People who switched from Tirz to Reta, how are you finding it?

[Big Rossatron]

I posted an log/update of sorts in this thread, admittedly I'm not at the max dose of Reta.

I saw a lot of people were switching and wondered if anyone went back, or if they'd preferred Reta and why?

 

[deleted.user.17]

I prefer reta because i had annoying constipation on tirz. But reta seems to make me kinda cold and i have a bit of allodynia on my arms. I can eat more normal meals without getting sickeningly full and still losing weight steadily.

 

[joseblo]

I posted an log/update of sorts in this thread, admittedly I'm not at the max dose of Reta.

I saw a lot of people were switching and wondered if anyone went back, or if they'd preferred Reta and why?

I like the ability to eat more and more variably with ejoyment. With Tirz we had to schedule days of enjoyment on the weekends right before pinning. Now most days I can enjoy something moderate and without TOO much food noise at constant weight.

However, inflammation is definitely still not as controlled, and I might go back to Tirz just for that. Perhaps at a lower dose (5-6mg/week) and with Survo to keep maintenance. I don't know that I would have chosen Reta for significant weight loss based on my Tirz experience, but I've never had to go very high with Reta (6mg/6days likely moving to 7mg/week).

 

[nogainz]

I've been titrating off Tirz, which I was only on for a month before starting the slow switch to Reta. Started Reta 1mg MWF, then titrated Tirz down to once weekly at 7mg (keeping the 10mg overall load I had when taking Tirz).

Now doing 2.2mg Reta MWF then 3mg Tirz Sat. Eventually will likely hold as long as comfortable at 3mg MWF Reta only. Steady 1.5-2lb weekly weight loss. Dexa scan end of this month so I can see how the visceral fat has gone down. Been stacking with Tesamorelin so between that & Reta I would think there will be reasonable reduction in VAT, but we'll see.

 

[Big Rossatron]

I like the ability to eat more and more variably with ejoyment. With Tirz we had to schedule days of enjoyment on the weekends right before pinning. Now most days I can enjoy something moderate and without TOO much food noise at constant weight.

However, inflammation is definitely still not as controlled, and I might go back to Tirz just for that. Perhaps at a lower dose (5-6mg/week) and with Survo to keep maintenance. I don't know that I would have chosen Reta for significant weight loss based on my Tirz experience, but I've never had to go very high with Reta (6mg/6days likely moving to 7mg/week).

However, inflammation is definitely still not as controlled

I think this is what is causing a lot of my problems, I have some water retention, a little lower back pain, some swollen ankles. Nothing really serious but enough that I want to do something about it.

Is there anything I can stack with Reta or is going back to Tirz the better of the two options? I didn't really struggle with any bad sides and I went up to the max dose, but it was getting crazy expensive.

 

[joseblo]

I think this is what is causing a lot of my problems, I have some water retention, a little lower back pain, some swollen ankles. Nothing really serious but enough that I want to do something about it.

Is there anything I can stack with Reta or is going back to Tirz the better of the two options? I didn't really struggle with any bad sides and I went up to the max dose, but it was getting crazy expensive.

From the reading I've done (recommend looking yourself), the anti-inflamitory effects come from GLP1 (not GIP or Glucagon) agonists. Reta is very low in that relative to Tirz. You could stack Sema with Reta, if you're comfortable with that sort of thing (two peptides that hit the same receptor), or you could stack Survo with Tirz (search for "ghetto reta"), Cagri and others. There's too many to choose from (Maz etc).

 

[tallclarknhandsome]

Was on mounjaro pen for a month (2.5mg), decided it was too expensive. Started reta .5mg per week at the same time. Didn't have any side effects until last weekend. Was on the toilet for 3 days straight, I think it all caught up to me. I'll probably take the golden dose from the tirz pen wait a week and start back on the reta at 1 mg. I'm having really good appetite suppression and fat loss on low dose.

