Cycling or Life-long Use

I have no expertise in the matter at all, but one of my best personality traits is believing everything I read. This just popped up in my Reddit feed:


About to take it as gospel truth, until I read something contradictory.
Nice find and thank you for posting it.

I plan to stabilize weight loss, move into maintain mode and then reduce dose/spread dosing schedule slowly, maybe even over years. Hopefully, to get to the point it is no longer needed but will let my jean size dictate dosage. Jeans are loose, need to reduce dose or spread out dosing. Jeans are tight do the reverse. Hopefully, this works and I don't have to slowly increase dose over time to just maintain. In either case, I have plenty of stock in my freezer.
 
What dose are people on that they can lose weight and eat whatever they want? I literally have to incorporate fasting to lose weight on this. I got off my fasting and gained 10 pounds while on 7.5 mg Tz. I kinda don't like you all that just lose weight without trying.
I'm willing to bet it's people who have a LOT more weight to lose, like 80-100lbs or more--the same ones who always lose a lot in the beginning of keto diets. I have been like that so far for these first 45 lbs. Now it's slowing down and I have ~40 more to lose. The last 20-30 lbs I know won't go easily.

So most people who just have a goal of 20-30 lbs to lose probably won't have that "eat whatever and lose a lot" experience.

And if they do, they simply experience much stronger appetite suppression than others.
 
I caught a bit of the news the other day where it was reported that a new study showed that GLP-1s can have a positive effect on the gut micro biome for a long period following cessation of GLP-1s. I think a long term improvement in gut bacteria could feasibly have a continued positive effect on energy, appetite, and overall health.
Yep, and gut bacteria have an impact on your cravings. If someone changes their eating habits drastically on GLP1s, over time, their microbiome will shift, and potentially inflict different food preferences. I have been on them for 4.5 months now, and the sweet preference is still declining by the week, while my weight is stable and healthy. Before GLP1s, I could eat 90% sweets all day.
 
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