Pre filling glp1 syringe

I do when I have a "reconstitution/ pharmacy day". As in I sterilize my environment and reconstitute and pull up 20+ syringes (single dose, insulin syringe). Its a a trade off but for the convenience of having them ready to go when needed and also when I'm in the sterile zone in my head I am very meticulous with the process. I've been doing that for 2yrs+. With that said, out of all the batches I did, one syringe wouldn't depress. The plunger wouldn't move. I don't know what happened with that. I just tossed it. No other issues. L*lly has been hit with "aseptic technique" multiple times so I trust myself more than them.
 
stickfigure said:
When I am using vials with more peotides than I can use in three months (my comfort level for leaving things refrigerated), I am filling extra pen cartridges and freezing them. When one cartridge runs out, I pull another one from the freezer into a pen in the fridge. The biggest challenge so far has been labeling cartridges. Labels interfere with pen clearance, so I have to use sharpies labels I can easily remove before inserting cartridge into pen. This is my approach to GLP1s, since they seem very durable to freezing and long term storage.
For Tesamorelin I prefer using it all asap without freezing.

I've prefilled and frozen luer lock syringes for botox - I can never use all 100 units in one day. With BAC saline I am not concerned with bacteria. I have sterile luer lock caps on and syringes are stored in zip loc bags. I wouldn't risk it with fixed needle slin pins. BA keeps bacteria from multiplying inside the solution, but there's nothing to keep the fixed needle sterile once it's been used.
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Wait wait wait. You're reconstituting with Bac water, filling cartridges and freezing those? I thought freezing reconstituted glp-1s was a big no-no because it denatures the peptides?
 
hotdog! said:
Wait wait wait. You're reconstituting with Bac water, filling cartridges and freezing those? I thought freezing reconstituted glp-1s was a big no-no because it denatures the peptides?
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Test server did some testing with Tirz. It survived the freezing just fine. Good enough for my comfort level.
 
scarywood75 said:
I'm not trusting anything in life that have a chance to kill me
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I do it all the time. How would it kill you? Can you provide a source for this information? You are very unlikely to die from a subcutaneous injection. I understand everyone has a risk tolerance level and I definitely support your decision to not do it.
 
Griffwisha said:
I do it all the time. How would it kill you? Can you provide a source for this information? You are very unlikely to die from a subcutaneous injection. I understand everyone has a risk tolerance level and I definitely support your decision to not do it.
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I mean of course it's unlikely, and I don't have to provide a source for that, you think USP guidelines are just some joke?

I haven't made the standards, but people with big brains did. If it was fine to do, then we would not have them?

Ask any medical person if they are allowed to do that and they'll tell you they can't. Unless they follow USP Chapter 797 guidelines.

Now, if you think it's absurd and all, fine, but remember that standards and strict guidelines are there for a reason. I chose to follow the guidelines the best I can, because I'm no smarter than the people that made them.
 
just in case we don't all maintain clean room standards, i suggest we keep a few antibiotic pills in case the injection site starts becoming visibly infected. get ahead of it. considering we will be doing this for many years it bound to happen eventually.
 
Griffwisha said:
I do it all the time. How would it kill you? Can you provide a source for this information? You are very unlikely to die from a subcutaneous injection. I understand everyone has a risk tolerance level and I definitely support your decision to not do it.
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I basically agree. I don't pre-fill my needles because weighing the risk of pre-filling versus the benefit of pre-filling (which is none as far as I can tell), my scale weighs in favor of filling right before I inject. I'll defer to anyone with a scientific/medical background who disagrees with me, or any who appears like they understand scientific/medical stuff.
 
raw_oyster_eater said:
just in case we don't all maintain clean room standards, i suggest we keep a few antibiotic pills in case the injection site starts becoming visibly infected. get ahead of it. considering we will be doing this for many years it bound to happen eventually.
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I have no leftover antibiotic pills. I take them according to their instructions, which is to take all of them. Would taking a few pills help solve the problem? Or would it help the infection that I got develop antibiotic resistance so that by the time I go to the vet, my infection is harder to treat? I don't know.
 
scarywood75 said:
Are you turning this into a competition? I'm just commenting on a GLP1 forum, I'm not an insta babe lol
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ScarJo, you'll always be hotter than an insta babe.

keangkong said:
To catch up with chmuse, you’ll have to abandon your relentless insistence on posting only high quality stuff.
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Wait
 
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