Does stacking Ipamorelin with Tesamorelin make that big of a difference?

[IronCircuit]

I see some conflicting information and wondering if I can get any anecdotal evidence in regard.

I’m looking at a Tesa/Ipa blend and have read positive reviews, but wondering if the Ipa adds that much more to what Tesa is doing to make it worth the increased cost.

 

[Calm Logic]

Regarding results of taking both, a well-elevated rise in this example (baseline was "in range"), so probably better than taking just tesa:

Will have to wait for the DEXA in a few weeks to see what, if any, impact it had on visceral fat and muscle growth, but:

.300mgish of ipa, 2mg of tesa nightly after 2+ hours of fasting, 5 days on, 2 days off.

Glucose increased from 92 to 105 (Slightly out of range)
Insulin increased from to 46.2 from 22.4 (Moderately out of range)
HbA1c dropped from 5.2 to 5 (Optimal range)
IGF-1 increased to 351 (Teen/Early 20s range)


Insulin levels are probably the most interesting here - most indications are that when IGF-1/GH levels drop, insulin resistance drops pretty quickly as well, which underscores why a lot of recommendations around this are to cycle off rather than being on it indefinitely. I've got one week left for this kit, so I'll do the full 10 weeks and then take some time off and see how all of those levels fare. In theory that insulin level would be beneficial for muscle growth, but not something I would want to risk long term.

I've got some HGH so I might see how I respond to it at 2IU and 4IU a day, with the same 5 days on 2 days off I did with ipa/tesa.

But if buying a blend (already mixed), the biggest issue to me would be potential immune reactions (from any significant cross-aggregation after recon).