GLP-1 Forum

Reconstitution advice

MisterGeorge

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Been researching for a couple of months now and finally jumped and ordered 10mg Reta kit from Jeep yesterday. Ahead of it arriving I’ve ordered BAC water and 1ml needles. The calculators say that at a 1mg dose I will get 10 doses per vial. Will it last that long in the fridge once constituted? My research is saying it will only last a month and others say three months. From your experience can anyone give me any advice?
 
Your 10mg doesn't have 10mg in it, it has more (overfill). Also, you'd titrate up after 4 weeks, so those 10 doses will go down. Look up the COA for that R10 and see exactly how much is in there. Use https://btpepcalc.com/ to calculate your required dose. How long the vial lasts is how comfortable you are about using it past 4 weeks.
 
Your 10mg doesn't have 10mg in it, it has more (overfill). Also, you'd titrate up after 4 weeks, so those 10 doses will go down. Look up the COA for that R10 and see exactly how much is in there. Use https://btpepcalc.com/ to calculate your required dose. How long the vial lasts is how comfortable you are about using it past 4 weeks.
Thanks so much for this. COA? I thought I had done all my research and still there’s lots to learn? I thought I’d follow and slow rather than titrate up beyond 1mg. We’ll see I guess
 
No, you don't have to. Clinical trials had them titrate up after 4 weeks.

@MisterGeorge A COA is a test done by a lab to determine how much is in the vial and how pure it is to a reference sample. Most vendors overfill their vials, so your 10mg might end up being close to 15. It's impossible to know exactly how much is in your specific vials, so you go based on COAs and average out from there.

Vendors will send their sample to a lab for testing and will get a report back. They usually send 3 vials. But vendors tend to either lie about the results (fake the COA) or have very old tests. Which is where 3rd party testing comes in. That's where someone like you or me sends a vial or more to a lab and gets the COA themselves and share with the community.
 
Thanks so much for this. COA? I thought I had done all my research and still there’s lots to learn? I thought I’d follow and slow rather than titrate up beyond 1mg. We’ll see I guess

There is no COA for the R10 yet but both vendor and my group are currently shipping vials in to Janoshik so expect COAs to be ready next month.

My partner and I have been using JEEP R10 the past 3 weeks, both lost 3~5kg now.
 
Been researching for a couple of months now and finally jumped and ordered 10mg Reta kit from Jeep yesterday. Ahead of it arriving I’ve ordered BAC water and 1ml needles. The calculators say that at a 1mg dose I will get 10 doses per vial. Will it last that long in the fridge once constituted? My research is saying it will only last a month and others say three months. From your experience can anyone give me any advice?
Up the dose and exercise everyday for the best results
 
Been researching for a couple of months now and finally jumped and ordered 10mg Reta kit from Jeep yesterday. Ahead of it arriving I’ve ordered BAC water and 1ml needles. The calculators say that at a 1mg dose I will get 10 doses per vial. Will it last that long in the fridge once constituted? My research is saying it will only last a month and others say three months. From your experience can anyone give me any advice?
The general guidance is that a vial should be tossed out after 30 days. However, this is based on things like vials are mostly used in hospital settings and they may have pinned from that vial fifty times in a month. People who use vials at home, such as insulin, may pull from the vial multiple times a day. With the GLP medication, you are usually only pulling from the vial once a week, so you are far less likely to introduce a contaminant into the vial.

I usually go 6 weeks on a vial and then will toss it. I'm a diabetic though, and I am 55 years old with an autoimmune disease, so I am take a lot of precautions, maybe more than the average person. I have seen others post that they have gone months on the same vial and not had any problems.

I think that what is important is that you decide what your own risk tolerance is and not necessarily base it on what a bunch of randos like me say🙂 Thirty days is the general guidance. For me, 45 days is as much risk as I want to take, and although it's a little painful to throw out what is probably still good medicine, I remind myself how cheap these vials actually are.
 
Also, let me save you some confusion later down the line; as soon as I buy something, I download the COA into a folder where I have my COA's. My naming convention is

batchnumber, whether it's a vendor or volunteer test, vendor, what it is, month and year I bought it, top color, and color of the thermos where I'll be keeping it in the fridge.

so this:

G2025086380vendor_GYC_KLOW80_9-25_pinktops_greenthermo

is what a batch of Klow from GYC I bought in September with pink tops looks like, and it's in a green thermos.

When it gets here, I load it into the thermos and print out all the COA's I have for it and put THAT in the thermos. (stole that part from @chmuse ) Then I label it with what's in it and I'm good. That way, when I go to recon, I've got a clear record of what it is, where it is, and how many mg I should expect are in the vial. I've ALSO got a record of which batches I have, so that if someone gets a test in where "one of GYC's t-30's tested questionable," I can see at a glance in my COA's folder if I've been impacted.
 
why store it in a thermos in the freezer?
Individual preference. A lot of what I buy is intended for long-term storage, because it's glp-'1s or things I expect to use a long time and want to protect against unavailability, so I pack three kits into a 13.5 oz food-container thermos, and pack in some silica packets at the top. The thermos is airtight and protects against any temperature swings and with the silica packets, the humidity is pretty controlled. It also makes it very easy to pull what I want without things shuffling around in the freezer; I know if I want klow, I'm looking for a green one, and both the side and the top are labelled so I can spot it quickly. And the thermoses are very compact and easy to pack together, so my space is controlled. Some of them won't be opened for years.
 
That seems overkill. 😅
It's pretty common. I store in a thermos with silica gel packets. I do this because because I don't have a generator on my freezer, but the thermos will give me many extra hours of frozen stability. I also live in fire country and sometimes have to vacate my property for weeks at a time in the summer, and generally the electricity is cut when there are active fires around. Having it packed into a thermos already saves time in an emergency and protects it from an unnecessary thaw as I transport to new freezer.

I'm well aware that I am taking lightly tested unregulated medications that are still in trial and are not hermetically sealed or made in sterile laboratories, so I am cautious where and when I can be.

If you want to throw your vials on your dashboard and drive around in 110 degree weather and reuse needles that you found in a Walmart parking lot, go for it🙂
 
If you want to throw your vials on your dashboard and drive around in 110 degree weather and reuse needles that you found in a Walmart parking lot, go for it🙂
Seconded. I mean, I don't really care what else anybody else does about storage. The point isn't the storage system, but keeping documentation in a way that makes your life easier. I think fondly of past-me every time I go to pull a vial of something from my way-too-much system, and it's super easy to be like "oh, the survo's in a pink one," then I pull the pink one and the labelling right on it is like "hey, this 12 is actually 16" and I can reconsitute accordingly without having to remember a bunch of different things.
 
Molly from JEEP is great. I've used them and had no issues. Also, Google peptide calculator. You can play around with inputs to see how much you're dosing, how many shots per vial, etc.
Once reconstituted you are way more likely to pin it all before it goes bad. Just maintain sterilization with alcohol wipes and observe that your vial isn't cloudy, you good to go!
 
Individual preference. A lot of what I buy is intended for long-term storage, because it's glp-'1s or things I expect to use a long time and want to protect against unavailability, so I pack three kits into a 13.5 oz food-container thermos, and pack in some silica packets at the top. The thermos is airtight and protects against any temperature swings and with the silica packets, the humidity is pretty controlled. It also makes it very easy to pull what I want without things shuffling around in the freezer; I know if I want klow, I'm looking for a green one, and both the side and the top are labelled so I can spot it quickly. And the thermoses are very compact and easy to pack together, so my space is controlled. Some of them won't be opened for years.
Mind linking to the coolers you use? I like this idea. Also offer some protection against power failure
 
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