Anyone switch from Reta to Semaglutide?

[Clavicular's Hammer]

I am really enjoying Reta but sometimes find the hunger suppression is a bit wanting. I understand Semaglutide is stronger in that regard.

If anyone has made the switch what was the motivation and how would you compare the two?

Did you find Sema has a stronger appetite suppression function?

 

[Lovedog100]

That would be insane. 🤢 How much Reta are you using? If my food noise got that bad, I would either up the Reta dose, or add a small amount of Tirzepetide. Semaglutide is crap compared to Reta.

 

[J.Ayden]

Personally, I love Sema. Tbf, I've never tried anything else, but my girlfriend does Tirze. I've heard that too, that semaglutide itself is technically stronger than the other two in this one particular regard -- just food noise/appetite suppression, because it's working on a single pathway vs the rest. That's also why the dose for Sema is so much lower than the rest. Adding it would be a better shot imo than adding Tirze, as it would only be doubling up on the GLP instead of GLP and GIP, if that makes sense. I feel like you'd potentially get less side effects that way. I don't know if switching completely would make sense because you'd be missing out on the triple action that Reta has. I feel like a lot of people are hating on semaglutide these days because it's no longer the new kid on the block lol. All I can say is it's incredibly effective for me, and cheaper than the alternatives, so I'm sticking with it. I have heard that a 6mg dose of Reta is about equivalent to a 1mg dose of semaglutide, in terms of its GLP effect. I don't think it'd hurt anything to give it a try, or up your dose and see if that helps instead.

 

[chewonmysac]

That's like going from a Honda to a Hyundai.

 

[Clavicular's Hammer]

That would be insane. 🤢 How much Reta are you using? If my food noise got that bad, I would either up the Reta dose, or add a small amount of Tirzepetide. Semaglutide is crap compared to Reta.

I’m on 2mg a week split into 1mg every two days

 

[Rezwalker]

I’m on 2mg a week split into 1mg every two days

Quit the splitting ...

do a single dose and the hunger suppression will be back

 

[GLP1Pharmacist]

I’m on 2mg a week split into 1mg every two days

I'm not gonna comment on your personal care. That said Retatrutide often needs to be at least 6-8mg to really be effective for many people. I would also suggest once a week.The clinical trials use that along with higher doses.

 

[GLP1Pharmacist]

I did want to address the other comments of going down in quality , Semaglutide is a great drug and is arguably better for certain people and conditions if you follow the current evidence.

 

[Whiynot20026]

Does anyone know or have a source. Is it ok to take the Tirzep and ret the same time? I’d rather do that than split.

Bill

 

[Clavicular's Hammer]

Excuse me, 2mg split into 1mg every 4 days, not two days

Sorry for any confusion

 

[Laxfinity]

I am really enjoying Reta but sometimes find the hunger suppression is a bit wanting. I understand Semaglutide is stronger in that regard.

If anyone has made the switch what was the motivation and how would you compare the two?

Did you find Sema has a stronger appetite suppression function?

I do both.. and have for a long time. 4mg reta and 1mg sema.

That would be insane. 🤢 How much Reta are you using? If my food noise got that bad, I would either up the Reta dose, or add a small amount of Tirzepetide. Semaglutide is crap compared to Reta.

Sema is the OG.. and for some of us that have been doing this a long time (over 4 years) it is the only thing that curbs food noise.

 

[J.Ayden]

Excuse me, 2mg split into 1mg every 4 days, not two days

Sorry for any confusion

Oh yeah, especially with you being on such a low dose, I'd personally go up before I started adding or switching to anything else! I'm pretty sure the clinical trials got all the way up to 12mg. Although I'm wondering if you're having bad side effects and that's why you're on such a low, split dose? If that's the case, trying something different isn't a bad call. Or you could do your 1mg every other day, if you've found that doing more than that at once isn't sustainable for you due to side effects. If that's truly why you're on such a low dose, I worry that semaglutide could potentially cause more side effects for you, depending on what exactly is causing your side effects, which of course we have no way of knowing. But yeah, I lost >50% of my body weight (I went from 230+ to 110, weighed myself last night lol) on Sema in basically a year, mostly doing 1mg the entire time. I've been in maintenance for the last couple years but stuck with the same dose because it works for me, and going lower caused me to begin gaining weight again.

 

[mtomm]

Personally, I love Sema. Tbf, I've never tried anything else, but my girlfriend does Tirze. I've heard that too, that semaglutide itself is technically stronger than the other two in this one particular regard -- just food noise/appetite suppression, because it's working on a single pathway vs the rest. That's also why the dose for Sema is so much lower than the rest. Adding it would be a better shot imo than adding Tirze, as it would only be doubling up on the GLP instead of GLP and GIP, if that makes sense. I feel like you'd potentially get less side effects that way. I don't know if switching completely would make sense because you'd be missing out on the triple action that Reta has. I feel like a lot of people are hating on semaglutide these days because it's no longer the new kid on the block lol. All I can say is it's incredibly effective for me, and cheaper than the alternatives, so I'm sticking with it. I have heard that a 6mg dose of Reta is about equivalent to a 1mg dose of semaglutide, in terms of its GLP effect. I don't think it'd hurt anything to give it a try, or up your dose and see if that helps instead.

Same, I'm not sure why Sema has haters. It was a great drug for me.

 

[gusterbuster]

I stack sema with reta. Wanted reta for all the metabolic goodies, but suppression is meh at 8mg. Well supression was good during day and hunger would kick in late night when i was trying to sleep. Any higher, get that skin sensitivity.

Added semi and perfect. No sides, just added suppression.

Should add that adding hgh increased my hunger, like became bottomless. At 4iu hgh im on 2mg semi and 8mg reta for weightloss.