GLP-1 Forum

Can I re-inject tirz after 5 days?

FatPanda

GLP-1 Novice
Member Since
Sep 20, 2025
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Houston, TX
I took 2.5 mg of tirz on Wednesday, and it made a big difference with some mild side effects of nausea. It's been 4 days I think both benefits (as well as the side effects) are gone now. Can I give myself another 2.5 tomorrow? I know that doctors recommend not giving yourself a dose less than 5 days since your last inject with sema. I was wondering if it is safe to do so with tirz? Kind in a rapid weight gain crisis right now, so I am wondering if the benefits outweigh the risks of side effects.
 
I've been injecting Mon and Thurs for months. This works much better for me than once a week.
 
The short story is that if you're just starting with tirzepatide, stick to standard protocol of 2.5mg once a week, increasing dose by 2.5mg every four weeks. Side effects might diminish as your body gets used to it.

That said...

Tirzepatide has a half-life of five days, and some people experience food noise after that point. Most do fine on days 6 & 7.

So for that case, and when titration introduces intolerable side effects, and as a tactic to break stalls, "split-dosing" is used. There are online tools that help visualize and calculate the split... do a search.
 
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