raw_oyster_eater
Senior Member
i'm teaching her how to low rent post.
so what's your general sourcing strategy now?
- Thread starter clayd
- Start date
chmuse
Public Nuisance
But I already made friends with the boys who talk nerdy to me!
Windingroads06
Less is More
I despise lazy.
chmuse
Public Nuisance
Unfortunately, I like him.
And for the sake of his liver, I'll spoon-feed him if it gets him drinking less. He just had a baby, he's not allowed to kill his organs anymore.Windingroads06
Less is More
I get it. I have a few friends like that.Unfortunately, I like him.
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Then beefsteak or rawoystereater becomes moderator.
chmuse
Public Nuisance
But zippity's the one who can grant mod powers.
Can you imagine what this place would look like without @exploitedworkerbee here?
How the hell did you get posting privileges already???
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Without a decent moderator, I'd be gone. Complete free speech on a forum sounds great, in theory. Having a person who moderates too much makes the forum no fun.But zippity's the one who can grant mod powers.
Can you imagine what this place would look like without @exploitedworkerbee here?
chmuse
Public Nuisance
I don't know, but no one seems to hate me yet, so, win? One day of reading articles Ghoul's posted and I'm reconsidering my entire approach to sema.How the hell did you get posting privileges already???
Yeah, I prefer a place somewhere between reddit and whatever the latest iteration of 4chan is.
I have been a lurker on Meso for years.. but I don't have posting privileges on that thread for some reason...
Tell me about the Sema.
chmuse
Public Nuisance
I have no clue, even a mod stepped in and said I wasn't in trouble for posting there. Tracy might ban me when/if s/he gets back. I'm going to have to order from a different email.
Well, I'm already sold on the filtering and increased dosage size to prevent giving myself an immune response. I've never done a .5 ml shot before, but the logic tracks, as does filtering to avoid anything extra in there that will trigger your bodies immune system. I'd never considered before that UGL vials themselves could be an issue- I'm actually a lot more sold on using the pens now, especially if I filter the peps into them. I bought them mostly because of fomo, and I hate having to leave the pen in for like, ten seconds without it dribbling, but it sounds like the benefits are worth it.
I'm not quite sold on doing a seven day cycle, but that's because I'm using sema for something a little more serious than turning off food noise- and those two days where I have noise again are where I tend to fail.
I somehow hadn't realized the GIP receptor was the one that seems to work best for targeting liver damage and healing. My focus had mostly been on turning off cravings, which is why I gravitated towards sema even though tirz is better for weight loss and side effects- I WANT some of the side effects. So I have to rethink my approach; I want my liver to heal, but tirz also doesn't work as well for noise. My original plan was to stick to sema as long as possible, then move on to tirz, stacking with sema if necessary; I'm putting a little more thought into whether stacking is really the best solution.
I do wonder if I need to try a little harder to get past the tutorial stage of the forum that shall not be named, since I'm under the impression there's a more scientific approach taken there. I don't listen well to 'trust me bro' or 'you're being dumb' but when you back it up with actual studies....
Why even think about stacking when your dosage is still so low? My suggestion would be to increase your dosage first before you consider anything else. You are still SO low.I have no clue, even a mod stepped in and said I wasn't in trouble for posting there. Tracy might ban me when/if s/he gets back. I'm going to have to order from a different email.
Well, I'm already sold on the filtering and increased dosage size to prevent giving myself an immune response. I've never done a .5 ml shot before, but the logic tracks, as does filtering to avoid anything extra in there that will trigger your bodies immune system. I'd never considered before that UGL vials themselves could be an issue- I'm actually a lot more sold on using the pens now, especially if I filter the peps into them. I bought them mostly because of fomo, and I hate having to leave the pen in for like, ten seconds without it dribbling, but it sounds like the benefits are worth it.
I'm not quite sold on doing a seven day cycle, but that's because I'm using sema for something a little more serious than turning off food noise- and those two days where I have noise again are where I tend to fail.
I somehow hadn't realized the GIP receptor was the one that seems to work best for targeting liver damage and healing. My focus had mostly been on turning off cravings, which is why I gravitated towards sema even though tirz is better for weight loss and side effects- I WANT some of the side effects. So I have to rethink my approach; I want my liver to heal, but tirz also doesn't work as well for noise. My original plan was to stick to sema as long as possible, then move on to tirz, stacking with sema if necessary; I'm putting a little more thought into whether stacking is really the best solution.
I do wonder if I need to try a little harder to get past the tutorial stage of the forum that shall not be named, since I'm under the impression there's a more scientific approach taken there. I don't listen well to 'trust me bro' or 'you're being dumb' but when you back it up with actual studies....
chmuse
Public Nuisance
Oh, that's definitely the plan. I plan to go as high on sema as possible before upgrading. I only added the cagri because the cagrisema is on par with tirz and the studies showed it's great for fatty liver. I'm talking long term. Ideally I won't touch the tirz until/unless I stall out on 2.4sema.
penewbie
Registered
I'm so lucky I can't post on Meso, I'd be non-stop arguing with those guys all day long.I have no clue, even a mod stepped in and said I wasn't in trouble for posting there. Tracy might ban me when/if s/he gets back. I'm going to have to order from a different email.
