Enclomiphene Results (Month 1)

mraajr

mraajr

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A month-ish ago I started taking Enclomiphene (12.5 mg ED). Total testosterone is up from 458 to 1100. Estradiol up from 18 to 41. Free testosterone is up from 63 to 190. The estradiol number is the one I am slightly concerned with, but given the ratio of total test/estradiol, I do not believe it to be too high. Though I have definitely noticed a slight increase in emotional response. Not anger or anything like that. Just that sappy videos and stories seem to make me a bit more emotional than I feel like they probably have in the past, if that makes sense.

It seems like no matter what peptide/drug, etc., I take, I respond extremely well to it. Does anyone think I should possibly cut the dose in half, or are these numbers relatively good? Just looking for some experiences other people have had on Enclo.
 
mraajr said:
A month-ish ago I started taking Enclomiphene (12.5 mg ED). Total testosterone is up from 458 to 1100. Estradiol up from 18 to 41. Free testosterone is up from 63 to 190. The estradiol number is the one I am slightly concerned with, but given the ratio of total test/estradiol, I do not believe it to be too high. Though I have definitely noticed a slight increase in emotional response. Not anger or anything like that. Just that sappy videos and stories seem to make me a bit more emotional than I feel like they probably have in the past, if that makes sense.

It seems like no matter what peptide/drug, etc., I take, I respond extremely well to it. Does anyone think I should possibly cut the dose in half, or are these numbers relatively good? Just looking for some experiences other people have had on Enclo.
Click to expand...
FWIW, I tried 12.5 mg/caps clomiphene first. Starting testo was 403. Went to 749 after one month and Estradiol also went up from 25.4 to 47.6.
Switched to Enclomiphene, 12.5 mg oral. One month later, testo was 896 and Estradiol went back down to 36.1. Free T went from 5.5 to 9.4 over that 60 days.
 
So let me ask this. I'm seeing multiple doses from various sellers. 50mg, 25mg and 12.5mg. Is 12.5mg just the cheapest or are prices similar across the doses? I know Clomid comes in 50mg pills but is the price difference that much more? I've been really looking into it, but don't know if I should. I gained weight on Clomid and had to stop because of it.
 
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mraajr said:
A month-ish ago I started taking Enclomiphene (12.5 mg ED). Total testosterone is up from 458 to 1100. Estradiol up from 18 to 41. Free testosterone is up from 63 to 190. The estradiol number is the one I am slightly concerned with, but given the ratio of total test/estradiol, I do not believe it to be too high. Though I have definitely noticed a slight increase in emotional response. Not anger or anything like that. Just that sappy videos and stories seem to make me a bit more emotional than I feel like they probably have in the past, if that makes sense.

It seems like no matter what peptide/drug, etc., I take, I respond extremely well to it. Does anyone think I should possibly cut the dose in half, or are these numbers relatively good? Just looking for some experiences other people have had on Enclo.
Click to expand...
Ah the clomid therapy they've been using many years in Europe. In the US they can't wait to feed you testosterone and get that prostate swole. Impressive results, I had no idea it could double or triple you're numbers.... I don't think the estrogen is high and if you feel well and aren't retaining water and have no sides then that works. I think we consider desirable estrogen between 10-40 but they say even 50 is ok.... when I blast aas I come in at 95 and take an aromatose inhibitor.
 
Airborne Daddy said:
Ah the clomid therapy they've been using many years in Europe. In the US they can't wait to feed you testosterone and get that prostate swole. Impressive results, I had no idea it could double or triple you're numbers.... I don't think the estrogen is high and if you feel well and aren't retaining water and have no sides then that works. I think we consider desirable estrogen between 10-40 but they say even 50 is ok.... when I blast aas I come in at 95 and take an aromatose inhibitor.
Click to expand...

I was floored when I read the results. I could not believe it got my test that high in such a short amount of time. I didn't want to go straight to test, so I figured Enclo would be worth trying. I am probably retaining some water, but part of that is from MK677 and Tesamorelin also. My estrogen went up almost the exact same percentage as my testosterone, so I figured 41 wasn't too bad, although it was on the higher end of the reference range.
 
IshimaruKenta said:
So let me ask this. I'm seeing multiple doses from various sellers. 50mg, 25mg and 12.5mg. Is 12.5mg just the cheapest or are prices similar across the doses? I know Clomid comes in 50mg pills but is the peice difference that much more? I've been really looking into it, but don't know if I should. I gained weight on Clomid and had to stop because of it.
Click to expand...

From what I have seen, the higher you go in mg, the better deal you get. I just went with the 12.5 mg capsules because that was the dosage that I wanted to take. I think I could probably cut it back to 6.25 and be fine, albeit maybe with a slightly lower test number.

