Glutathione - are the tablets on amazon the same as the CN vials?

[john_askins]

I ask because the vendor I'm purchasing from is $66 for 10x1500mg vials. But for $20 on amazon, there are 60x500mg pills. Could you, in theory, open the pills, put them in a vial, add BAC and use it?

 

[AndyPanda]

I ask because the vendor I'm purchasing from is $66 for 10x1500mg vials. But for $20 on amazon, there are 60x500mg pills. Could you, in theory, open the pills, put them in a vial, add BAC and use it?

No. They will have fillers that you shouldn’t be injecting and who knows what they have been exposed to.

 

[john_askins]

No. They will have fillers that you shouldn’t be injecting and who knows what they have been exposed to.

I sort of figured. And i'm assuming orally it doesn't work nearly as well since it has to be digested?

 

[Waclive]

I ask because the vendor I'm purchasing from is $66 for 10x1500mg vials. But for $20 on amazon, there are 60x500mg pills. Could you, in theory, open the pills, put them in a vial, add BAC and use it?

Absolutely not. It doesn't really work that way. I wish it did though, it would make things easier.

 

[cheaperseeker]

You can make liposomal glutathione by blending it with sunflower seed powder and distilled water. It makes it more effective when taken orally because it encapsulates the glutathione in fat molecules, protecting it from digestive breakdown.

 

[Airborne Daddy]

No. They will have fillers that you shouldn’t be injecting and who knows what they have been exposed to.

I ran 12 weeks of injectable. Now I'm running tb500 but in the spring I'll try the liposomal pill glutathione that's reportedly up to 90% absorption. I'd be happy with 50% cuz everyone has a liposomal for another 30 bucks but never any testing to back it up. Swear it's all bs.

 

[CNCCurrency]

Easier to just inject it and not worrying about it working or not. Could be just me?

 

[Calm Logic]

Easier to just inject it and not worrying about it working or not. Could be just me?

Oral NAC (or GlyNAC) along with oral liposomal glutathione may be superior to subq glutathione over the long term. Will post studies later.

I am injecting Korean glutathione now though with oral vitamin C, and have been taking oral NAC too sometimes.

 

[CNCCurrency]

Oral NAC
[td]Bioavailability[/td][td]Very low (less than 10%), due to first-pass metabolism in the liver.

 

[Calm Logic]

Oral NAC
[td]Bioavailability[/td][td]Very low (less than 10%), due to first-pass metabolism in the liver.

The first pass is actually how oral NAC works so well for the liver, essentially forcing the liver to produce glutathione, including for the rest of the body. NAC is the gold standard treatment for Tylenol overdose.

 

[CNCCurrency]

The first pass is actually how oral NAC works so well for the liver, essentially forcing the liver to produce glutathione, including for the rest of the body. NAC is the gold standard treatment for Tylenol overdose.

I see

 

[lessthanhalf]

I just want to second the post about GLYNAC. Everything I read indicated that glutathione molecules ( basically glutamine plus glycine plus Nac ) don't get through cell membranes that easily, so it is possible to increase cellular glutathione with injected glutathione, but taking precursors orally that do enter cells more easily is much more effective at raising cellular glutathione and especially if you are talking about getting it past the blood brain barrier into neurones.
There is much more solid evidence that N Acetyl Cysteine NAC raises intracellular glutathione levels as well as it in combination with Glycine. And even some actual human trial evidence that Nac or GlyNac suplementation have positive effects in humans. Doses are fairly high at about 7 grams of each per day .

 

[Calm Logic]

Both in theory and reality, 7 grams per day of oral NAC is way too high and would raise hematocrit too much. That's why the standard dose on supplement bottles is only 600 or 1200 mg per day and why I stopped using oral NAC at high does, after getting bloodwork back.

In general, glutathione is best for the short term and oral NAC is best for the long term. (In other words, glutathione is more like HGH for being more direct, and NAC is more sustainable like sermorelin.)

 

[Waclive]

I've been taking NAC everyday at 600mg for years now 😅

 

[cheaperseeker]

I've been taking NAC everyday at 600mg for years now 😅

What benefits have you noticed?

 

[Waclive]

What benefits have you noticed?

I don't ever get sick. My lungs don't burn when rucking at higher elevations. My family has a history of cardio events, so taking it for those benefits as well.

Something else that interest me is the research into the neurodegenerative diseases. It's also why I'm an advocate for nicotine via a safe consumption method.

 

[cheaperseeker]

I don't ever get sick. My lungs don't burn when rucking at higher elevations. My family has a history of cardio events, so taking it for those benefits as well.

Something else that interest me is the research into the neurodegenerative diseases. It's also why I'm an advocate for nicotine via a safe consumption method.

My lungs get sore easily ever since I had COVID, so I'd definitely benefit from support there.

 

[Waclive]

My lungs get sore easily ever since I had COVID, so I'd definitely benefit from support there.

It might be worth looking into the oral NAC and quercetin. It's two things on the list that I take everyday.

 

[Calm Logic]

Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function - PMC

Glutathione (GSH) is the most abundant endogenous antioxidant and a critical regulator of oxidative stress. Maintenance of optimal tissues GSH levels may be an important strategy for prevention of oxidative stress-related diseases. We investigated ...

pmc.ncbi.nlm.nih.gov

(2017)

These preliminary findings support the effectiveness of daily liposomal GSH administration at elevating stores of GSH and impacting immune function and levels of oxidative stress...

GSH increases were accompanied by reductions in oxidative stress biomarkers including decreases of 35% in plasma 8-isoprostane and 20% in oxidized:reduced GSH ratios

More info: https://pmc.ncbi.nlm.nih.gov/articles/PMC10075255/