 

[vewdew34]

I am at 8.5mg tirz every 5days and 2mg also every 5 days, will be cutting back on tirz soon and up reta.

 

[miss-sanne]

i switched only 3 weeks ago, but i'm going down in tirz at the same time, and up i reta. Foodnoise is a bitch on reta. Tirz is my go to drug, but there were intolerable side effect on high dose 10 mg. But i broke my stall, so weight is moving again, so i'm quite happy at the moment.

 

[miss-sanne]

i switched only 3 weeks ago, but i'm going down in tirz at the same time, and up i reta. Foodnoise is a bitch on reta. Tirz is my go to drug, but there were intolerable side effect on high dose 10 mg. But i broke my stall, so weight is moving again, so i'm quite happy at the moment.

Oh btw, i'm stacking some cag 0,25 mg, it's AMAZING for appetite.

 

[Big Rossatron]

I'm still gaining weight on Reta, I don't even feel like I'm eating that much and I'm hungry all the time. Seriously considering going back to tirz.

 

[Thistley]

Switched from 15mg Tirz ( after long plateau) to Reta 3 weeks ago. Net weight GAIN of 1lb from starting weight after three weeks on Reta. Moving up to 4mg this week.

 

[Big Rossatron]

I'm wondering if my reta is real? Everyone seems to like it except me.

I just placed an order for reta from a different supplier so well soon see.

Edit also some cag

 

[Hawkeye512]

I posted an log/update of sorts in this thread, admittedly I'm not at the max dose of Reta.

I saw a lot of people were switching and wondered if anyone went back, or if they'd preferred Reta and why?

I started on Wegovy and moved to Zepbound, and then when my insurance change the starting BMI from 30 to 32, so I no longer qualified,, I bought some Reta. I never felt nauseous on it, but I just felt strange. I felt odd on it. I don’t know if it was combinations of supplements I take or medication or what, but I just felt weird on it. I finally went back to Tirz, but that doesn’t seem to be working very well this time and I’m not quite sure why. I’m thinking about doing a midweek bump of Reta to see if that helps.

 

[miss-sanne]

I started on Wegovy and moved to Zepbound, and then when my insurance change the starting BMI from 30 to 32, so I no longer qualified,, I bought some Reta. I never felt nauseous on it, but I just felt strange. I felt odd on it. I don’t know if it was combinations of supplements I take or medication or what, but I just felt weird on it. I finally went back to Tirz, but that doesn’t seem to be working very well this time and I’m not quite sure why. I’m thinking about doing a midweek bump of Reta to see if that helps.

When you re-start usually you need higher doses to feel the effect. The brain remembers.
And you can go up quicker than if you were a newbie.
But it will most likely still work well, just on higher doses.

 

[Retazempic]

I prefer reta because i had annoying constipation on tirz. But reta seems to make me kinda cold and i have a bit of allodynia on my arms. I can eat more normal meals without getting sickeningly full and still losing weight steadily.

Literally me too, all of it

 

[ContainHer]

I think this is what is causing a lot of my problems, I have some water retention, a little lower back pain, some swollen ankles. Nothing really serious but enough that I want to do something about it.

Is there anything I can stack with Reta or is going back to Tirz the better of the two options? I didn't really struggle with any bad sides and I went up to the max dose, but it was getting crazy expensive.

was doing a bit of forum surfing (I love hearing everyone's experiences) and stumbled upon your post. I take RT and stack it with KPV daily. Additionally, I cycle on and off of GLOW and the TB/BPC/KPV combo instantly helps with inflammation. Might want to stick with KPV only though if tumors run in your family medical history creating angeogenisis concern.

 

[Kalius]

I posted an log/update of sorts in this thread, admittedly I'm not at the max dose of Reta.

I saw a lot of people were switching and wondered if anyone went back, or if they'd preferred Reta and why?

