Best weight loss peps that are not GLPs?

[JokeyJo]

After two years of trying, I need to never take GLPs again. They cause terrible anhedonia for me, and Reta causes actual panic and anxiety too. I’ve experimented endlessly and it’s definitely them causing it.

I’m almost resigned to staying slightly overweight (all my diet and exercise stuff is on point) which makes me sad, but GLPs are not worth it for me.

Are there other things I can try please? Things that don’t work on reward pathways.

 

[Chili777]

Cagri works via a different channel (amylin receptors) than GLP1s and may be worth checking out. Mots-c and Tesamorelin also are said to have weight loss benefits, although Tesa works primarily on visceral fat.

 

[JokeyJo]

Cagri works via a different channel (amylin receptors) than GLP1s and may be worth checking out. Mots-c and Tesamorelin also are said to have weight loss benefits, although Tesa works primarily on visceral fat.

Thank you. Maybe a stack of those will be a good thing for me to do.

 

[Chili777]

Thank you. Maybe a stack of those will be a good thing for me to do.

NP. I'd try Cagri first and then try them one at a time. Cagri is low dose anyway. Then figure out what you can tolerate together. With Mots-c, start low there too, 1 mg and go up from there. Some people have a reaction to it.

 

[Devilseye]

I think youd be the ideal target candidate for eloralintide when it hits the grey market. It has glp1-like efficacy for weight loss while cagri seems to only be half as potent.

Cagri is still better than nothing though so id try that for now. It would be your best bet. Tesa is great for visceral fat so maybe combining cagri and tesa might work for you. Never tried it though.

 

[JokeyJo]

I think youd be the ideal target candidate for eloralintide when it hits the grey market. It has glp1-like efficacy for weight loss while cagri seems to only be half as potent.

Cagri is still better than nothing though so id try that for now. It would be your best bet. Tesa is great for visceral fat so maybe combining cagri and tesa might work for you. Never tried it though.

Thank you for the advice.

 

[emptynester]

I think youd be the ideal target candidate for eloralintide when it hits the grey market. It has glp1-like efficacy for weight loss while cagri seems to only be half as potent.

Cagri is still better than nothing though so id try that for now. It would be your best bet. Tesa is great for visceral fat so maybe combining cagri and tesa might work for you. Never tried it though.

Eloralintide causes anhedonia as well.

 

[JCO79]

I’ve experienced unanticipated effects on mood including depression and the attendant anhedonia from weight loss before ever trying GLP1 drugs. It’s a well described consequence of weight loss. Maintaining leanness below a certain point just isn’t great for mental health. Obviously that may not be the issue for you and with the effects on reward pathways it could be a direct drug effect in your case.

 

[lastresort]

Most other peptides take WEEKS to se results.

 

[Habibibi]

Cagrilintide : so effective, they had to pair it with semaglutide to be able to sell it.

 

[Smiter]

Apart from Cagri, and if you don't want dopamine-connected stuff, try bronchodilators, and anhedonia-inverters like euphoria-inducing thermogenics. Cardarine, clenbuterol, salbutamol, epicatechin, carnitine, lipo-C, tesofensene, NO boosters, fat burners with ephedra, etc.

 

[lastresort]

Epicatechin is not a peptide. Its a plant polyphenolic extract

 

[Smiter]

Epicatechin is not a peptide. Its a plant polyphenolic extract

errr...never said it was..almost all of the ones I listed are orals. Nasal inhaler version for salbutamol. Carnitine is available in both oral and injection forms.

 

[mybodyisasewer]

Apart from Cagri, and if you don't want dopamine-connected stuff, try bronchodilators, and anhedonia-inverters like euphoria-inducing thermogenics. Cardarine, clenbuterol, salbutamol, epicatechin, carnitine, lipo-C, tesofensene, NO boosters, fat burners with ephedra, etc.

Oral salbutamol is the bees knees. Effective, safe, cheap, it's a versatile drug if you're trying to cut weight, can use it to blunt hunger, or give you energy when you're tired, it is also slighty muscle sparing, so taking it fasted is more efficient for body composition. Definitely a good drug to keep around just cuz. I've never used the nasal version and honestly that sounds scary.

