Deep Sleep Peptides

[sepehr]

Speaking of Tesamorelin, my data suggests it could affect my REM duration and overnight HRV negatively. It is something I also heard on Huberman's episode on peptides.

 

[Valerie]

DSIP, EPI, KPV, Ta-1/Thymulin.
For tough sleep issues, insomnia, circadian rhythm disruption etc, often the short, low mcg protocols won't be of much help. Longer protocols and higher dosing are usually more effective. I have all those sleep issues.

I started with DSIP, settled around 200mcg-300mcg, taken a couple of hours before I want to sleep, has helped me get much deeper sleep, but DSIP won't help get you to sleep faster. I used it nightly for 3 months, and will cycle back onto it when I need it.

A week after I began DSIP, I started EPI, and started there at 300mcg, went as high as 1mg over the course of 3 months, but 300-500mcg was the right dosing for me. With Epi, I tried it first mid-day, some it energizes, some it makes tired. It energized me, so I took it in the AM until I no longer felt it energizing me and moved it to PM, usually an hour or so after DSIP.

When I cycled off DSIP, I kept the Epi and added in KPV - lots of benefits with that pep, as with Epi, and I like that combo a lot.

When I cycled off Epi recently, I kept the KPV and when I finish my current vial, I will be trying Pinealon and either DSIP or another pep I am forgetting.

I also mixed what I call the KPV Glow - I didn't much like KPV in the ghk-cu/bpc-157/tb500(4) in part b/c the KPV and BPC-157 are in ways duplicative, but I do like the new vial I blended of ghk-cu, GHK Basic, KPV. And use that early evening. Helps as well with my sleep.

Over the course of the 3 months, I find I'm actually getting tired earlier, and my sleep anxiety has largely abated, and I'm falling instantly and deeply asleep. Even if I wake during the night, which I usually do, I'm able to fall back to sleep either instantly or within a very short time, when before I'd be up for hours.

Yesterday, to avoid getting sick I decided to start an immunity protocol of TA-1/Thymulin which runs 10-14 days, TA-1 1.5mg and THY 1mg nightly. Pinned separately. I slept very well last night using those and eager to see if it holds true tonight

The more reading I do, I am finding "longer " protocols are better. A positive impact on sleep may not be noticed for days or even weeks. Peps that help sleep don't work like sedatives so you may not notice any change in sleep the day or night you take them; admittedly this was my expectation! They build up in the system and makes changes over time.
People report taking Dsip on a Monday with improved sleep Wednesday-Friday. (I don't have the source readily available)

I've run Dsip, Pinelaon, Epithalon, ipa/cjc.
Falling asleep and staying asleep has been an issue for me for years and the older I get, the more challenging it becomes; which is unfortunate as "repair" is essential to good physical and mental health.

Initially I quit Dsip expecting quick results, but I'm back on a regular daily schedule.
It energizes me, so I take it in the morning. I have both sub q and IN. It's only been a week; nothing to report.

Epitalon; running the 10 day a month protocol. Didn't notice any effect until day 6. My body became "naturally" tired around 8:30pm - which never happens so some changes are occurring; what I can't say.

I ran Pinealon alone but not very long. It energizes me so I take it early.
It does not "induce" sleep however, I felt more refreshed when I wake. Once I finish my Dsip study, I will go back to running a full Pinealon protocol. Stimulates the pineal gland to make melatonin among other things. I'm encouraged by what I'm finding about Pinealon.

The only combo I've tried that "induces" sleep is ipa/cjc no dac. I'm doing that 5 day on 2 off protocol. It definitely works.

Edit:: final mention :: Selank is great to help induce sleep as well. I use selank and semax "as needed ".

 

[JohnnyGobbs]

Tirz and cagri 4 me lol

 

[squig33]

The more reading I do, I am finding "longer " protocols are better. A positive impact on sleep may not be noticed for days or even weeks. Peps that help sleep don't work like sedatives so you may not notice any change in sleep the day or night you take them; admittedly this was my expectation! They build up in the system and makes changes over time.
People report taking Dsip on a Monday with improved sleep Wednesday-Friday. (I don't have the source readily available)

I've run Dsip, Pinelaon, Epithalon, ipa/cjc.
Falling asleep and staying asleep has been an issue for me for years and the older I get, the more challenging it becomes; which is unfortunate as "repair" is essential to good physical and mental health.

