Blood Pressure/Hypertension not dropping

[druell235]

Just curious if anyone else has had their blood pressure/hyper tension issues stay the same, despite losing lots of weight on Sema/Tirz/Reta. I have been on 20mg lisinopril and 10mg amlodipine, recently my PCP switched out the lisinopril for Lisinopril/HCTZ. Most of my other numbers look great, including my A1c which was 4.5 when we checked in August, but my last two blood pressure readings were 154/90 and 139/76 and these are pretty typical for when I go in for various doctor visits. PCP thinks its too much sodium in my food and I suspect he's right. I'm working on cutting out more sodium, but was just curious if this happened to anyone else and if you had any suggestions whether it be diet based or supplement/peptide based.

 

[Such1943]

Naturally high BP. Made this switch a few months ago with good results:

Pre-switch from Losartan: 137/87
Post-switch to Telmisartan: 116/79

Stack:
Amlodipine 10 mg
HCTZ 25 mg
Telmisartan 40 mg

Another change I was going to make was switching out HCTZ 25 mg for Chlorthalidone 12.5–25 mg, but my doc wanted to monitor the change for a few months.

 

[Foggy-Hollow]

Couple of thoughts -IANAD, just a client. I have an aortic aneurism so have entered this area earlier than some people.

With high blood pressure can come some stiffening of the blood vessels. If thats the case then I believe that part can’t be reversed. Stiffening is why BP must be treated; it spirals up on itself unfortunately.

There are a number of different meds, classified based on how they work. I think my doc said nine different classes but I can’t get google to give me a clear answer. Doc’s point was—if one doesn’t work or has sides that are negative, there’s more to try. The choice can be feathered to benefit, one example is beta blockers can ease anxiety.

Sodium is a u shaped response curve, too little is not good but too much gets all the press. When I tracked I was either eating clean (<500mg) or dirty >2500mg. My parents were low sodium when I was a teen so I just don’t salt things. 🤷‍♀️ Or I’m eating processed food with too much. Less than 500mg is also not good, electrolytes are related to the electrical impulses your body runs on. I get palpitations if I go several days like this. Track, even if just a few days to see where you are.

Third thought: Reta raises heart rate, I wouldn’t be surprise if it impacted blood pressure. If you haven’t started it yet I’d suggest to run with one of the main 2 first. Tirz has an anti-inflammatory reputation which I think would be beneficial.

It’s a game of inches since it’s the long game on this. Even if you’re over 2k on salt, if you’re under 3 take the win.

Supplement wise I’ve heard good anecdotes about beets and hibiscus tea.

Regular exercise can be regular walks. Walking is very underrated in the US.

 

[druell235]

Couple of thoughts -IANAD, just a client. I have an aortic aneurism so have entered this area earlier than some people.

With high blood pressure can come some stiffening of the blood vessels. If thats the case then I believe that part can’t be reversed. Stiffening is why BP must be treated; it spirals up on itself unfortunately.

There are a number of different meds, classified based on how they work. I think my doc said nine different classes but I can’t get google to give me a clear answer. Doc’s point was—if one doesn’t work or has sides that are negative, there’s more to try. The choice can be feathered to benefit, one example is beta blockers can ease anxiety.

Sodium is a u shaped response curve, too little is not good but too much gets all the press. When I tracked I was either eating clean (<500mg) or dirty >2500mg. My parents were low sodium when I was a teen so I just don’t salt things. 🤷‍♀️ Or I’m eating processed food with too much. Less than 500mg is also not good, electrolytes are related to the electrical impulses your body runs on. I get palpitations if I go several days like this. Track, even if just a few days to see where you are.

Third thought: Reta raises heart rate, I wouldn’t be surprise if it impacted blood pressure. If you haven’t started it yet I’d suggest to run with one of the main 2 first. Tirz has an anti-inflammatory reputation which I think would be beneficial.

It’s a game of inches since it’s the long game on this. Even if you’re over 2k on salt, if you’re under 3 take the win.

Supplement wise I’ve heard good anecdotes about beets and hibiscus tea.

Regular exercise can be regular walks. Walking is very underrated in the US.

I was stacking reta with tirz for awhile, not for the blood pressure, just to see how it went and I did not notice any difference versus high dose tirz i.e 13mg tirz vs 7.5 tirz+5reta, but I am willing to try again. I only reached the final combo for two or so weeks, will try it for longer next time.

I will confess to lots of processed/prepared foods on my end, I recently turned on the sodium tracking feature in loseit and it is not pretty.

I have been walking an hour a day since August. I started at three days a week, and now I am up to six days a week, also started some resistance/strength training in October with one of those arm trainer things.

Will definitely look into other medications. Thank you for sharing!!

 

[Foggy-Hollow]

Your welcome. Sounds like you’ve made some big changes already, Nice Work.

I’m making guesses on how the glp-1s affect BP. I haven’t reviewed the trial data with an eye toward that. If it didn’t bother then that’s good news. (Keep an eye on it of course.)

I’ve been in slight denial about my BP, I take my meds every day but don’t monitor like I should. I hate the idea of popping a med forever and it feeds into wanting to lose weight. My mom was on a laundry list of meds and I don’t want that.

There’s a few running the tirz - reta stack with good results.

 

[Slogger]

I'm interested in any way to get my BP lower. High BP is genetic on my mom's side. I've exercised my entire life, trained and ran 2 marathons, several half marathons and more, I eat a decent diet and take vitamin supplements but none of it has made any difference. High BP showed up by the time I turned 40. I'm 63 now.

I've been on tirz since July to try to lose the extra 25 pounds that showed up after menopause that I could not shed no matter what.

My brother just lost about 40 lbs this past year (with a strict diet but no peptides) in response to high BP, onset type 2 diabetes and high cholesterol. His BP has not lowered at all even though all his other numbers are great.

I would think there's got to be some kind of peptide stack or combination that can help. I'm listening...

 

[cygnus]

Beet root can reliably drop BP 10/5. I don't know if it'd be contradictive of your current meds though. Came across this on Examine years ago and was surprised how well it worked...you can get tablets cheap on Amazon.

 

[Slogger]

Beet root can reliably drop BP 10/5. I don't know if it'd be contradictive of your current meds though. Came across this on Examine years ago and was surprised how well it worked...you can get tablets cheap on Amazon.

I have tried beet root but it just didn't work for me or I didn't take it for long enough... honestly I'm ok taking something for the rest of my life but would prefer it be natural and not BP meds.