I did not want to try Clomid because of the propensity to raise your estradiol levels beyond a desirable amount. That is supposed to have been mitigated almost completely with the Enclo.
 
Does enclomiphene cause you to gain weight/retain water?
 
IshimaruKenta said:
Does enclomiphene cause you to gain weight/retain water?
Click to expand...

It is hard to speak on the water retention because I also take MK-677 and Tesamorelin, both of which can cause you to retain water. I do think I hold a bit of extra water weight, but I am unsure which of the three is causing it.

I have not gained any weight on it, but I am also in a pretty significant calorie deficit on Reta.
 
IshimaruKenta said:
Does enclomiphene cause you to gain weight/retain water?
Click to expand...
I do not find myself retaining water at all and I have been using enclomipohene and Tesamorelin since the beginning of August. I read about a lot of others retaining water but that has definitely not been the case for me. No bloat whatsoever. And I've lost a steady 1-1/2 to 2 lbs every week since then also.
 
How do you know its enclo and bot chlomid what alot of suppliers do?
 
Just had to stop. Started about the same time as Reta. Was dosing 12.5mg eod for first 6 weeks. Then bumped to every day. Last week started having some minor vision issues, which being old(44) I kind of dismissed until I saw a post mentioning this as a side effect to enclomiphene.

Just bringing this up as something to watch out for.
 
yrrdead said:
Just had to stop. Started about the same time as Reta. Was dosing 12.5mg eod for first 6 weeks. Then bumped to every day. Last week started having some minor vision issues, which being old(44) I kind of dismissed until I saw a post mentioning this as a side effect to enclomiphene.

Just bringing this up as something to watch out for.
Click to expand...
At Denny's, you are entitled to the 55+ menu if you see more floaters than unhappy workers.
 
Wow - wish my endo hadn't been so lazy and stupid all those years ago .. these sound like very promising TRT treatments. Wonder if they'd work after suppressing my endogenous system for 17 years .. 😀
 
guster said:
How do you know its enclo and bot chlomid what alot of suppliers do?
Click to expand...
I do not DEFINITIVELY know. What I DO know is that:
1) On June 6, I had my testosterone and estradiol labs run for a baseline (403 and 25.4);
2) July 3 started clomiphene citrate through an online med spa;
3) July 29 had testo and estradiol labs run again and testo was 700 and estradiol nearly doubled to 48
4) Aug 5, stopped clomiphene and started enclomiphene from a trusted supplier;
5) Aug 29 ran labs again and testo was 896 and estradiol had dropped to 36

I haven't checked since but plan on running labs again Jan 26.

The continued rise in testo at the switch and the drop in estradiol, are exactly what one should expect with enclomiphene - but no - I have not had it tested - and again - I very much trust this particular supplier and I would not trust many if any others.
 
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mraajr said:
A month-ish ago I started taking Enclomiphene (12.5 mg ED). Total testosterone is up from 458 to 1100. Estradiol up from 18 to 41. Free testosterone is up from 63 to 190. The estradiol number is the one I am slightly concerned with, but given the ratio of total test/estradiol, I do not believe it to be too high. Though I have definitely noticed a slight increase in emotional response. Not anger or anything like that. Just that sappy videos and stories seem to make me a bit more emotional than I feel like they probably have in the past, if that makes sense.

It seems like no matter what peptide/drug, etc., I take, I respond extremely well to it. Does anyone think I should possibly cut the dose in half, or are these numbers relatively good? Just looking for some experiences other people have had on Enclo.
Click to expand...
Are you taking it as PCT or just to raise your T without steroids? Cause 1100 is alot!
 
mraajr said:
A month-ish ago I started taking Enclomiphene (12.5 mg ED). Total testosterone is up from 458 to 1100. Estradiol up from 18 to 41. Free testosterone is up from 63 to 190. The estradiol number is the one I am slightly concerned with, but given the ratio of total test/estradiol, I do not believe it to be too high. Though I have definitely noticed a slight increase in emotional response. Not anger or anything like that. Just that sappy videos and stories seem to make me a bit more emotional than I feel like they probably have in the past, if that makes sense.

It seems like no matter what peptide/drug, etc., I take, I respond extremely well to it. Does anyone think I should possibly cut the dose in half, or are these numbers relatively good? Just looking for some experiences other people have had on Enclo.
Click to expand...
Congratulations on success with the Enclomiphene!
Can I ask what age group you are in? I have read that the Enclomiphene has less effect on increasing the testosterone from the Leydig cells as you move up in age, and possibly will have no effect on men over ~50, obviously this is different for everyone.
signed: The Boogyman
 
yrrdead said:
Just had to stop. Started about the same time as Reta. Was dosing 12.5mg eod for first 6 weeks. Then bumped to every day. Last week started having some minor vision issues, which being old(44) I kind of dismissed until I saw a post mentioning this as a side effect to enclomiphene.

