Help me decide: Stay on Tirz, Switch to Reta, Stack Tirz & Reta, Stack Cagr & Reta?

[ColdSmoke]

I too am at seven months on Zepbound. At around 11.25 mg dose (55 units from 10mg vial) and have been very successful, I’m down 50lbs. Almost exactly 1.5 lbs a week.

That said, the FOMO around the glucagon agonist is real though. Would I be down 70 instead of 50 on Reta? I will probably hold off on the Reta until I have an actual plateau. The increased heart rate has me a bit tentative.

Now we have Elora and I think if I had to choose a non FDA approved weight loss med, I’d go with Elora based on what I’m hearing about it.

 

[lessthanhalf]

This is hard. I'm currently on 10mg tirz and have been on Tirz for about 7 months with awesome results. Been taking it prescribed but when the costs got too high I decided to go the gray way instead. So I decided to switch to Reta (not started yet). Then reconsidered and decided to stack tirz + reta. Now I read about Cagrilintide and looked in to stacking reta + cagr. Can't think straight anymore from all the alternatives 😭 any help and experiences would be hugely appreciated. Sorry if there's a thread almost like this one.

I think a good answer to this requires knowing the usual stats, like age, start weight, current weight, target, height, lifelong obesity problem or not etc? And side effects from tirz?

My first guess is if you are not that far from your target and do not have a lot of side effects, then the lowest risk approach is just stick with the tirz so long as you think there is a good chance of it getting you to your target at or before 15mg/w. Tirz has the lowest rate of side effects, Elora might even be better but only at low doses. So adding drugs adds to the risks of drug allergies and almost certainly more side effects than you currently have.

If you have a lot of weight left to lose, and think 15mg of tirz will not get you there, then adding in extras now or later makes more sense. In general the idea is to get the most or to target weight loss with the least side effects, and tirz is actually pretty good at that. Reta and especially cagri do have higher rates of adverse effects than tirz.