Went down a research rabbit hole yesterday and came across AI reference to a finding that said reconstituted MOTS-C left at room temp for 2-3 hours could have a potency-loss of 80-90%. Looked a little further and it does have methionine and tryptophan in its sequence which apparently are 2 of the 3 peptides most prone to oxidation at room temp.
I don’t have anywhere near the scientific knowledge to judge the validity of that or the interest in looking at the sequencing of all the other common peptides out there, but wondering if those who do know better have an opinion on this or a suggestion based on that what other peptides would be most susceptible to this? I travel a lot and while I have an insulated case with a solid ice pack that works well, sometimes it’s just too long before I can get to a fridge and my peps are occasionally close to or at room temp for a bit, would love to know which ones would be better off left at home lol.
Also could this explain some of the disparity in experiences people have had with MOTS-C? For anyone that hasn’t felt much or anything while taking it, was it possibly at room temperature for a bit and that could be the cause? If a couple hours loses 80-90% I’d imagine even 30-40 minutes would have some significant effect, especially if dosing was already on the lower end
I don’t have anywhere near the scientific knowledge to judge the validity of that or the interest in looking at the sequencing of all the other common peptides out there, but wondering if those who do know better have an opinion on this or a suggestion based on that what other peptides would be most susceptible to this? I travel a lot and while I have an insulated case with a solid ice pack that works well, sometimes it’s just too long before I can get to a fridge and my peps are occasionally close to or at room temp for a bit, would love to know which ones would be better off left at home lol.
Also could this explain some of the disparity in experiences people have had with MOTS-C? For anyone that hasn’t felt much or anything while taking it, was it possibly at room temperature for a bit and that could be the cause? If a couple hours loses 80-90% I’d imagine even 30-40 minutes would have some significant effect, especially if dosing was already on the lower end