Just bringing this up as something to watch out for.
Click to expand...
Have you tested to see what your T came up to, and if so, what was your dosage prior to the test?
The Boogyman
 
Why enclomiphene or clomid over testosterone? Wouldn’t testosterone be the “cleaner” more “studied” way to raise testosterone? I understand why doctors prescribe enclomiphene. It’s not a controlled substance therefore less scrutiny in their prescribing practices if they use enclomiphene over testosterone . I’m just wondering if it’s the best option though for older men not wanting to preserve fertility? As I see it TRT negatives would be : raises hct/hgb, maybe increase PSA, worse sleep apnea, requires monitoring, is a controlled substance so harder to get, will effect fertility, and requires a commitment to stay on for the long haul once you start. The negatives for enclomiphene would be: suppresses the estrogen receptors which can lead to decreased CV protection, possible bone loss, loss of estrogen protection on the brain, loss of libido (estrogen has a big effect on libido for men), mood changes, much less studied, can raise SHBG which effects free T.

I guess at the end of the day if you’re an older man (mid 50’s and older) who doesn’t want to maintain fertility and wants the benefit of a well studied approach to treating declining testosterone , why wouldn’t you choose testosterone if given that option by a medical provider?
 
Jellybelly54 said:
Why enclomiphene or clomid over testosterone?
Click to expand...
Because enclo uses your own natural processing to create test whereas TRT does not and once you're using TRT, your natural ability diminishes.

Albeit, this only works for folks who are still able to produce SOME test. Mine was 400 prior to enclo. I wanted TRT. Doc told me I should try clomid/enclo first and let my body makes its own if it could. Mine can. Test is 750-850 - and all produced by my own body.

Won't work for everyone.
 
For the cardiovascular system, a steady test level is best. So enclo (with or without HCG) could be better in that regard, though test-u is also an option.

Another option is daily or EOD test-c. Playing with AI, it looks like daily, subq injections of test-c may be worth it.

Gemini said:
The "natural pulse" of Enclomiphene or hCG is often less stressful on the heart than the "sawtooth" of twice-weekly injections.

Comparison: Biological vs. Mechanical Stability
ProtocolStability ProfileMechanism of "Steadiness"CV Stress Impact
EnclomipheneNatural Circadian PulseMimics natural 24-hour cycle; highs in AM, lows in PM.Lowest; avoids supraphysiological spikes entirely.
hCG OnlyStimulated RhythmTriggers steady testicular output; lasts ~36-48h per dose.Low; maintain endogenous "backfill" hormones (DHEA/Prog).
Enclo + hCGHybrid BiologicalDual-pathway stimulation; creates a very robust, flat "floor."Low; best for keeping E2 high-normal for heart protection.
Test-C (Weekly)High-Amplitude SawtoothMassive peak at 48h followed by a 5-day crash.Highest; peak causes BP spikes and thick blood (HCT).
Test-C (2x/Wk)Moderate SawtoothSplits the "oil bolus" in two; reduces peak by ~50%.Moderate; much safer than weekly but still "pulsing."
Test-C (Daily)Mechanical Flat-lineEliminates peaks/troughs; mimics a constant drip.Lowest (Inj); prevents the "spike" stimulus for RBCs.
Test-U (Slow)Long-Term TaperThe "heaviest" ester; releases tiny amounts over weeks.Very Low; most consistent levels over months of time.
Click to expand...

Enclo can lower IGF-1, but most/many guys on enclo are already on GH.
 
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Zydeceltico said:
Because enclo uses your own natural processing to create test whereas TRT does not and once you're using TRT, your natural ability diminishes.

Albeit, this only works for folks who are still able to produce SOME test. Mine was 400 prior to enclo. I wanted TRT. Doc told me I should try clomid/enclo first and let my body makes its own if it could. Mine can. Test is 750-850 - and all produced by my own body.

Won't work for everyone.
Click to expand...
Do you feel like you get the full benefits of exogenous test with enclo? Been on enclo 6+ months. Went from 460 to 1100 total t, 90 to 140 free but estrogen jumped to 103. Started ai and last labs showed estrogen at 59 and free t went to 227. I personally have felt terrible almost the entire time I've been on enclo. But that is probably due to the fact that estrogen has been all over the place. Debating switching to test c just so I have more control over where I'm at. Already have 4 kids and recently got snipped so not worried about fertility. Trying to decide if I stick it out on enclo or just make the switch after my next provider visit.
 