Initially I quit Dsip expecting quick results, but I'm back on a regular daily schedule.
It energizes me, so I take it in the morning. I have both sub q and IN. It's only been a week; nothing to report.

Epitalon; running the 10 day a month protocol. Didn't notice any effect until day 6. My body became "naturally" tired around 8:30pm - which never happens so some changes are occurring; what I can't say.

I ran Pinealon alone but not very long. It energizes me so I take it early.
It does not "induce" sleep however, I felt more refreshed when I wake. Once I finish my Dsip study, I will go back to running a full Pinealon protocol. Stimulates the pineal gland to make melatonin among other things. I'm encouraged by what I'm finding about Pinealon.

The only combo I've tried that "induces" sleep is ipa/cjc no dac. I'm doing that 5 day on 2 off protocol. It definitely works.

Edit:: final mention :: Selank is great to help induce sleep as well. I use selank and semax "as needed ".

This is such a good reply! I will be looking all of those up your experiences are great to read about.

 

[Valerie]

This is such a good reply! I will be looking all of those up your experiences are great to read about.

Thank you! Feel free to dm me anytime if you have any questions

 

[Rflwr88]

Found this really helpful! I struggle with falling asleep, and then with 2 kids, deep sleep is harder to achieve.

 

[squig33]

The more reading I do, I am finding "longer " protocols are better. A positive impact on sleep may not be noticed for days or even weeks. Peps that help sleep don't work like sedatives so you may not notice any change in sleep the day or night you take them; admittedly this was my expectation! They build up in the system and makes changes over time.
People report taking Dsip on a Monday with improved sleep Wednesday-Friday. (I don't have the source readily available)

I've run Dsip, Pinelaon, Epithalon, ipa/cjc.
Falling asleep and staying asleep has been an issue for me for years and the older I get, the more challenging it becomes; which is unfortunate as "repair" is essential to good physical and mental health.

Initially I quit Dsip expecting quick results, but I'm back on a regular daily schedule.
It energizes me, so I take it in the morning. I have both sub q and IN. It's only been a week; nothing to report.

Epitalon; running the 10 day a month protocol. Didn't notice any effect until day 6. My body became "naturally" tired around 8:30pm - which never happens so some changes are occurring; what I can't say.

I ran Pinealon alone but not very long. It energizes me so I take it early.
It does not "induce" sleep however, I felt more refreshed when I wake. Once I finish my Dsip study, I will go back to running a full Pinealon protocol. Stimulates the pineal gland to make melatonin among other things. I'm encouraged by what I'm finding about Pinealon.

The only combo I've tried that "induces" sleep is ipa/cjc no dac. I'm doing that 5 day on 2 off protocol. It definitely works.

Edit:: final mention :: Selank is great to help induce sleep as well. I use selank and semax "as needed ".

Are there any biomarkers you are tracking like IGF-1 or other labs related to these as you test?

I am thinking of running a Tesa/IPA cycle. When did you dose for IPA? Before bed?

 

[cta7978]

Tried DSIP ~200mcg a couple nights alongside 1.5 IU HGH and my sleep was worse than normal.

 

[Sunflower]

For me, only Selank, passionflower and Magnolia Bark (Relora) supplements have helped induce sleep. But if taken daily, they don’t seem effective at all.

Other than Magnesium, I believe anything we take for sleep should be cycled.

 

[Valerie]

Are there any biomarkers you are tracking like IGF-1 or other labs related to these as you test?

I am thinking of running a Tesa/IPA cycle. When did you dose for IPA? Before bed?

I have not tracked bio markers or taken labs.
Ipa cjc is taken 2 hrs after eating before bed and no food 30min afterwards. Drowsy within 10 minutes, no next day hangover.

 

[Valerie]

My

Tried DSIP ~200mcg a couple nights alongside 1.5 IU HGH and my sleep was worse than normal.

Initial testing of both Dsip and Pinealon made my sleep worse as well. I moved injection time to earlier in the day as they have a stimulant effect on me; sleep has improved. It's definitely been a slow process, but there is improvement.

 

[Valerie]

Dsip protocol I'm testing.

 

[Peptoidian]

I've tried DSIP twice (as in two vials) since I specifically don't get enough deep sleep and it does very little for me. I recently started taking CJC (no DAC)+ Ipamorelin and I definitely find this helps me sleep better. I'm not sure if I'm actually getting more deep sleep, but I wake up less during the night and find myself being woken up by my alarm in the morning (vs lying awake waiting for my alarm to go off.)