Can't sleep

TeresaHip

TeresaHip

GLP-1 Enthusiast
Member Since
Mar 3, 2026
Posts
207
Likes Received
376
Location
La
United-States
I'm so frustrated with not being able to sleep. I go days on a couple hours of sleep a day then I crash. I'm going to have to do something. I am so tired all the time.
I might try disip.
 
TeresaHip said:
I'm so frustrated with not being able to sleep. I go days on a couple hours of sleep a day then I crash. I'm going to have to do something. I am so tired all the time.
I might try disip.
Click to expand...
DSIP has already helped some people, but I would first try to incorporate some cardio workouts into your daily routine if you aren't already doing so, or just talk to a doctor about it.
 
Bluecost10 said:
DSIP has already helped some people, but I would first try to incorporate some cardio workouts into your daily routine if you aren't already doing so, or just talk to a doctor about it.
Click to expand...
I do cardio when I can. Right now I am in a awful lupus flare.
 
I've found melatonin (the sleep hormone supplement, not a mispelled pep!) really helps. If you're not keen on that, I believe there are a range of sleep aid hot drinks available in the US without melatonin (sorry I don't know the exact brands) that you could integrate into a sleep-friendly evening routine
 
I've posted this before but it probably bears repeating. I have spent a lot of time working with people on hygiene. It really works. I am not a great sleeper myself, never will be, but I have really locked down the basics and it has helped a lot.

●Go to bed and get up at the same time. This is huge.
●No TV in the bedroom.
●Cold dark room. 68° is supposed to be ideal.
●Ideally no devices an hour before bed. I don't manage this one this, but when you put it down and get into bed DO NOT touch it until you get up for the day! Period ever.
●If you habe trouble falling asleep, look up some mindfulness techniques and practice them.
●A lot of people do better with a fan or sound machine to drown out background noises.
●No caffeine at least 6 hours before bed.
●No big meals or exercise 2 hours before bed. I have found on Tirz I need to eat a smaller dinner than I normally would and eat earlier or my sleep quality suffers.
●The bed is for sleeping (or fornicating) nothing else. If you can't sleep for more than 30 minutes, get out of bed and walk around for 5 minutes. No watching TV or anything else in bed. You want to teach your body that bed is for sleeping only.

If you are consistsnt with all of this you will likely get results. If you don't its probably time for a sleep study. I also make sure I do shots first thing in the AM so it doesn't impact my sleep.
 
5byfive said:
I've posted this before but it probably bears repeating. I have spent a lot of time working with people on hygiene. It really works. I am not a great sleeper myself, never will be, but I have really locked down the basics and it has helped a lot.

●Go to bed and get up at the same time. This is huge.
●No TV in the bedroom.
●Cold dark room. 68° is supposed to be ideal.
●Ideally no devices an hour before bed. I don't manage this one this, but when you put it down and get into bed DO NOT touch it until you get up for the day! Period ever.
●If you habe trouble falling asleep, look up some mindfulness techniques and practice them.
●A lot of people do better with a fan or sound machine to drown out background noises.
●No caffeine at least 6 hours before bed.
●No big meals or exercise 2 hours before bed. I have found on Tirz I need to eat a smaller dinner than I normally would and eat earlier or my sleep quality suffers.
●The bed is for sleeping (or fornicating) nothing else. If you can't sleep for more than 30 minutes, get out of bed and walk around for 5 minutes. No watching TV or anything else in bed. You want to teach your body that bed is for sleeping only.

If you are consistsnt with all of this you will likely get results. If you don't its probably time for a sleep study. I also make sure I do shots first thing in the AM so it doesn't impact my sleep.
Click to expand...
Yep this, I have tried everything at this point and only thing thing that ever corrects my sleep is proper maintenance. Dsip actually gave me insomnia, glycine gave me multiple awakenings, melatonin 1.5xr deffo helped some. Not massively off sleep length for defo for sleep architect. Most of the herbs you can get for sleep done nothing.
 
I've tried a bunch of things, including DSIP, Epitalon, Melatonin, Magnesium Glycinate. Nothing seems to work well for me.

I'm intrigued by this product called Anesthetized by Blackstone Labs. My hesitation is that it contains an ingredient called Phenibut, which can be habit-forming. Has anyone heard of this?
 
