Endotoxins!

[Skydweller007]

So, who are the CN vendors that test for - or at the very least, guarantee against - endotoxin levels being too high? Additionally, I don’t understand how mass and purity are so prevalent in testing, but not endotoxins. Starting to see a lot of bad endotoxin tests pop up, so I’m wondering who’s out there that is doing the right thing with this?

 

[yrrdead]

Don't be confused this isn't like best manufacturing practices. This is pure macro economics. The market has essentially dictated mass and purity. So the vendors have responded with tests or the appearance of tests that the market has demanded. They aren't going to do anything beyond that.

 

[Dpkaymen]

The real problem in my opinion is the amount of failed sterility tests.

 

[CNCCurrency]

You are exposed to more germs touching a door handle. Herd immunity

 

[lasveganon]

I don't know of any that guarantee against anything more than mass and purity

 

[Airborne Daddy]

No one does and few pass sterility testing....

 

[RuggerPanda]

So, who are the CN vendors that test for - or at the very least, guarantee against - endotoxin levels being too high? Additionally, I don’t understand how mass and purity are so prevalent in testing, but not endotoxins. Starting to see a lot of bad endotoxin tests pop up, so I’m wondering who’s out there that is doing the right thing with this?

Janoshik has said samples almost never fail endotoxins and any that do are already reconstituted peptides and completely failed sterility testing. If sterility is a concern it’s best to just filter your peptides for peace of mind.

 

[hexagonal]

Endotoxins won't get caught in a filter from my understanding (though any bacteria that could produce endotoxins will), but they're also just not a concern for peptides based on the testing done.

 

[Lyophilized]

This is all about reducing risk, so my advise is always filter

 

[natalia99]

Janoshik has said samples almost never fail endotoxins and any that do are already reconstituted peptides and completely failed sterility testing. If sterility is a concern it’s best to just filter your peptides for peace of mind.

Can you say more about sterility testing? Newbie here. Do you mean they have bacteria present?

 

[Habibibi]

Read the FDA guidelines for acceptable levels of endotoxins. It's higher than you think it is. No vendor has failed endotoxin testing based on those guidelines.

 

[YoYoFat]

No one does and few pass sterility testing....

Eh?

While no vendors test for endotoxins, it’s palpably false to say few pass sterility. Spend time on FPPG and you’ll see those third party test results showing many pass sterility.

 

[YoYoFat]

This is all about reducing risk, so my advise is always filter

Filtering doesn’t remove endotoxins.