Is Tirz even something I should consider for 10-15lbs?

[squig33]

My understanding is that these drugs are created for long term use, and I have read that generally people who need GLP-1 drugs are very likely to need to continue them for long term treatment. This is a very personal decision for everyone. I would not take something like this for short term 10-15lbs but you do you.

From ChatGPT with source links:

Clinical trials investigating tirzepatide, a dual GIP and GLP-1 receptor agonist, have primarily focused on its long-term use for managing type 2 diabetes and obesity. For instance, the SURPASS-4 trial evaluated tirzepatide over a 104-week period, demonstrating sustained reductions in HbA1c and body weight compared to insulin glargine. (Lilly Medical) Similarly, the SURMOUNT-1 trial assessed tirzepatide's efficacy in weight management over 72 weeks, with findings indicating significant weight loss and a reduced risk of progression to type 2 diabetes. (Endocrinology Advisor). Regarding short-term use, data are limited. A follow-up analysis from the SURMOUNT-1 trial noted that 17 weeks after discontinuing tirzepatide, participants experienced modest weight regain and increases in HbA1c levels, suggesting that the benefits of tirzepatide may diminish upon cessation.(Science Daily) This underscores the potential necessity for ongoing treatment to maintain therapeutic effects.

 

[BrowsingAbout]

Hell yeah, why not? If it makes it easier to achieve your goals, imo I say do it. Fuck anyone else or their opinions. We're only here ~70 years, why struggle harder with anything than you have to? It's such a weird mindset to have. If an easier road is available, i personally think its fucking stupid to not take that. Pride/ego/shame/fear/etc. are the bane of our existence.

I’m with this! DO IT!

 

[BrowsingAbout]

I had 15 stubborn pounds that would not come off - no matter what diet or exercise. I’m also a binge eater and have always had issues with that. My psych suggested a GLP1. I found tirz and lost 20! Happy and healthy!! And SO thankful!

 

[Allfornat]

Why not? I used it to get rid of my 5lb menopausal weight I could not lose working out or eating healthy! It worked!!!!

 

[Dee X]

5'10" at 145 pounds sounds too thin. i'm the same height and at 165 i had people telling me i didn't look good.

it's a very unpopular thing here but, i use fat melting injections to target the areas where the fat might never go away.

i'm guessing your head is going to look too gaunt once you go that low.

I'm at 161 right now, heading down to 150.

What's crazy is that going off of BMI alone, 129 is still within range of healthy. I can't imagine how unhealthy we would look at that weight.

 

[raw_oyster_eater]

I'm at 161 right now, heading down to 150.

What's crazy is that going off of BMI alone, 129 is still within range of healthy. I can't imagine how unhealthy we would look at that weight.

it'd be nice to see some picts of people but there are some who think they have a god given right to steal and alter your photo ( put your head on whatever) if they get mad at you.

 

[Dee X]

it'd be nice to see some picts of people but there are some who think they have a god given right to steal and alter your photo ( put your head on whatever) if they get mad at you.

I'm sorry you had a falling out with your homie.

 

[raw_oyster_eater]

I'm sorry you had a falling out with your homie.

but me and you still love each other so i'm still all good.

 

[AndyPanda]

What were those fat melting injections?

Lemon Bottle

 

[Superfluous]

Lemon Bottle

Where do you get your supply? The wife is interested in this but apparently a lot of fake stuff goes around Europe.

 

[MingHenry]

I gained a lot of weight from antidepressants and college. No longer on antidepressants. Dropped most of it the last 2 years. Went from about 230 peak weight to just recently breaching the 160 mark as a 5’10 dude with some muscle mass.

I know it probably sounds like I am skinny already at that weight, but I would estimate I’m somewhere in the 16% bodyfat range and just look generally unimpressive with a flubby gut and love handles. As I’ve gotten skinnier the weight has gotten more stubborn and I’ve been meticulously calorie tracking and getting 10k steps, but the final 10-15 pounds I’m looking to lose to get shredded has been very difficult.

I eat high protein (150g+ daily), strength train 3-4 times a week, and cardio daily. I don’t doubt I could do it naturally, but I feel like throwing Tirz at it would just make it less of a ‘battle’ as the biggest thing I struggle with is constant hunger, and it just takes a mental and physical toll to try and ignore my body telling me to eat.

Is doing 2.5-5mg for 2ish months to just finish the job and then maintain worth it? I’m no stranger to drugs and biohacking, I’ve messed around with some SARMs and Anavar before. Dealt with the whole mental piece of ordering grey market research chemicals from china and then putting it into my body. More just asking if the peptide itself is practical for this purpose. Anyone else used short term for vanity weight loss/bodybuilding purposes? Should I just suck it up and finish the job naturally?

I think before you start tirz - and I have no issue with how you want to use it, but as people have noted, the weight likely might return if you don't keep using it - maybe look into some other weight loss/metabolism peps - like tesa, tesa/ipa, tesa/ipa/cjc, AOD, also tesofensine, which is a pill. You might get where you want to go without tirz.

 

[Mewtwo]

Thanks everyone for your input, I’ve read and considered everything. Talked with another guy on Reddit who has used glp1 for this exact purpose with great success Ended up ordering a 5mg sema kit and will give it a whirl.

 

[scarywood75]

Hate however you want, but my theory is if you can't lose weight without the med, then you're gonna gain it back once you stop.

