How much do peptides deteriorate?

[Lullabytreehugger]

After reconstituting my 30mg vial of tirz and keeping it in the fridge at all times, how long do I have to use it up?

Do all peptides last the same? Like reta and sema and cagrilintide?

What happens if I used after 3 months?

When I went on holiday January of this year I had a long 3 months holiday. At the time I didnt know anything about buying from China so all my stuff was legit.

I took with me 8 pens of Ozempic with me kept in a cooler bag with frozen ice packs (so during my plane ride it was kept very cold).

Now ozempic is already reconstituted so you just select your dose and inject yourself. So how come my ozempic never deteriorated?

Is there a difference between original ozempic and grey market sema?

Forgive my ignorance I really dont know the answer…

 

[rkl123]

After reconstituting my 30mg vial of tirz and keeping it in the fridge at all times, how long do I have to use it up?
1-3 months depending on how much you trust your BAC. 1 month is harder guarantee.
Do all peptides last the same? Like reta and sema and cagrilintide?
We don't have good data on this.
What happens if I used after 3 months?
Mild risk of infection (bacteria) + small amount of degradation.
When I went on holiday January of this year I had a long 3 months holiday. At the time I didnt know anything about buying from China so all my stuff was legit.

I took with me 8 pens of Ozempic with me kept in a cooler bag with frozen ice packs (so during my plane ride it was kept very cold).

Now ozempic is already reconstituted so you just select your dose and inject yourself. So how come my ozempic never deteriorated?
There are preservatives in Ozempic. Plus it probably did deteriorate a little.
Is there a difference between original ozempic and grey market sema?
Preservatives
Forgive my ignorance I really dont know the answer…

 

[Biglemon]

Any guesses as to what those preservatives are? Seems like that wouldn’t be too hard to discover/test since there are so many GLP-1 contenders now, brand and off-brand.

 

[Lullabytreehugger]

What are these preservatives? Why cant the chinese vendors add the same preservatives?

 

[Sandwitch]

Any guesses as to what those preservatives are? Seems like that wouldn’t be too hard to discover/test since there are so many GLP-1 contenders now, brand and off-brand.

According to HIMS for their compounded semaglutide: Inactive ingredients are Disodium hydrogen phospate dihydrate, sodium chloride, benzyl alcohol, hydrochloric acid, sodium hydroxide, water. Most of these are to buffer the pH within a certain range. Benzyl alcohol is a common preservative found in these formulations.

 

[penewbie]

According to HIMS for their compounded semaglutide: Inactive ingredients are Disodium hydrogen phospate dihydrate, sodium chloride, benzyl alcohol, hydrochloric acid, sodium hydroxide, water. Most of these are to buffer the pH within a certain range. Benzyl alcohol is a common preservative found in these formulations.

Benzyl alcohol is the BAC part of BAC water.

 

[scarywood75]

They do add preservatives in the lyophilized powder already, mainly the filler that's there to slow down degradation, protect from temp swing, etc. Not everything can be added at that process tho.

I'd say it's good for a month, if it's in a single use vial maybe a bit more.

You can make your own reconstitution solution to replace BAC water if you want more protection and a longer shelf life