My Reta turned off!

[BigDap50]

Ok, let me give you guys a quick run down; I am hoping that someone can offer some intel. I started Reta at 2 milligrams per week and it did not really have much of a effect at all. After 3 weeks, I decided to bump it to 4 mgs a week split into two doses. We got some serious traction at that point; my hunger was seriously suppresed and I lost about 12 pounds in 4 weeks. At week 3.5, the appetite suppression fell to the ground, but I held out for the additional week for the whole month. This week, I went to 6 milligrams split into two doses going to get lift off again but I have had zero change. My appetite is still there and the food noise is continual. Is this normal for this compound? Is there something I am doing wrong? I appreciate any help in advance.

 

[GLP1Pharmacist]

I stick with a once week dosing, no real evidence to support 2x week split from what I have seen or only way I would split is if there are issues tolerating.. I went up to 12mg and very happy.

 

[spyke65]

If your goal is weight loss, split dosing may cause you to end up using more reta to get the same effect as a single weekly dose. Why? Because the half-life is about 6 days. Your max dosage is below the beginnings of therapeutic levels (most report seeing results at 6mg or more weekly) consistently throughout the week, versus the same amount weekly. Instead of upping your total weekly dosage, try month at 6mg weekly.

 

[BooneDonk]

Above is my experience. Stick with weekly dose of your total. Makes a huge difference.