Hey over 50 ladies! Get in here, Let's talk

chunkyTN

GLP-1 Novice
Member Since
Dec 12, 2025
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Location
Nashville TN
United-States
As the title says I’m looking for input for other ladies over 50 who are on this pilgrimage (not a journey to me, that sounds too easy). I’m 59 and have been overweight since I hit puberty. Total hysterectomy at 44. No major health problems.

SW 322
CW 308
GW 200ish

I started December 15th on sema. I’m making decent progress. I’m up to .5 on dose but thinking about switching to tirz. I ordered a 30mg kit a while back. Going back and forth on changing and maybe doing a small sema kicker on my 3rd or 4th day each week if I need it. I have been having more cravings on day 6 and 7 each week.

I’m having trouble getting motivated to exercise. This happens to me every winter. I know that’s what it is. If I get my butt up and go to the gym I always feel better but depression is a killer to motivation. I’m on this mission alone. Nobody around me with time is interested in going with me so I’m gonna have to find that motivation alone. I did get a recumbent bike and some free weights and I’m trying to do that every day.

I've got my nutrition under control I think. Trying to hit the protein goal everyday but sometimes I miss. Making sure to get fiber every day and so far that has kept me and the toliet in good standing. I try to drink enough everyday but some days I feel like I'm gonna float off. I'm not counting calories because all the fatty foods I usually love is kinda gross to me right now. Plus after doing the calculation to see how many calories I would need to eat to maintain my weight I know I'm probably at half that amount. If you haven't done that yet, look it up.

I’m worried about the sagging skin! I’ve had so many surgeries in the last decade (mostly ortho stuff - back, hands, arm). I just got out of debt from having my gallbladder out but I consider that win with the GLP-1s. I know I’m not going to be a young hottie but I hate the idea of having to tuck and compress loose skin for the rest of my life or get it cut off.

Just looking for feedback from other mature ladies. Suggestions? Experiences you’re having?
 
I am right there with you. I've pretty much given my whole story in this thread --> here <-- in case you are interested. I just added reta after I got to 1mg of sema and just kept on taking both. There are already others taking both tirz and sema so I see no reason to do anything different (unless you get a troublesome side effect)

I am personally resigned to having loose skin but that doesn't mean I am not going to try and prevent it as much as possible. I am taking KLOW and drinking my water. I also moisturize in case that will help at all. I don't know if any of it is going to work but it couldn't hurt.
 
I am right there with you. I've pretty much given my whole story in this thread --> here <-- in case you are interested. I just added reta after I got to 1mg of sema and just kept on taking both. There are already others taking both tirz and sema so I see no reason to do anything different (unless you get a troublesome side effect)

I am personally resigned to having loose skin but that doesn't mean I am not going to try and prevent it as much as possible. I am taking KLOW and drinking my water. I also moisturize in case that will help at all. I don't know if any of it is going to work but it couldn't hurt.
I have read your posts and I was hoping you would reply. Have you started the KLOW? Noticing any results?
 
Hi, welcome & I hope your pilgrimage is going well!! I am 57, started on Sema in 2023, didn't expect it to work but BAM! I lost a lot of weight. SW 211, got down to 152 lbs. I have always worked out, for me, no one but me. I was never bigger than 180 (besides after having my kids) but after age 50, the weight just packed on. #menopause UGH!!! I thought I could manage without the Sema & stopped it for about 8 months. I gained 11 back so I got back on SEMA with no results, didn't work the 2nd time.

That is when I switched to TIRZ. Now, it is working well for me again. I would stick with SEMA, it is working for you. Don't switch until you stop getting results. You are only on 0.5mg, you can go up to 0.75, then 1.0 , 1.25, 1.50, 1.75 & up to 2.0 I believe. Give yourself some time. You are losing! Woo hoo!!

Everyone on every blog tells me to switch to Reta. I am not interested in switching to Reta because it is the new shiny toy. The Tirz is working for me so I am going to continue what is working.

*You also have to resign yourself to work out for YOU". No one is interested in working out with me either. I loved my Crossfit gyms but they kept closing, then there was OrangeTheory (too expensive), so I bought a beautiful Peloton bike. The Peloton bike is the best piece of exercise equipment I have ever owned. I LOVE it! I can do it every day if I want to, rain or shine. There is tons of other workouts too, yoga, weight lifting, walking (in the app, you can listen while you are out on your walk), running (no thanks), and rowing too. It keeps track of your calorie burn (on my apple watch) & all of my progress. Plus, if you keep track of your calories (which I do, in an app), then you see the calories that you burn and it shows the deficit. Then you lose more weight.

I know you are worried about the skin, but think of the pressure that the weight is putting on your joints. Your hips, knees, your back, etc. they will thank you, so will your heart, and blood vessels. Don't worry about the skin until it actually happens. You are putting the cart before the horse. Ha Ha!

You've got this. And just so you know, when I call my friends, the first thing they say is, "NO, I don't want to go for a walk with you!!" Ha Ha! I cannot be offended, it just means I am persistant. I finally found a group of friends that DOES walk with me every weekend but if they can't go, I am still going to go without them. You have to rely on yourself to do it.

No go get 'em!! Keep us posted on your progress. 🙂
 
Was skinny all my life until I had my hysterectomy at 43. No matter what I did, my weight kept going up. This pushed me into body dysmorphia and I couldn't even look at myself in the mirror. I did OrangeT up to 4 times a week and nothing. I just could not lose weight. I could not take Sema, horrible side effects. Took Triz for about 6 months and lost about 11lbs. I stopped taking Triz for several months and a friend told me about Reta. Started Mid Aug and I am now down 50lbs. Reta has worked for me where other GLPs did not. I agree with others, do what works for you! 215 to 165.. I'd like to lose another 20. Not fond of the lose skin either but I feel better in my own skin and my shoulder and joint pains are less. I no longer have to take blood pressure meds and my cholesterol is down.

This christmas was the first time someone took a photo of me that I didn't cringe at seeing myself and actually thought I looked pretty cute for 56 🙂 Good luck and welcome to this forum. Lot of great info and some really nice people too.
 
I have read your posts and I was hoping you would reply. Have you started the KLOW? Noticing any results?
Oh yeah, I've been taking that for a while. I can't really say if it is doing anything to prevent or reduce sagging skin but I can say it has eliminated back pain and significantly reduced the pain in my knees. That alone makes it worth taking.
 
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