Switching from sema to tiirz

brittmiche

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Does it seem like people who start on sema that switch to tirz have no luck with it to yall? I don't know of anyone who started on sema, lost weight, maxxed out, switched to tirz that has had any luck.
 
Does it seem like people who start on sema that switch to tirz have no luck with it to yall? I don't know of anyone who started on sema, lost weight, maxxed out, switched to tirz that has had any luck.
I've heard of some. I frequently hear, thought, about folks who maxed out on semaglutide at 2.4, then start at 2.5 or 5 mg of tirzepatide and then complain about not losing any more weight while they're on the 2.5 or 5 mg of tirzepatide. Or I hear about people who started at 7.5 mg of tirzepatide or higher and have bad side effects. I believe the key is patience. The tirzepatide will likely cause greater weight loss. But it will take a while. The semaglutide user will probably have to get to 10 mg or higher to see much loss.
 
Does it seem like people who start on sema that switch to tirz have no luck with it to yall? I don't know of anyone who started on sema, lost weight, maxxed out, switched to tirz that has had any luck.
 
I've heard of some. I frequently hear, thought, about folks who maxed out on semaglutide at 2.4, then start at 2.5 or 5 mg of tirzepatide and then complain about not losing any more weight while they're on the 2.5 or 5 mg of tirzepatide. Or I hear about people who started at 7.5 mg of tirzepatide or higher and have bad side effects. I believe the key is patience. The tirzepatide will likely cause greater weight loss. But it will take a while. The semaglutide user will probably have to get to 10 mg or higher to see much loss.
This is currently my exact situation. I stalled on Sema at the end of January. Due to life circumstances, I actually decided to slowly switch...I tapered down a bit and then made the switch to T. I tapered up (on my own schedule) from 5 and as of this week, I am on 10 every 5 days - 2 lbs down this morning for the first time since January! 💃
 
This is currently my exact situation. I stalled on Sema at the end of January. Due to life circumstances, I actually decided to slowly switch...I tapered down a bit and then made the switch to T. I tapered up (on my own schedule) from 5 and as of this week, I am on 10 every 5 days - 2 lbs down this morning for the first time since January! 💃
Stick with it! 👍
 
This is currently my exact situation. I stalled on Sema at the end of January. Due to life circumstances, I actually decided to slowly switch...I tapered down a bit and then made the switch to T. I tapered up (on my own schedule) from 5 and as of this week, I am on 10 every 5 days - 2 lbs down this morning for the first time since January! 💃
Did you notice any differences as you switched? Exhaustion? Food noise? Nausea?
 
Did you notice any differences as you switched? Exhaustion? Food noise? Nausea?

Trying to stay neutral with this, but...Exhaustion? More every day. Food noise? Definitely an issue I wasn't prepared for. I'm using the Shotsy app to track my Tirz levels so that I can fine tune dosage as I go. I upped my dose yesterday to 12.5 but dropped back to every 6 days - the chart looks more solid here, so just 🙏🏻 reality reflects this as well.

Feeling a bit defeated today if I'm honest. Everyone loves their Tirz so much, so I'm sticking this out (as advised! 😆) but man - I just really feel like I had much more control on Sema?

As for nausea, no real issues with other side effects on either of the two. I would have random things pop up along the way on Sema (heartburn for a day or two after injection, Allodynia for a few weeks...) but they subsided quickly and went away to never return.
 
From what I remember hearing (on a Youtubed podcast), Dr. Seeds says that fatigue from peptides is your body healing (which sounds more like BS everyday but puts a positive spin on it).

Some info/advice from a future overlord (Google Gemini):

Google Gemini said:
While fatigue is not listed as a common side effect of tirzepatide by the manufacturer, some individuals have reported experiencing it. Here's why tirzepatide might cause fatigue:
  • Reduced Calorie Intake: Tirzepatide can significantly decrease appetite, leading to lower calorie consumption. This reduced energy intake can result in feelings of tiredness.

  • Gastrointestinal Issues: Common side effects like nausea, vomiting, and diarrhea can lead to dehydration and electrolyte imbalances, both of which can cause fatigue.

  • Blood Sugar Fluctuations: Although tirzepatide helps manage blood sugar, some individuals might experience fluctuations, particularly low blood sugar (hypoglycemia), which can cause fatigue, dizziness, and confusion.

  • Body Adjustment: When starting tirzepatide, your body needs time to adjust to the medication. This initial adaptation period can sometimes manifest as increased tiredness.

  • Impact on Sleep-Wake Cycle: Tirzepatide may affect the hypothalamus, a part of the brain that regulates sleep and wakefulness, potentially leading to fatigue, especially during the initial stages of treatment.
Here are some strategies to help manage fatigue while taking tirzepatide:
  • Stay Hydrated: Drink plenty of water throughout the day to prevent dehydration. If you experience nausea or vomiting, consider electrolyte solutions.

  • Eat a Balanced Diet: Focus on nutrient-rich foods and eat smaller, more frequent meals to maintain stable energy levels. Avoid skipping meals.

  • Get Regular Exercise: Moderate physical activity can help boost energy levels and reduce fatigue.

  • Establish a Regular Sleep Schedule: Maintain a consistent sleep routine to regulate your body's sleep-wake cycle.

  • Monitor Blood Sugar Levels: If you have diabetes, regularly check your blood sugar to identify and manage fluctuations.

  • Communicate with Your Healthcare Provider: If fatigue is persistent or interferes with your daily activities, discuss it with your doctor. They can help identify the cause and recommend appropriate management strategies or adjust your treatment plan if necessary.
 

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