Retatrutide 1 mg/week – When Did It Start Working for you?

[dandam]

I’m currently on retatrutide 1 mg per week, split into 0.5 mg twice weekly.

For those using the same or similar dosing:

After how long did you start noticing appetite suppression?
When did weight loss become evident?
What side effects did you experience, if any?

Sharing timelines and concrete experiences would be very helpful.

 

[CNCCurrency]

Not until around 4mg

 

[HumanusExMachina]

Appetite suppression started working for me about 3 days in at 1mg once weekly. I had weight loss in the second week. As far as side-effects, I had brief bouts of fatigue over the first 2-3 weeks, along with some stomach discomfort that wasn't quite up to nausea.

 

[yrrdead]

I started about the same dosing as you(hard to know exactly with smaller vials and overfill) but lets assume similar dosing. Though I am dosing every 3 days.

1. Probably after my second pin. Though hard to know what is drug vs placebo.

2. Well I was tracking calories from my first pin and trying to weigh myself at the same time every day. So the weight loss was almost immediate due to water/inflammation + calorie deficit. I will say that is pretty normal with any calorie restriction in my experience.

3. Burping (no sulphur), constipation (calorie restriction doesn't help), little indigestion w/ fatty meals. Some dehydration headaches.

 

[Indiana]

It took 3 days before the food noise stopped. One thing I don't like about it is the skin sensitivity. But I love how my body looks now.

 

[randombetrayal]

I’m currently on retatrutide 1 mg per week, split into 0.5 mg twice weekly.

For those using the same or similar dosing:

After how long did you start noticing appetite suppression?
When did weight loss become evident?
What side effects did you experience, if any?

Sharing timelines and concrete experiences would be very helpful.

I am on this same dosing for maintenance and general body recomp efforts, 0.5 mg every 3 days. I found that about 4-6 weeks was when I felt the appetite control. I initially lost about 12 pounds earlier this spring and have maintained it since that point, as it was my goal weight. As mentioned, I am now in maintenance and attempting to recomp approximately 5 pounds of fat into muscle and tap into the insulin-resistant benefits Reta provides. If I increase the dose, I find it too hard to keep hitting my macros to actually add muscle. Plus, with the amount of protein needed coupled with a larger dose, I am not sure the bowel movement issue would be too good of a situation, at least for me.

 

[Fait88]

First time user of peptides here. I pinned myself 1mg reta last Jan 3rd and I noticed the following day I was ignoring the foods in the kitchen which I normally “taste and take a bite” and eventually eat the whole plate later on.

No nausea or any side efffects. I started calorie deficit on Dec 29, so i can’t tell the weightloss was from reta alone because prior pinning myself, i was in a deficit already. Lots of water weightloss tho.

 

[Gohengrin]

I noticed it with 4mg. 6mg Was better. I did 2mg 4 weeks, then 4mg 4 weeks and so on. The last 4mg shot was noticable.
I also had no side effects until then. Now I get red itchy spots at injection site, because of the reta itself.

 

[woundcarping]

…Plus, with the amount of protein needed coupled with a larger dose, I am not sure the bowel movement issue would be too good of a situation, at least for me.

Are you monitoring/achieving fiber and water intake?

 

[cowboy54]

started on 0.5mg weekly and found that within a day the food noise disappeared, however I could generally eat 3 meals a day but wasnt overeating.
Weight I had lost 6 pounds in the first 2 weeks, I know a good percentage was probably water loss
Side effects I only noticed more fatigue when running, I am training for a marathon so over 10 miles was finding harder. Ive since tried 0.5mg every 2 weeks, and am now cutting out reta until I complete the race as just cant do both.
Start of March I will go back to 0.5 or 1mg for a few months as long distances will scale down