 

[Smiter]

I've never used the nasal version and honestly that sounds scary.

Be Afraid, be very afraid.

 

[cloratheshadow]

I agree with Cagri! Or even Tesofensine 🙂

 

[Calm Logic]

Also Clenbuterol, pretty cheap also

Cheaper than the funeral:

Tirz/Cagri vs Tirz/Reta--

I have been on Tirz for about 16 months, currently splitting a 7.5mg dose per week. I reconstituted Reta and started 1mg of that Monday, intending to repeat on Sunday. I was hoping the stack would jump start things after being in recovery from shoulder surgery, and get me back down to fighting...

glp1forum.com

Google Scholar

scholar.google.com

It's a controlled substance in New Mexico because of the risk. In some other states, it may be considered a dangerous drug, with stiffer penalties for simple possession. In the UK, up to 14 years of prison time for distribution.

The bro science is why I tried clen myself last year. Besides risking my heart health, I had the some of worst muscle pain/cramps with just "therapeutic" doses of clen, even taking a lot of taurine with it.

 

[Smiter]

Also Clenbuterol, pretty cheap also

In the early 2000's I had one of my most successful training/weight loss sessions on clen without any issues. I even competed in tournaments while under clen influence. The output difference is staggering. I know so many folks who have used clen without any issues, but I know one person who collapsed on the field after taking a 25mg dose. I used 40mg. He was 65kgs, while I was 120 then.

 

[cloratheshadow]

I removed my recommendation. I didn’t know it had such bad risks. Don’t take drugs, kids.

 

[lastresort]

I am on 250mcg CJC1295/Ipamorelin and 7.5mg reta.

I tried BAM 15 by injection just a few days ago....first day 25mg, then 5mg next day because 25mg gave me a such a bad heart palpitation. Supposdely it should not cause body thermal effect or palpitation unlike DNP, but then again there has not been any clinical study, IDK.

I had the worst fatigue yesterday, a day after pinning 5mg BAM 15. Now, I dno't know if it was BAM 15 that caused it because my mom just happend to be sick from cold but I ddn't have any cold symptoms, and my resting heartrate was 120 (!) from the morning until like 5PM.

I don't know if it was a coincidence, but this morning after a BM, I lost 2lb compared to yesterday. I know it's not water weight because I always weight myself in the morning after BM.

 

[mybodyisasewer]

I am on 250mcg CJC1295/Ipamorelin and 7.5mg reta.

I tried BAM 15 by injection just a few days ago....first day 25mg, then 5mg next day because 25mg gave me a such a bad heart palpitation. Supposdely it should not cause body thermal effect or palpitation unlike DNP, but then again there has not been any clinical study, IDK.

I had the worst fatigue yesterday, a day after pinning 5mg BAM 15. Now, I dno't know if it was BAM 15 that caused it because my mom just happend to be sick from cold but I ddn't have any cold symptoms, and my resting heartrate was 120 (!) from the morning until like 5PM.

I don't know if it was a coincidence, but this morning after a BM, I lost 2lb compared to yesterday. I know it's not water weight because I always weight myself in the morning after BM.

Damn dude that is a reckless dosing protocol. You couldn't start with 1mg and work your way up slowly to try and make sense of it? I've been thinking about bam15 and honestly your account here makes me want to try it even more because apparently it works.

 

[domin8brix]

You can try Cagri but start SUUUUPER low, like the TINIEST dose possible because that will hit you like a truck.

Unfortunately, I think you're going to encounter some form of anhedonia with any of these, since you are basically trying to numb those reward pathways by killing the majority of your appetite.

Depending on your weight/bmi/other conditions, you might also want to look into bariatric surgery, which is a more permanent option than injectibles.

 

[Smiter]

I am on 250mcg CJC1295/Ipamorelin and 7.5mg reta.

I tried BAM 15 by injection just a few days ago....first day 25mg, then 5mg next day because 25mg gave me a such a bad heart palpitation. Supposdely it should not cause body thermal effect or palpitation unlike DNP, but then again there has not been any clinical study, IDK.

