Deep Sleep Peptides

[Peptoidian]

I've tried DSIP twice (as in two vials) since I specifically don't get enough deep sleep and it does very little for me. I recently started taking CJC (no DAC)+ Ipamorelin and I definitely find this helps me sleep better. I'm not sure if I'm actually getting more deep sleep, but I wake up less during the night and find myself being woken up by my alarm in the morning (vs lying awake waiting for my alarm to go off.)

 

[TRS123]

I have recently been testing DSIP and have been terribly sleepy the entire next day
Does this improve over time? Im considering abandoning the test

 

[Ted R]

I have recently been testing DSIP and have been terribly sleepy the entire next day
Does this improve over time? Im considering abandoning the test

How much has your RS been dosing?

 

[m1tkam]

I have recently been testing DSIP and have been terribly sleepy the entire next day
Does this improve over time? Im considering abandoning the test

Recently started testing DSIP + Selank intranasal and have had better deep sleep and so far woken refreshed. But you and I are not the same and like I said this is recent so I shouldn't be used as an example yet.

 

[TRS123]

RS started at 100mcg up to 150 now. sleep seems deeper but just tired all day and slight headache

 

[pavlovs]

I have used DSIP, Epitalon, and Sermorelin. None did anything for my sleep. GABA, L-theanine, L-Tryptophan and 5-HTP all work at giving me deeper sleep, according to my Oura ring. The Peps didn't change anything.

 

[Peptidenewbie]

Week 3 sermorelin. I don’t feel any changes yet.

 

[Valerie]

I've tried DSIP twice (as in two vials) since I specifically don't get enough deep sleep and it does very little for me. I recently started taking CJC (no DAC)+ Ipamorelin and I definitely find this helps me sleep better. I'm not sure if I'm actually getting more deep sleep, but I wake up less during the night and find myself being woken up by my alarm in the morning (vs lying awake waiting for my alarm to go off.)

Dsip alone I didn't have any change in sleep. I ran Epithalon for 10 days and then added Dsip. Deep sleep and total time asleep increased. Neither induced sleep; they had opposite effect for me. They both had stimulant effects ; short lived; 10-15 minutes. I moved both to earlier in the day; 4pm and 6pm.

Epithalon took at least 7 days to notice any improvement. Effect was getting sleepy on my own - which has always been a challenge. My brain takes time to shut down at night.
Dosing was 200-400mcg for both. I ran them for 30 days.
Sleep quality measured from Apple Watch and sleep app. I take 30 days off and run it again.
I've tried selank sub q early eve to help induce sleep/relaxation. I've found IN more effective for me. Sub q 150-200mcg made me very tired and extremely irritable. 😠Not fun before bed 🫤

 

[pacer22]

an Epitalon cycle worked great for me, 20 day cycle. After that CJC/no dac. And magnesium at night.

 

[beingthere]

DSIP but has to be IV administered, I did it once, it worked relatively same as first time melatonin oral, then I woke up to reality and I realised it is too much of a gamble with my health to create a habit and went back to sleeping pills. IV injecting a compound from an underground lab with 0 oversight is pushing your luck too far

 

[AndyPanda]

HGH. 2iu. An hour before bed. Unless you are under 30. Then you are probably still producing enough.

 

[Glowworm]

I have tried DSIP for about a week. It didn't help my sleep. I felt it made it a little worse. I felt I woke up more often. I didn't wear my Oura ring, so I don't have proof of sleep quality. I need to get back into the habit of wearing it. My issue is falling asleep. I can't take melatonin, because it makes me feel terrible. I have been taking Trazodone before bed for 15 years to help me fall asleep with no bad side effects. I wish I could find something that would replace Trazodone. I take magnesium before bed. I have a stash of Epitalon, but I haven't tried it yet. Maybe I will do a cycle of that before trying DSIP again.

 

[Glowworm]

DSIP but has to be IV administered, I did it once, it worked relatively same as first time melatonin oral, then I woke up to reality and I realised it is too much of a gamble with my health to create a habit and went back to sleeping pills. IV injecting a compound from an underground lab with 0 oversight is pushing your luck too far

DSIP is injected subq (belly fat) or IM (intermuscular) 2-3 hours before bedtime or mixed into a nasal spray. I have never heard of it being done as an IV. Is that done at a doctor's office?

 

[zanny-kanny]

I have tried DSIP for about a week. It didn't help my sleep. I felt it made it a little worse. I felt I woke up more often. I didn't wear my Oura ring, so I don't have proof of sleep quality. I need to get back into the habit of wearing it. My issue is falling asleep. I can't take melatonin, because it makes me feel terrible. I have been taking Trazodone before bed for 15 years to help me fall asleep with no bad side effects. I wish I could find something that would replace Trazodone. I take magnesium before bed. I have a stash of Epitalon, but I haven't tried it yet. Maybe I will do a cycle of that before trying DSIP again.

Long time insomnia sufferer here. Been taking zolpidem ER for several years now, but even with it, I sometimes cannot fall asleep at all. I also use 5HTP and magnesium glycinate.

I've recently added DSIP and Epitalon, while still taking a half a zolpidem to help with falling asleep. I tried epitalon first. Worked great the 1st day (300mcg), the 2nd day nothing. I added an extra 100mcg that same night and slept well. The next 2 days I did 400 mcg and the next day it didn't work. I added another 100mcg the next day and I slept better. The day after at 500 mcg didn't work again. I increased to 800 mcg on the following day and it was so so. I was at a loss, but thankfully the DSIP arrived. I pinned 100mcg the first night, ended up pinning another 100mcg and slept. The next night of 200 mcg was not so good - up for a couple of hours.

