GLP-1 Forum

Reta with Sema

I’m in month 4 of a Reta/Sema stack. The goal was to completely switch over to Reta but I like the appetite suppression I get from Sema. I’m on week 6 of 6mg Reta and three days later 1mg of Sema. The last 4 weeks it’s been a steady 1-1.5lb a week loss. The worst side effect so far has been allodynia which is no worse or no better than it was with Sema alone.
 
Has anyone used both at the same time? Used Sema for the higher GLP 1 affinity, Reta for everything else? If so what was your dose? Thanks
I take 1mg of sema on Sunday followed by 2mg of reta on Wednesday.
I started sema on May 4th. I took an extra month at .5mg but otherwise followed the standard wegovy titration schedule. I started reta on August 6th and gradually upped the dose until I got to 2mg on September 2th. I plan to sit at these doses for awhile.

I have lost about 35 pounds at this point and my only side effect has been some discomfort during bowel movements. Nothing that isn't manageable.
 

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