Opinion/anecdote: Don't be afraid of increasing your dose

From everything I've gathered, the most important thing is to stay at the lowest effective dose for as long as possible. It's better for the wallet and so you don't plateau as quick. I'm not sure how this recommendation differs from someone who is actively working out VS someone who hasn't gotten to that stage in their journey.
 
There are people who experience good initial weight loss with 1 mg of reta. I can't imagine, but everyone is different.

For tirz, a therapeutic dose is considered 5 mg by the drug companies (one third of the max dose). So I try to get at least 5 mg now. For starting tirz, many people I know couldn't wait to go from 2.5 mg to 5 mg.

My internist seems to think almost everyone should try to get to the max (15 mg of tirz). But I have had bad sides at 7.5 mg, even after being on 12.5 mg briefly.
 
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Too bad this is in the Reta section, only. Titration choices are a big deal for folks in general. (IMO) I like the terms like easy responders and resistant responders. Me being thick/dense skinned squatch. My doc, being the opposite. Im just glad he understands this. My scale didn't move for 120+ days. If that doesn't mess with your head. . . .
So give us thick folks a break too. 2 months to double check. 2 more months to slowly titrate up. This post better not have jinxed it.😡
 
Since it seems like my thoughts are being misrepresented and made into skillfully dispatched strawmen, I want to clarify one thing; I specifically said: increasing dose (assuming side effects are tolerated) is going to help people trying to deal with obesity (the people the drug was meant for) provided that the doses and the titration are in line with the clinical trials.

I did not and am not advocating for recklessly blowing up your dose as quickly as possible. I was only ever advocating for following the titration schedules and doses that the late stage clinical trials and medical researchers with MD/PhDs are using, as well as the titration schedules that are currently being used for drugs like tirzepatide, which is prescribed by doctors. I am not saying to go up 2mg a week, I am not saying to start at 6mg, I am merely advocating for following what the actual medical people are doing (assuming side effects are tolerated). This is not even considering that in fact the researchers felt confident enough to start some people at higher, and even the maximum doses for the sake of the trials, which I would personally not suggest.

If this disturbs you, and you feel COMPELLED to warn against any dose besides .5mg, I am not sure what to tell you, other than if it works for you, I am happy for you.

Side note: I would obviously advocate for doing all of this under the close supervision of a doctor, which I would of course suggest for even gray sema or tirz, but as this is an unapproved research chemical, I can only say that I would do it as long as you feel comfortable telling your doctor you are doing something fairly outside of the box.
 
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