Pre filling glp1 syringe

I do when I have a "reconstitution/ pharmacy day". As in I sterilize my environment and reconstitute and pull up 20+ syringes (single dose, insulin syringe). Its a a trade off but for the convenience of having them ready to go when needed and also when I'm in the sterile zone in my head I am very meticulous with the process. I've been doing that for 2yrs+. With that said, out of all the batches I did, one syringe wouldn't depress. The plunger wouldn't move. I don't know what happened with that. I just tossed it. No other issues. L*lly has been hit with "aseptic technique" multiple times so I trust myself more than them.
 
When I am using vials with more peotides than I can use in three months (my comfort level for leaving things refrigerated), I am filling extra pen cartridges and freezing them. When one cartridge runs out, I pull another one from the freezer into a pen in the fridge. The biggest challenge so far has been labeling cartridges. Labels interfere with pen clearance, so I have to use sharpies labels I can easily remove before inserting cartridge into pen. This is my approach to GLP1s, since they seem very durable to freezing and long term storage.
For Tesamorelin I prefer using it all asap without freezing.

I've prefilled and frozen luer lock syringes for botox - I can never use all 100 units in one day. With BAC saline I am not concerned with bacteria. I have sterile luer lock caps on and syringes are stored in zip loc bags. I wouldn't risk it with fixed needle slin pins. BA keeps bacteria from multiplying inside the solution, but there's nothing to keep the fixed needle sterile once it's been used.
Wait wait wait. You're reconstituting with Bac water, filling cartridges and freezing those? I thought freezing reconstituted glp-1s was a big no-no because it denatures the peptides?
 
Wait wait wait. You're reconstituting with Bac water, filling cartridges and freezing those? I thought freezing reconstituted glp-1s was a big no-no because it denatures the peptides?
Test server did some testing with Tirz. It survived the freezing just fine. Good enough for my comfort level.
 

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