Generally speaking, for those of us who don't have hormonal imbalances or other underlying medical conditions, improving our sleep hygiene can make a significant difference.

I try to stop eating about three hours before bed whenever possible (around 7 p.m. for me) and I make a point of stepping away from screens by 10 p.m. These two alone have had a huge positive impact on both my sleep quality and my mental health.

I think many of us underestimate how much excessive screen time and constant exposure to news and social media can affect our well being. Often, it's not until we intentionally reduce those things that we realise just how much of a difference it makes.
 
Most underrated Peptide for sleep has to be CJC+IPA, sleep score has gone from 60-70 to 80-90 instantly since starting cycle which has been so consistent day to day. Started on 15th May to see the results!

Screenshot_20260612-132510.webp

Screenshot_20260612-132737.webp
 
Beardboost said:
Most underrated Peptide for sleep has to be CJC+IPA, sleep score has gone from 60-70 to 80-90 instantly since starting cycle which has been so consistent day to day. Started on 15th May to see the results!

View attachment 27225

View attachment 27226
Click to expand...
I bought this for that purpose, but hearing the anaphylaxis stories It still sitting in my freezer 7 months later
 
I can attest to CJC+IPA. Since starting it my sleep has significantly improved even though I am taking it first thing in the morning during a fasted state. I am also on Tirz which is why I am choosing the AM pin since Tirz can delay gastric emptying which can blunt the GH pulse.
 
NagChamp said:
I've found melatonin (the sleep hormone supplement, not a mispelled pep!) really helps. If you're not keen on that, I believe there are a range of sleep aid hot drinks available in the US without melatonin (sorry I don't know the exact brands) that you could integrate into a sleep-friendly evening routine
Click to expand...
Melatonin done nothing for me
 
FartfulCodger said:
My hesitation is that it contains an ingredient called Phenibut, which can be habit-forming. Has anyone heard of this?
Click to expand...
New to me, a brief search indicates I'd nope out on it.
Phenibut Is Neither Proven Nor Safe As A Prosocial Wonder Drug
sciencebasedmedicine.org

Phenibut Is Neither Proven Nor Safe As A Prosocial Wonder Drug

Editor's note: With Mark Crislip away on yet another vacation, we present an inaugural guest post from Abby Campbell, a practicing MD, Ph.D and contributor at HealthyButSmart.com. Welcome Abby!
sciencebasedmedicine.org

One of the biggest concerns with phenibut is that it has the potential for physical dependence, withdrawal and addiction.
 
RetCurious said:
New to me, a brief search indicates I'd nope out on it.
Phenibut Is Neither Proven Nor Safe As A Prosocial Wonder Drug
sciencebasedmedicine.org

Phenibut Is Neither Proven Nor Safe As A Prosocial Wonder Drug

Editor's note: With Mark Crislip away on yet another vacation, we present an inaugural guest post from Abby Campbell, a practicing MD, Ph.D and contributor at HealthyButSmart.com. Welcome Abby!
sciencebasedmedicine.org

One of the biggest concerns with phenibut is that it has the potential for physical dependence, withdrawal and addiction.
Click to expand...
Yeah, it's just that the reviews of it are so positive. The sensible people seem to use it just a couple times a week to get a good night's sleep. But someone else described the withdrawal symptoms as "brutal". I can't even imagine what that means. I've never been addicted to anything except maybe food.
 
NagChamp said:
I've found melatonin (the sleep hormone supplement, not a mispelled pep!) really helps.
Click to expand...
A peptide alternative is Epitalon, which raises melatonin secretion naturally:

Gemini said:
The significant drop in pineal function that severely disrupts sleep typically occurs in middle age.