I am trying to give Reta some time. All that I have read says that it takes some time to move up and gain any kind of appetite suppression when you move from Tirz. I was at max dose Tirz, but recently a few months ago started TRT (I’m 48 and had really low test and bad symptoms, not doing cycles or anything, no judgement for those who are though).

Having read quite a bit on Reta I knew it was going to be a rough transition, but the health benefits and apparent synergy with my TRT was very appealing.

I have been stacking it with some sema to start out and honestly it has become a weird cycle of cosntipation at night and the opposition in the morning then normal during the day.

The appetite suppression even stacking the sema is very light, and I have another 40lbs to lose, but I also have started weight training for the first time in years, so that could also be a strong factor in the appetite suppression not being super effective. I’m okay stagnating on the weight loss for a little bit if I can trade fat for muscle and build a solid routine.

I decided to stop the sema for a couple weeks and just updose faster on the Reta if I can handle it, and if my eating gets too out of control during this, I have some cagri as backup.

We will see!! I enjoyed Tirz a lot more, but exploring with Reta and giving it some time seems worth it.

 

[Retazempic]

Yeah, the Reta takes more time to reach the appetite suppression, but I found its lower side-effect profile to be well worth the trade off.

I’m 48 and have been thinking of TRT, but haven’t checked out whether there’s a forum on that here yet. If not, we probably should make one, since I also hear many guys are stacking with Reta

Catch you on the next thread, man

 

[exploitedworkerbee]

Gained weight on the transition, but eventually reta did its thing and was effective while still being able to enjoy food more than on other meds. I'm on tirz right now because i have to go off and on a bunch in coming months and i wouldn't want to do that with reta with its longer ramp-up time, but will def be going back to it as soon at i dont have so many events that mean flipping the glp1 switch off and on.

 

[exploitedworkerbee]

I'm wondering if my reta is real? Everyone seems to like it except me.

I just placed an order for reta from a different supplier so well soon see.

Edit also some cag

did you give it several months? it takes time to work its magic.

 

[Big Rossatron]

did you give it several months? it takes time to work its magic.

I've been running reta since June, currently at 10mg a week.

I have gained around 12 kg in that time, weight still going up almost 1kg a week.

 

[exploitedworkerbee]

I've been running reta since June, currently at 10mg a week.

I have gained around 12 kg in that time, weight still going up almost 1kg a week.

Ouch. Perhaps reta isn’t for you. Get up to that top dose and see what it does, and if not maybe jump ship. I gained some weight switching, but not that much and it leveled off in like 2 months before heading downward.

 

[brentm]

Switched from 15mg Tirz ( after long plateau) to Reta 3 weeks ago. Net weight GAIN of 1lb from starting weight after three weeks on Reta. Moving up to 4mg this week.

I was on a high dose of Tirz as well.... higher than you. I was able to titrate pretty quickly on Reta to 12mg a week. I suspect because of the Tirz. Reta works well.... pounds seem to be melting off. with a slight rebound this week.

I say I titrated up quickly, but I am not recommending anything to you. Just a piece of info for the data bank.

 

[Thistley]

Thank you @brentm it helps. I’m really trying to stay hopeful for Reta, so it encourages me to hear it took the high doses ( close to 12) for things to get moving. I hope that will be me soon.

For what it’s worth, I’m sad that Reta hasn’t so far worked because I was hoping I could go low and slow and have a long term low dose steady solution with Reta. Stayed the same this week. I can’t seem to break this dang plateau! Heading up to 6mg on Friday.

I had wondered if the 5mg creatine I was taking was messing with it. So I stopped. I also take an insulin sensitiser called inositol. It was recommended to me by my endochronologist and helps me regulate my hormones. The only thing that’s ever worked. No one can give me an answer ( obviously) as to whether it could be working against me. I don’t mean the forum I mean doctors, professional researchers and pharmacists. Stopping that this week to see what happens!!

 

[BooneDonk]

Doing more of what doesn’t work, doesn’t work. My favorite part of choosing your own medicine!