So I rethought my protocol and decided to cycle on and off epitalon/DSIP every other day. Epitalon still isn't working well, DSIP was doing better. Last night was epitalon time and again it didn't working so I got up around 2:00am and pinned a 100mcg of DSIP on top of the epi. Slept well the rest of the night.

It appears epitalon alone isn't the answer for me except when paired same day with DSIP. Still working on the protocol obviously. I will continue to take epitalon for the other benefits it provides and pin DSIP along with it for sleep. Crossing fingers for improved sleep.

 

[Calm Logic]

A marijuana gummy always puts me to sleep. But I don't have chronic insomia. (For use during the day, I take a quarter of a gummy.)

 

[zanny-kanny]

I wish but I would need a RX in my state. I have trouble even getting zolpidem.

 

[frankpeptid]

Long time insomnia sufferer here. Been taking zolpidem ER for several years now, but even with it, I sometimes cannot fall asleep at all. I also use 5HTP and magnesium glycinate.

I've recently added DSIP and Epitalon, while still taking a half a zolpidem to help with falling asleep. I tried epitalon first. Worked great the 1st day (300mcg), the 2nd day nothing. I added an extra 100mcg that same night and slept well. The next 2 days I did 400 mcg and the next day it didn't work. I added another 100mcg the next day and I slept better. The day after at 500 mcg didn't work again. I increased to 800 mcg on the following day and it was so so. I was at a loss, but thankfully the DSIP arrived. I pinned 100mcg the first night, ended up pinning another 100mcg and slept. The next night of 200 mcg was not so good - up for a couple of hours.

So I rethought my protocol and decided to cycle on and off epitalon/DSIP every other day. Epitalon still isn't working well, DSIP was doing better. Last night was epitalon time and again it didn't working so I got up around 2:00am and pinned a 100mcg of DSIP on top of the epi. Slept well the rest of the night.

It appears epitalon alone isn't the answer for me except when paired same day with DSIP. Still working on the protocol obviously. I will continue to take epitalon for the other benefits it provides and pin DSIP along with it for sleep. Crossing fingers for improved sleep.

If you figure it out ... let us know. I'm still trying get off ambien. 🙁

 

[zanny-kanny]

Yep, me too. I have managed to take a half a zolpidem (generic ambien) only a few of nights so far. My problem is falling asleep. Zolpidem usually works great here but there are rare times when it doesn't work at all. My goal is to be able to skip the zolpidem and go to sleep using these 2 then get back to sleep quickly whenever I get up ( at least 3 times every night). Crossing fingers.

 

[beingthere]

DSIP is injected subq (belly fat) or IM (intermuscular) 2-3 hours before bedtime or mixed into a nasal spray. I have never heard of it being done as an IV. Is that done at a doctor's office?

Delta sleep-inducing peptide alters bispectral index, the electroencephalogram and heart rate variability when used as an adjunct to isoflurane anaesthesia - PubMed

DSIP probably reduced parasympathetic tone and decreased (lightened) the depth of anaesthesia measured using BIS.

pubmed.ncbi.nlm.nih.gov

15y ago it was specifically mentioned only iv. Risks are too big to go this route so they started other ways of administering

 

[toologic]

I have had alot of luck with DSIP. It doesn't help me fall asleep but it keeps me asleep. I found that 100mcg was too much. I take 50mcg one night and 25mcg next.

 

[LuckyLukey]

The more reading I do, I am finding "longer " protocols are better. A positive impact on sleep may not be noticed for days or even weeks. Peps that help sleep don't work like sedatives so you may not notice any change in sleep the day or night you take them; admittedly this was my expectation! They build up in the system and makes changes over time.
People report taking Dsip on a Monday with improved sleep Wednesday-Friday. (I don't have the source readily available)

I've run Dsip, Pinelaon, Epithalon, ipa/cjc.
Falling asleep and staying asleep has been an issue for me for years and the older I get, the more challenging it becomes; which is unfortunate as "repair" is essential to good physical and mental health.

Initially I quit Dsip expecting quick results, but I'm back on a regular daily schedule.
It energizes me, so I take it in the morning. I have both sub q and IN. It's only been a week; nothing to report.

Epitalon; running the 10 day a month protocol. Didn't notice any effect until day 6. My body became "naturally" tired around 8:30pm - which never happens so some changes are occurring; what I can't say.

I ran Pinealon alone but not very long. It energizes me so I take it early.
It does not "induce" sleep however, I felt more refreshed when I wake. Once I finish my Dsip study, I will go back to running a full Pinealon protocol. Stimulates the pineal gland to make melatonin among other things. I'm encouraged by what I'm finding about Pinealon.

The only combo I've tried that "induces" sleep is ipa/cjc no dac. I'm doing that 5 day on 2 off protocol. It definitely works.

Edit:: final mention :: Selank is great to help induce sleep as well. I use selank and semax "as needed ".

Do you use Selank in the PM? I use Selank in the AM 3x/week right now and have noticed that it makes me generally more productive. Yesterday was my 10th day of DSIP & EPI one hour before bed and I'm struggling with getting to sleep and staying asleep-prior to starting them I was only having the wakig at 2:30am problem. I'm gonna have to research timing of those peps more as your timing is different than standard protocols and now I'm wondering if I shouldn't adjust the timing to the afternoon. I know there are some people who are enegized with magnesium glycinate and they have to take it earlier in the day becasue it impacts their ability to sleep so I'm thinking this is something similar. Glad I came across your post.