It's because you'll slowly adapt back to how you were before. It may not be instant, but you'll slowly start eating more calories and by the time you realize these 15 pounds are back.

Obviously you could just restart the med worse case no big deal, I'm just giving a heads up to what will most likely happen. My advice would be to stay on a low dose forever, but you can definitely try for yourself.

 

[scarywood75]

And no judgment here btw, I took it personally because yeah I could've put more effort toward weight loss and achieve the same without it, but I want to put my efforts in other things on my life, so I picked the easier route for my weight loss.

We are in a era with infinite tools, if you can achieve your goals with less efforts and focus on other areas of your life with GLP1, by all mean go for it!

 

[scarywood75]

I too didn't have much to lose, about 50lb and I'm almost there, it's a tool and not just for people that NEEDS it, but also for those that WANTS it

 

[scarywood75]

When people judge you for going the easier way, remind them that :
- they take their car to go to the grocery that's 5 mins away.
- they job hopping for a better pay
- they buy your vegetables instead of growing them
- so on.

Trust me they get quiet pretty quick lol

 

[hexagonal]

I gained a lot of weight from antidepressants and college. No longer on antidepressants. Dropped most of it the last 2 years. Went from about 230 peak weight to just recently breaching the 160 mark as a 5’10 dude with some muscle mass.

I know it probably sounds like I am skinny already at that weight, but I would estimate I’m somewhere in the 16% bodyfat range and just look generally unimpressive with a flubby gut and love handles. As I’ve gotten skinnier the weight has gotten more stubborn and I’ve been meticulously calorie tracking and getting 10k steps, but the final 10-15 pounds I’m looking to lose to get shredded has been very difficult.

I eat high protein (150g+ daily), strength train 3-4 times a week, and cardio daily. I don’t doubt I could do it naturally, but I feel like throwing Tirz at it would just make it less of a ‘battle’ as the biggest thing I struggle with is constant hunger, and it just takes a mental and physical toll to try and ignore my body telling me to eat.

Is doing 2.5-5mg for 2ish months to just finish the job and then maintain worth it? I’m no stranger to drugs and biohacking, I’ve messed around with some SARMs and Anavar before. Dealt with the whole mental piece of ordering grey market research chemicals from china and then putting it into my body. More just asking if the peptide itself is practical for this purpose. Anyone else used short term for vanity weight loss/bodybuilding purposes? Should I just suck it up and finish the job naturally?

Central fatness and risk of all cause mortality: systematic review and dose-response meta-analysis of 72 prospective cohort studies

Objective To quantify the association of indices of central obesity, including waist circumference, hip circumference, thigh circumference, waist-to-hip ratio, waist-to-height ratio, waist-to-thigh ratio, body adiposity index, and A body shape index, with the risk of all cause mortality in the...

www.bmj.com

Body fat and risk of all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies - PubMed

PROSPERO (CRD42021240743).

pubmed.ncbi.nlm.nih.gov

From a health perspective, you're already where you need to be if you're indeed at 16% bodyfat - all cause mortality doesn't start increasing until the mid 20%s for men. (There's actually a J shaped curve where continuing to drop bf% increases all cause mortality risk but this is likely confounded by people that have very low bf% due to disease skewing the risk)

 

[zpped]

Hate however you want, but my theory is if you can't lose weight without the med, then you're gonna gain it back once you stop.

It's because you'll slowly adapt back to how you were before. It may not be instant, but you'll slowly start eating more calories and by the time you realize these 15 pounds are back.

Obviously you could just restart the med worse case no big deal, I'm just giving a heads up to what will most likely happen. My advice would be to stay on a low dose forever, but you can definitely try for yourself.

The vast majority of people that lose weight with any method gain it back.

 

[scarywood75]

The vast majority of people that lose weight with any method gain it back.

Yeah spot on

 

[hexagonal]

Reading through the rest of the thread:

I think you've already made up your mind and are going to do what you're going to do. And that's fine. You're an adult so make your own choices.

But... Estimating your BF% isn't particularly accurate. Most measurements aren't particularly accurate. The only thing that is really accurate is medical imaging - CTs and MRIs. DEXA scans still can swing in accuracy in individuals by up to 10%, though errors are reduced in larger sampling populations, which is why they're still good for studies. It's still going to be better than an estimation, though, so I'd really recommend getting one if you want to have a better idea of what your BF% is. Even the picture doesn't tell us much - people carry fat so differently that there's not much to go off of.

Here's where I'm going to go out on a limb and you can feel free to tell me to screw off: I don't think losing 10-15lb is going to get your the body image you're after, particularly if you are at 16% BF. Plenty of people bulk in the teens, and the closer to 10% you go, the more likely you are to have it impact your testosterone, cortisol, energy, etc. levels and have it negatively impact your muscle gains. Some people don't see any of this until sub 10%, some people see it sub 15%. It's hard to tell what your muscle gaining potential is in general with you being in such a large caloric deficit, so I might actually recommend trying recomp or even bulking starting from where you are - you're in range for getting some of the best potential for gains, and while you won't have the same physique during the process as you would with a slow bulk from 10%, you're going to remove more confounding factors if you find you're not gaining muscle at the rate you think you should be. And a few extra pounds of muscle aren't going to be a night and day difference when it comes to burning calories, but they will provide a bit of a boost, and you might find it easier to get to the BF% you want.