Ranking Peptides for Sleep Assistance and Circadian Repair
Sermorelin ties for Rank 1 alongside DSIP, though it achieves its results through an entirely different pathway.
While DSIP directly induces the neurological state of sleep, Sermorelin acts on the endocrine system. It is a Growth Hormone-Releasing Hormone (GHRH) analogue. By age 49, the natural nocturnal pulses of growth hormone have significantly flattened out. When injected subcutaneously right before bed, Sermorelin commands the pituitary gland to release a surge of growth hormone that mimics a youthful nocturnal pulse.
Because growth hormone release is intimately tied to slow-wave (delta) sleep, this surge physically locks the brain into the deepest stages of the sleep cycle to maximize physical tissue recovery and reduce sleep fragmentation.
Here is the updated hierarchy:
| Rank | Peptide | Resulting Sleep Benefit | Best Time to Administer | PMID |
|---|---|---|---|---|
| 1 (Tie) | DSIP | Deepens delta-wave (slow-wave) sleep | 1 to 2 hours before bed | 6391925 |
| 1 (Tie) | Sermorelin | Maximizes slow-wave sleep and physical recovery | Immediately before bed (SubQ) | 8622839 |
| 2 | Epitalon | Realigns circadian rhythm over time | Evening (1–2 hours before bed) | 17969590 |
| 2 | Pinealon | Reduces nighttime awakenings over time | Morning | 21978084 |
| 3 | Selank | Calms the nervous system before sleep | 30 to 60 minutes before bed | 28280289 |
| 4 | PE-22-28 | Prevents anxiety-induced sleep disruption | Morning or afternoon | 28955242 |
Code: 
[table]
[tr]
[th]Rank[/th]
[th]Peptide[/th]
[th]Resulting Sleep Benefit[/th]
[th]Best Time to Administer[/th]
[th]PMID[/th]
[/tr]
[tr]
[td][b]1 (Tie)[/b][/td]
[td][b]DSIP[/b][/td]
[td]Deepens delta-wave (slow-wave) sleep[/td]
[td]1 to 2 hours before bed[/td]
[td]6391925[/td]
[/tr]
[tr]
[td][b]1 (Tie)[/b][/td]
[td][b]Sermorelin[/b][/td]
[td]Maximizes slow-wave sleep and physical recovery[/td]
[td]Immediately before bed (SubQ)[/td]
[td]8622839[/td]
[/tr]
[tr]
[td][b]2[/b][/td]
[td][b]Epitalon[/b][/td]
[td]Realigns circadian rhythm over time[/td]
[td]Evening (1–2 hours before bed)[/td]
[td]17969590[/td]
[/tr]
[tr]
[td][b]2[/b][/td]
[td][b]Pinealon[/b][/td]
[td]Reduces nighttime awakenings over time[/td]
[td]Morning[/td]
[td]21978084[/td]
[/tr]
[tr]
[td][b]3[/b][/td]
[td][b]Selank[/b][/td]
[td]Calms the nervous system before sleep[/td]
[td]30 to 60 minutes before bed[/td]
[td]28280289[/td]
[/tr]
[tr]
[td][b]4[/b][/td]
[td][b]PE-22-28[/b][/td]
[td]Prevents anxiety-induced sleep disruption[/td]
[td]Morning or afternoon[/td]
[td]28955242[/td]
[/tr]
[/table]
Click to expand...
 
Last edited:
Thanks everyone. I don't make decisions hastily because of my many health issues. I actually talk to my Dr at my appointment yesterday. She said there are many peptides you can try (she knows what I take) but she doesn't know much about them. I'm very sensitive to a lot of prescription meds.
 
TeresaHip said:
I'm so frustrated with not being able to sleep. I go days on a couple hours of sleep a day then I crash. I'm going to have to do something. I am so tired all the time.
I might try disip.
Click to expand...
I've only tried DSIP, and unfortunately, I didn't have any luck with it.

I switched to 2 IU of HGH before bed each night, and now I sleep like a baby.

Curious...do you use cannabis or nicotine? I found that both of those really messed up my sleep cycle.
 
modoodom said:
I've only tried DSIP, and unfortunately, I didn't have any luck with it.

I switched to 2 IU of HGH before bed each night, and now I sleep like a baby.

Curious...do you use cannabis or nicotine? I found that both of those really messed up my sleep cycle.
Click to expand...
I do but sleep has always been an issue for me. What sleep I do get is because of cannabis.
 
You must log in or register to reply here.

Trending Topics

Latest Posts

Forum Statistics

Threads
17,774
Posts
184,688
Members
59,697
Newest
AnnieOKL
Back
Top Bottom