
GLP-1 Apprentice
Ho
how do you deal with it? Get new vials? Add more bac water next time? I only added 100 units (1 syringe) of bac water… will adding more next time help dilute it?
I think not using 1 ml BAC for 45mg would go a long way, as stated in your other thread.
So many possibilities but amo/bff is arguably the least likely as it is widely consumed and there has not been stinging issues reported in 6+ months.
I currently pin 12.5mg of the L60 weekly.
The rest of the list of possibilities is long, but here are a few threads on it:
Search results for query: isr tirz
glp1forum.com
JAYB820
GLP-1 Apprentice
Ok
great thx. Think using 3 100 units of bac water will help?I think not using 1 ml BAC for 45mg would go a long way, as stated in your other thread.
So many possibilities but amo/bff is arguably the least likely as it is widely consumed and there has not been stinging issues reported in 6+ months.
I currently pin 12.5mg of the L60 weekly.
The rest of the list of possibilities is long, but here are a few threads on it:
Search results for query: isr tirz
tough to say, i dont know what you are pinning or what caused this.
If you are pinning 15mg you could easily put 1.5 ml/cc
but that reaction from tirz does not appear to be a concentration problem, i don't claim to be an expert but i have pinned a bunch.
That looks like either something in the water/something on the skin/cleaning was not done properly, bad BAC, or as you said in one of the many other threads you have on this- not related at all to the tirz and the prednisone will clear it up.
Did you tell telehealth you are using tirz? did they comment?
you might want to pick one thread and ask all there, you will get as better picture.
edited for typos
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JAYB820
GLP-1 Apprentice
Ok thanks! Sorry new to thread and figure it out. I have 45 mg of tirzepatide
JAYB820
GLP-1 Apprentice
I have also done sema for months through compounded pharmacies and never had an issue
JAYB820
GLP-1 Apprentice
Currently pinning 6.25 units … and thanks again. I want to figure this out and before I pin again…. May try new bac water
Personally I find that reconstituting towards achieving a fluid volume in the .2-.5ml range is usually best for most peptides.
More fluid volume also results in more accurate dosing.
More fluid volume also results in more accurate dosing.
JAYB820
GLP-1 Apprentice
Thank you and thank you for your patience as I navigate this site! I’m doing my best ! Has this reaction ever happened to you? I think it’s either bad bac water or not enough bac water for 45 mg of tirz and injecting 6.25 units just finished week 4
JAYB820
GLP-1 Apprentice
Using 100 units of water. One syringe full to mix tirz
I've never had any real ISR's (injection site reactions). About the worst I've ever had was a little PIP (post-injection pain) and on a handful of occasions a little temporary itching.
Anything other than Hospira BAC (or some of the more reliable Chinese), including the mystery bathtub waters - especially from the Amazonian Empire - is always a risk IMHO, but if you used the name-brand stuff I would easily rule that out.
The high concentration may have played a part, or it could be something as simple as your body over-reacting to the needle puncture itself or a number of other little things. Compared to others I've seen it looks pretty mild so as long as it clears up I wouldn't worry about it too much.
One of the things I learned early on in this adventure was to invest in some 3ml syringes and needles (25 gauge) to use for reconstitution. It makes the process easier and faster since a larger bore needle moves a lot more fluid a lot faster than a 30 or 31 gauge insulin syringe, and it makes using more than 1ml of fluid to reconstitute a one-step process and probably a bit more accurate.
JAYB820
GLP-1 Apprentice
Good to know thank you so much it’s been working wonders I’d hate to stop over a mild reaction. It’s usually gone in 3/4 days….
I ordered my bac water from research peptides. I’ll research and see if anyone else had reactions..
I did hear hospira brand is good. If it is the bac water I’ll order the hospira brand next before I mix my next vial .
I may try injecting just a tiny bit of bac water to see if that’s it… if not, I’ll order new needles and add more bac water to my next new vial. Thanks so much 🙂
I ordered my bac water from research peptides. I’ll research and see if anyone else had reactions..
I did hear hospira brand is good. If it is the bac water I’ll order the hospira brand next before I mix my next vial .
I may try injecting just a tiny bit of bac water to see if that’s it… if not, I’ll order new needles and add more bac water to my next new vial. Thanks so much 🙂
TooBigtoFail
GLP-1 Apprentice
For tirz, my doses are always with 45u-50u of bac, just like Eli Lilly use (yes, half of the syringe). I don't see how you can be using a precision of 6.25u? Tell me more about the syringe? a 0.3cc? I barely can see the difference between 45u and 46u on my 1cc syringe. And yes, inject 10-20u of bac by itself to see if you get isr. Can also try 90 degree pin angle in fattest belly spot. When I stack other peptides in the same syringe, I sometime end up injecting up to 75u in one place. I never use less than 25u for injecting any peps. Bac is cheap. That is just me.
JAYB820
GLP-1 Apprentice
Don't know if it is allowed to link this but I use this bacwater calculator for my tirz
primepeptides.co
How Much Bacteriostatic Water to Add to Peptides? - Prime Peptides™
This article aims to guide you through the process of determining the correct amount of bacteriostatic water to use for your peptide
primepeptides.co
FlowerFairy
GLP-1 Enthusiast
6.25 units tells us nothing. Mg. Use mg.
It's fine, but jeez they really went out of their way to make something relatively simple seem unnecessarily convoluted.Don't know if it is allowed to link this but I use this bacwater calculator for my tirz
How Much Bacteriostatic Water to Add to Peptides? - Prime Peptides™
This article aims to guide you through the process of determining the correct amount of bacteriostatic water to use for your peptide
It's also a good indicator that the owner of that shop isn't very bright. The history of the FDA going after peptide vendors is rife with examples of them targeting the low-hanging fruit of vendors openly discussing human use despite slapping the 'ol "research use only, not for human use" labels all over the place. 🤪
Normally I'm with you 100% when it comes to the whole units thing, but to be fair he did mention the specific dilution ratio in another thread.
But yeah, any time anyone refers to their dosage in units instead of mg/mL I want to reach through the screen and shake some sense into them.
JAYB820
GLP-1 Apprentice
Thsnk
Thank you so much. Sounds like to me it may be something to do with the dilution and the amount being injected. I’ll check out the link you posted for bac water and in my new vial I’ll try a new amount… ofcourse as always I’ll read and research before mixing and injecting my next vial 🙂. What is your opinion on the needles to use ?
Agree, when starting this journey I literally needed things spoon feeded. Thanks to this and other forums I have been able to learn little by little.
JAYB820
GLP-1 Apprentice
I apologize I’m new and learning how all this works. I appreciate your help and advice 🙂 it is much appreciated !
FlowerFairy
GLP-1 Enthusiast
Yeah. I saw that after I posted. And yes, it’s probably a good thing we can’t reach through the screen.
FlowerFairy
GLP-1 Enthusiast
I’m no help there- I just used the insulin needles I had left from my diabetic cat. Then switched to a pen, so I’m even less help. Theoretically the finer the gauge the less pain, but other things come into play, like drawing up the dose then injecting- that rubber stopper can dull a needle quickly.
JAYB820
GLP-1 Apprentice
The rubber stopper is tough and thick . I often wonder if a slightly longer needle will help. Whatever it is I’ll get to the bottom of it 🙂 . Thinking it’s the bac water, if not, then I’ll add more bac water in the next vial, if that’s not it I’ll try a different sized needle