Haven't tried enclomiphene just listened to podcasts and read about it. This is mostly anecdotal, but the guys that like it, like it. The guys that don't, there are two issues. Numbers look good on paper but no symptom relief and also it lowers igf1 levels.

Plus, there is no long term studies as opposed to testosterone that's been around for decades.
 
Calm Logic said:
For the cardiovascular system, a steady test level is best. So enclo (with or without HCG) could be better in that regard, though test-u is also an option.

Another option is daily or EOD test-c. Playing with AI, it looks like daily, subq injections of test-c may be worth it.



Enclo can lower IGF-1, but most/many guys on enclo are already on GH.
Click to expand...
I've seen a few sources talking about daily sub q test injections but haven't talked to anyone that is doing this yet. Most of my friends on test are just pinning IM twice a week and liking that. I've found I convert to estrogen quickly so wondering if subq would work better for me if I were to switch from enclo to test c.
 
mraajr said:
It is hard to speak on the water retention because I also take MK-677 and Tesamorelin, both of which can cause you to retain water. I do think I hold a bit of extra water weight, but I am unsure which of the three is causing it.

I have not gained any weight on it, but I am also in a pretty significant calorie deficit on Reta.
Click to expand...
Has the Mk-677 caused hunger spikes? How have you been managing that on calorie deficit and reta? My understanding is that you'd want to introduce that and tesa after you've finished hitting your target body comp.
 
Daily or EOD can supposedly help, as can subq. But being a little high on estrogen may be fine. The test:estrogen ratio (between 10:1 and 30:1) is more important than estrogen per se. The higher the test level, the more estrogen you need.

High-normal estrogen is good for the endothelium and for healthy lipids. That's one reason primo can be of the devil without HCG or religiously monitoring estrogen.
 
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mraajr said:
A month-ish ago I started taking Enclomiphene (12.5 mg ED). Total testosterone is up from 458 to 1100. Estradiol up from 18 to 41. Free testosterone is up from 63 to 190. The estradiol number is the one I am slightly concerned with, but given the ratio of total test/estradiol, I do not believe it to be too high. Though I have definitely noticed a slight increase in emotional response. Not anger or anything like that. Just that sappy videos and stories seem to make me a bit more emotional than I feel like they probably have in the past, if that makes sense.

It seems like no matter what peptide/drug, etc., I take, I respond extremely well to it. Does anyone think I should possibly cut the dose in half, or are these numbers relatively good? Just looking for some experiences other people have had on Enclo.
Click to expand...

I was on clomid before Test. Cyp., it more than doubled my levels but I still felt awful. Enclo. is supposed to be better in this regard but much of what's on the Gray market is supposedly Clomid. E2 is very beneficial for men unless you are having sides from it, so I never worry about it.

View: https://www.youtube.com/watch?v=qeS7j_JU1G4
 
My total testosterone was already 698 and I'm plenty old, I took 25mg of Enclomiphene for 3 months and checked it. Uhhhhhhh 1500+++ and Estradiol went from 35 to 128. I made the mistake of watching Titanic and Joy Luck Club on the same day. Anywho, I just went to 1 - 25mg a week and it took 9 months for it to come back down to TT 958 and Estradiol 58. I just went off of it for 6 months and just started back on it. Just paid $300 for 90 pills, so should last me a year and half.
 
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soapysnake said:
Do you feel like you get the full benefits of exogenous test with enclo?
Click to expand...
Let's put it this way...................... at 62 years old I began suffering from a weak willy, very weak. Severe ED. Something that I never had in my life. In fact, it was erectile dysfunction that REALLY sparked my journey with tirz believe it or not. I started enclo and tirz at the same time last June.

I am super, incredibly happy to report that my ED is absolutely, 1000% remedied. My lovely girlfriend is quite pleased with this also. So yes - lol - I feel like I am receiving the very full benefits - day after day, night after night - LOL
 
Zydeceltico said:
Let's put it this way...................... at 62 years old I began suffering from a weak willy, very weak. Severe ED. Something that I never had in my life. In fact, it was erectile dysfunction that REALLY sparked my journey with tirz believe it or not. I started enclo and tirz at the same time last June.

I am super, incredibly happy to report that my ED is absolutely, 1000% remedied. My lovely girlfriend is quite pleased with this also. So yes - lol - I feel like I am receiving the very full benefits - day after day, night after night - LOL
Click to expand...
lol this is amazing. If anything my enclo use and estrogen jumps were killing my sex drive. Glad to hear this helped you out though 😂
 
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