I had the worst fatigue yesterday, a day after pinning 5mg BAM 15. Now, I dno't know if it was BAM 15 that caused it because my mom just happend to be sick from cold but I ddn't have any cold symptoms, and my resting heartrate was 120 (!) from the morning until like 5PM.

I don't know if it was a coincidence, but this morning after a BM, I lost 2lb compared to yesterday. I know it's not water weight because I always weight myself in the morning after BM.

I was already forced to do a PhD in fibrology. Now some1 just forced me to pursue BAM-15 as well.

 

[Smiter]

you might also want to look into bariatric surgery, which is a more permanent option than injectibles.

I second this, with one caveat. Make sure that the surgeon agrees to do a cruroplasty as well, to avoid most of the heartburn, GERD problems that might arise.

 

[domin8brix]

I second this, with one caveat. Make sure that the surgeon agrees to do a cruroplasty as well, to avoid most of the heartburn, GERD problems that might arise.

I had that done with mine, but mine was vicious before surgery. I am still on a medicine for it but it's far less strong than the one I was on for years prior to my surgery. And I have reduced it since.

 

[lastresort]

Damn dude that is a reckless dosing protocol. You couldn't start with 1mg and work your way up slowly to try and make sense of it? I've been thinking about bam15 and honestly your account here makes me want to try it even more because apparently it works.

In my defense, there is a subreddit called r/BAM15 just to discuss BAM 15, and people there ar taking anywhere between 100-200mg per day by oral. Now, I bought an oil suspension that was 50mg/mL, and I really didn't want to mess with this because I read a few horror stories about DNP, and I thought if I overdose a research compound thati s not even tested for humans yet I will endanger myself. The lowest dosage I saw was 25mg, so that's why I did that....all the "protocosl" are completely made up with no real science behind it, and there is no data on oral bioavailability so I can't convert oral dosage to injection dosage either.

I just injected 0.2mL, or 1mg, which is 1/5th of what I tried two days ago. I can immediately feel some thermic effects.

I was already forced to do a PhD in fibrology. Now some1 just forced me to pursue BAM-15 as well.

Careful there.

 

[Smiter]

I just took one puff of the salbutamol inhaler, my very first dose. I took it 30 minutes ago. About 5 minutes earlier, I started experiencing a very mild clarity, and a very slight increase in energy. Each of the puffs is supposedly at 100mcg strength. I will report on future changes if and when they happen.

 

[lastresort]

I just took one puff of the salbutamol inhaler, my very first dose. I took it 30 minutes ago. About 5 minutes earlier, I started experiencing a very mild clarity, and a very slight increase in energy. Each of the puffs is supposedly at 100mcg strength. I will report on future changes if and when they happen.

A guy I know told me it's a safer and more tolerable version of clenbuterol. I m going to try it next month.

 

[quicksilver80]

Been also trying to push the needle past this stall. Hasn't been fun. 2.5 weeks and it has been a battle. -2 +2 - 2 +2 any more ideas that arent heart intense or anxiety enducing? Had a weird experience with niacin/epicatechin/6mg rt. Think it was the niacin. Wasnt exactly my heart beating fast but it was like a feeling of dread and flushing when i stood up for a day and a half. Just under my rib cage dead center. Stopped niacin and dropped 1mg of reta and it stopped. I was eating my calorie deficit and wasnt missing anything so i know it wasnt intake or water. Been sensitive to caffiene so it might have not helped. More ideas welcomed.

 

[Galapagosfit]

I just took one puff of the salbutamol inhaler, my very first dose. I took it 30 minutes ago. About 5 minutes earlier, I started experiencing a very mild clarity, and a very slight increase in energy. Each of the puffs is supposedly at 100mcg strength. I will report on future changes if and when they happen.

my small little search on Ai tell me that the inhaler do almost nothing compare to the oral version who is more systemic and higher dosage. I want to try a blend of fat burner (Nordic flames)(50mg caffeine, 5mg albuterol(salbutamol), 5mg yohimbine) for the 2-3 last week of my cut. but i'm just beginning searching. I just want to be cautious about the anxiety sensation who comes with it. have you ever try yohimbine or the oral salbutamol?