If you were a newb... would you start with Tirz or Reta first?

[LetsMakeMayhem]

**Not Asking for Medical Advice**
**Asking for personal perspectives only**

Hi All,
For those that have been on the weight loss journey with GLP-1s, if you had to start over all over again would you go with Triz or Reta as your first GLP?

Personally, I am thinking about starting Triz first and then moving on to Reta at a later time. Someone told me to "keep my options open" in case my progress stalls on one peptide so that I have still have other options. I know each of our bodies are different and we may not have the same experience on the same peptides, but just trying to figure out a great starting point.

Additionally, how you do feel about me stacking Amino 5 1 MQ while starting my first GLP? This was some information that was told to me by multiple people (as to avoid losing muscle mass, though I am exercising and doing cardio already).

Keep in mind, I've been a fata*s my whole life, even as a child. My metabolism is just garbage and needs some help. I've lost over 60lbs+ on diet changes and cardio alone, but I haven't been able to get the rest of this off. Thanks in advance for your insight

 

[indolent]

Have you first used the search function at the top, and the table of contents under the top-level Forums tab?

 

[LetsMakeMayhem]

Yes, but didn't locate exactly what I was looking for. I located general information about Reta raising HR and RHR but that is about it.

Maybe I'm not finessing the search filters good enough.

 

[penewbie]

Tirz.

 

[AndyPanda]

**Not Asking for Medical Advice**
**Asking for personal perspectives only**

Hi All,
For those that have been on the weight loss journey with GLP-1s, if you had to start over all over again would you go with Triz or Reta as your first GLP?

Personally, I am thinking about starting Triz first and then moving on to Reta at a later time. Someone told me to "keep my options open" in case my progress stalls on one peptide so that I have still have other options. I know each of our bodies are different and we may not have the same experience on the same peptides, but just trying to figure out a great starting point.

Additionally, how you do feel about me stacking Amino 5 1 MQ while starting my first GLP? This was some information that was told to me by multiple people (as to avoid losing muscle mass, though I am exercising and doing cardio already).

Keep in mind, I've been a fata*s my whole life, even as a child. My metabolism is just garbage and needs some help. I've lost over 60lbs+ on diet changes and cardio alone, but I haven't been able to get the rest of this off. Thanks in advance for your insight

If I were starting all of this again, I would take Semaglutide first. It’s super cheap, and to me it has no effect after being on Tirz. I would do Sema, Tirz than Reta.

I would not start different peptides at the same time. Take one to see how it works and then try another of you feel like you need it.

 

[Peptidase]

Would start with Reta. Especially with being potentially GLP-1 naive. Works great and the side effect profile is a lot less in my experience than the others. Used Tirz to start but stopped after about 5 weeks (constipation, ridiculous insomnia, anhedonia). With Reta, I’ve largely had none of those problems. And the weight loss was a lot faster with it.

 

[touringsedan]

Semaglutide first, cheapest, has the most sides (which help some with effectiveness). Tirzepatide and eventually Reta if needed. This gives you the most options of/when one stops being effective.

 

[flsailfish22]

I personally chose to start on reta. I did have some side effects, but switched to micro dosing 3 days a week those side effects are gone. 2 months in I'm only on 3mg. I take 1mg M, W, F. Sometimes I have slight food noise, but I'm ok with that. Eventually, you will have to learn to eat without extra help. Days I have food noise are also the same days I haven't had enough water and fiber. I view GLP1s as a tool and not a crutch I can't live without.

 

[miche52]

**Not Asking for Medical Advice**
**Asking for personal perspectives only**

Hi All,
For those that have been on the weight loss journey with GLP-1s, if you had to start over all over again would you go with Triz or Reta as your first GLP?

Personally, I am thinking about starting Triz first and then moving on to Reta at a later time. Someone told me to "keep my options open" in case my progress stalls on one peptide so that I have still have other options. I know each of our bodies are different and we may not have the same experience on the same peptides, but just trying to figure out a great starting point.

Additionally, how you do feel about me stacking Amino 5 1 MQ while starting my first GLP? This was some information that was told to me by multiple people (as to avoid losing muscle mass, though I am exercising and doing cardio already).

Keep in mind, I've been a fata*s my whole life, even as a child. My metabolism is just garbage and needs some help. I've lost over 60lbs+ on diet changes and cardio alone, but I haven't been able to get the rest of this off. Thanks in advance for your insight

**Not Asking for Medical Advice**
**Asking for personal perspectives only**

Hi All,
For those that have been on the weight loss journey with GLP-1s, if you had to start over all over again would you go with Triz or Reta as your first GLP?

Personally, I am thinking about starting Triz first and then moving on to Reta at a later time. Someone told me to "keep my options open" in case my progress stalls on one peptide so that I have still have other options. I know each of our bodies are different and we may not have the same experience on the same peptides, but just trying to figure out a great starting point.

Additionally, how you do feel about me stacking Amino 5 1 MQ while starting my first GLP? This was some information that was told to me by multiple people (as to avoid losing muscle mass, though I am exercising and doing cardio already).

Keep in mind, I've been a fata*s my whole life, even as a child. My metabolism is just garbage and needs some help. I've lost over 60lbs+ on diet changes and cardio alone, but I haven't been able to get the rest of this off. Thanks in advance for your insight

Sema then tirz. I lost a bit over 30 (194 to 161) pounds on sema, highest dose 1.0mg. It was slow but it came off. I went to maintenance for awhile. It gave me a chance to manage where I was. I switched to tirz 4 weeks ago currently dosing at 3.0mg. Gonna continue to microdose to get to 145 pounds. Would like to try reta but the racing heart side effect gives me pause.

 

[Ted R]

I chose Reta as well, but experienced the dreaded Resting Heart Rate increase side effect (jumped from 68 to 120), so loving Tirz now.