Well, I'm already sold on the filtering and increased dosage size to prevent giving myself an immune response. I've never done a .5 ml shot before, but the logic tracks, as does filtering to avoid anything extra in there that will trigger your bodies immune system. I'd never considered before that UGL vials themselves could be an issue- I'm actually a lot more sold on using the pens now, especially if I filter the peps into them. I bought them mostly because of fomo, and I hate having to leave the pen in for like, ten seconds without it dribbling, but it sounds like the benefits are worth it.
I'm not quite sold on doing a seven day cycle, but that's because I'm using sema for something a little more serious than turning off food noise- and those two days where I have noise again are where I tend to fail.
I somehow hadn't realized the GIP receptor was the one that seems to work best for targeting liver damage and healing. My focus had mostly been on turning off cravings, which is why I gravitated towards sema even though tirz is better for weight loss and side effects- I WANT some of the side effects. So I have to rethink my approach; I want my liver to heal, but tirz also doesn't work as well for noise. My original plan was to stick to sema as long as possible, then move on to tirz, stacking with sema if necessary; I'm putting a little more thought into whether stacking is really the best solution.
I do wonder if I need to try a little harder to get past the tutorial stage of the forum that shall not be named, since I'm under the impression there's a more scientific approach taken there. I don't listen well to 'trust me bro' or 'you're being dumb' but when you back it up with actual studies....
There is zero merit to the idea that higher volume would decrease immune response. That entire volume is fully absorbed in under a minute anyway.
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I go back and forth on how much I believe what Ghoul is saying. My interpretation is that he's a fairly smart individual that has read a whole bunch of articles and papers and is now very firmly convinced he understands them very well and is an expert on them.
Which, well, I've read a lot of articles and papers and think I understand them decently well, to the point where I modify my behavior and share my opinions on them... but I also make sure to indicate that I'm a layperson presenting my best effort interpretation on what I believe after reading things and why I believe it.
His very matter-of-fact attitude about just how right he is on every. single. subject. makes me a bit uncomfortable.
Which, well, I've read a lot of articles and papers and think I understand them decently well, to the point where I modify my behavior and share my opinions on them... but I also make sure to indicate that I'm a layperson presenting my best effort interpretation on what I believe after reading things and why I believe it.
His very matter-of-fact attitude about just how right he is on every. single. subject. makes me a bit uncomfortable.
My understanding is all of the immunogenicity stuff is based off of what we've seen in some animal studies specifically with hgh, e.g. https://pubmed.ncbi.nlm.nih.gov/19569057/
I don't know that there is anything resembling settled science around it for humans with hgh, much less other peptides and proteins.
chmuse
Public Nuisance
I have a ton of articles open to explore later. I'm not exactly a genius so I have to do more reading to come to my own conclusion, but it makes sense to me that more concentrated = more clumping = stronger immune reaction. I keep my doses small because I'm a weenie and big shots are scary, but if the science backs it up I'll listen.
I'm not there to argue, I'm there to learn. I'm pleasantly surprised by the level of research these guys are doing, my ex who used AAS was definitely dumb as a brick and that colored my impression going in.
There's a reason I have that I'm stupid in my signature. I can accidentally sound like I know what I'm doing. I don't.
The amount of care that pharma puts into avoiding immunogenicity makes me feel like maybe it's more of a concern than I'd given thought to. He's posted a ton of stuff on it and it requires more reading for me to decide if it makes sense to actually be concerned. That being said I don't see any problem with being more stringent with safety stuff other than it's annoying and I'm lazy. It's not like I'm paying out the ass for any of my supplies.
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penewbie
Registered
Sure, intuitively it makes sense. Yet EL is doing tirz at 30mg/ml, and is moving on to 50mg/ml for their increased dosage trials. Meanwhile NN is doing sema at 3.2mg/ml, and presumably testing out 3x that for their own increase dosage trials.
So, the increased concentrations doesn't seem to concern them as much as it does ghoul.
chmuse
Public Nuisance
Yeah, that's fair. Like I said, I have to look into it. My doses are 5x smaller than he's suggesting, right now my .375mg dose of sema is 15u. I'm going to have to do the math. He's also made some points about how your body will absorb it at a different rate, and that your body will absorb it faster if it's in a smaller dose of liquid. I'm thinking along the lines of how you don't crush ER pills, because the absorption rate is part of how it works.
I'm not trying to make any claims either way. I'm just saying I've got more rabbit holes to go down.
Edit: absorption not abortion. Oops.
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