GLP-1 Forum

Maintenance dose - transition

wkndworrier

GLP-1 Novice
Member Since
Aug 4, 2025
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USA
I am really happy with my results so far. I've only been on Retatrutide since late July and I think I'll be at my goal body comp in a month, max. I'm currently doing 2mg every 3.5 days. I previously had some increased skin sensitivity for a few weeks, but now I have zero negative side effects. Was losing a very steady 1-1.5 lbs per week. Maintained all strength.

Question for those of you who hit your goal - did you completely stop? Taper to a lower dose? Immediately transition to a lower dose? Has anyone had success with a very low "microdose"? .5mg or less only once per week?
 
I am really happy with my results so far. I've only been on Retatrutide since late July and I think I'll be at my goal body comp in a month, max. I'm currently doing 2mg every 3.5 days. I previously had some increased skin sensitivity for a few weeks, but now I have zero negative side effects. Was losing a very steady 1-1.5 lbs per week. Maintained all strength.

Question for those of you who hit your goal - did you completely stop? Taper to a lower dose? Immediately transition to a lower dose? Has anyone had success with a very low "microdose"? .5mg or less only once per week?
I stayed at the dose I was on. It kinda fell around where I feel I should be weight wise. I know If I lower I will devour sweets again. At my current dose I do get hungrier than I did when I was slowly increasing. I do get full and can stop myself. I do get sweet cravings but it's nothing like before. Usually something small or just some carbs can curb it. For me these are lifetime meds. Hopefully will always have affordable access.
 
For maintenance, I went from Tirz 15mg 1x weekly, transitioned to Reta 1mg once I titrated Tirz to 10mg (in 2 weeks). Added Cagri .250mcg to my Reta 1mg. Titrated Reta to 2mg, then 3mg. 3mg Reta & .5mg Cagri is my current maintenance with no plans to increase ( 1x per week). May decrease both over time if advantageous. No issues, weight stable( though I lost 4 lbs over last 4 months, unintended). I posted this before somewhere, but can't recall which forum.
 
I am super curious about maintenance dosing on Reta as well. I am about 3lbs from my GW but the research I have found hasn't been super helpful, especially since my Reta dose is fairly low (3mg weekly). Will definitely check out the video above but would love to keep this conversation going!
 
I haven't gotten to the stage where I'm going to maintenance yet, but I did watch a video from this guy who went through it. You might find it helpful.

View: https://www.youtube.com/watch?v=pKO6dQ89nIw
Thanks for the video. Once I got over how he used units instead of mg for his dose it was really interesting. Even though maintenance is still 10-15 lbs away I do think about what it will look like and if Reta is the right choice or if “down shifting” to Tirz might be better.

Happy to know I’m not alone in my challenges getting protein too but wish I had his discipline in getting it. I know I should but fall way way short too often.
 
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