Global GLP-1 Guidance

[Nathanologist]

The World Health Organization yesterday issued its first-ever guidance on treating obesity with glucagon-like peptide-1 therapies, conditionally recommending the drug class for long-term use in nonpregnant adults alongside a healthy diet, regular exercise, and medical counseling.

The guidance comes as global demand for drugs mimicking the hunger-curbing GLP-1 hormone has surged since 2021, when regulators began approving Wegovy (brand name for semaglutide) for weight loss. US spending on GLP-1 agonists reached $71.7B in 2023, an over 500% increase from 2018, when the drugs were primarily used to treat diabetes. A monthlong course in the US can cost upward of $1K, and the WHO estimates GLP-1 therapies will be inaccessible to over 90% of the more than 2 billion people projected to be affected by obesity in 2030.

The WHO's guidance calls for expanded access through measures such as tiered pricing and urges strong oversight to curb the spread of counterfeit drugs.

 

[Gr33dyOctopus]

Well, lets focus on making them cheap enough everyone can get in on this in a safe and cost saving way

 

[Not_Your_Dad]

Well, lets focus on making them cheap enough everyone can get in on this in a safe and cost saving way

When there's money to be made by big pharma? We can hope 😛

 

[Varixdos]

When there's money to be made by big pharma? We can hope 😛

Naw, let's not.

 

[Nathanologist]

“If you buy drugs online, look for these warning signs: Websites that don't ask for health information and don't require a prescription, and when you receive the drug, spelling errors on the packaging or the substance looks cloudy when it should be clear.”

Those misspellings tho. 💀

 

[Not_Your_Dad]

“If you buy drugs online, look for these warning signs: Websites that don't ask for health information and don't require a prescription, and when you receive the drug, spelling errors on the packaging or the substance looks cloudy when it should be clear.”

Those misspellings tho. 💀

I get the cloudy if should be clear but the rest of it... how else is this gonna work when we buy from CN?

😎

 

[keangkong]

I get the cloudy if should be clear but the rest of it... how else is this gonna work when we buy from CN?

😎

There should be spelling errors on the package; they're coming from folks living in China. It's not like we're buying from Germany, where everybody is great at English. By the way, I recently learned the main reason why English spelling is so difficult: Words are generally spelled as they were pronounced at the time that spelling became formalized. That's about the time of Shakespeare. However, pronunciations were rapidly changing: We were in the middle of the great vowel shift.

 

[keangkong]

The World Health Organization yesterday issued its first-ever guidance on treating obesity with glucagon-like peptide-1 therapies, conditionally recommending the drug class for long-term use in nonpregnant adults alongside a healthy diet, regular exercise, and medical counseling.

The guidance comes as global demand for drugs mimicking the hunger-curbing GLP-1 hormone has surged since 2021, when regulators began approving Wegovy (brand name for semaglutide) for weight loss. US spending on GLP-1 agonists reached $71.7B in 2023, an over 500% increase from 2018, when the drugs were primarily used to treat diabetes. A monthlong course in the US can cost upward of $1K, and the WHO estimates GLP-1 therapies will be inaccessible to over 90% of the more than 2 billion people projected to be affected by obesity in 2030.

The WHO's guidance calls for expanded access through measures such as tiered pricing and urges strong oversight to curb the spread of counterfeit drugs.

Another way to reduce counterfeiting would be for drug manufacturers to charge reasonable prices.

 

[AndyPanda]

The GLP craze is great, but I think people are overlooking how food companies like nestle are actively looking for ways to bypass our favorite drugs with their own sneaky chemicals to make you crave again. Hopefully the drug companies can stay ahead of them for at least a few more years.