The itchies and the scratchies...

[cldfront]

So I've had a spot between my shoulder blades (exactly where you can't reach, although now that I'm thinner I can reach better), lower back, my c-section scar, and kind of upper hip area that have been itchy for many moons. If I don't regulate myself, I can bleed about it. Recently I've developed an additional intense itch on my outer arms, and collarbone area. In the past couple of days it's been enough to disrupt my sleep, which is my line for tolerating sides.

My current stack is 15mg Tirz (1.5 years on Tirz now) and 2.4mg Survo - both on a weekly cycle (Wed Tirz/Sun Survo). Today is shot day for Survo and I think I'm going to skip it and just see if I can back down the itch to tolerable levels with the Tirz alone.

Anyone else have similar trouble and can speak to solutions? I added the Survo because I was stalled with Tirz alone and I would like to drop another 20 in a perfect world. I might move to Cagri if dropping the Survo helps with the itch. Thanks for any thoughts!

 

[Good-Heart6425]

Prednisone prescription will do wonders. Also cirtirizine OTC antihistamine tabs. Avoid Scratching: Keep nails short to prevent injury.

 

[cldfront]

Prednisone prescription will do wonders. Also cirtirizine OTC antihistamine tabs. Avoid Scratching: Keep nails short to prevent injury.

For some reason I'm really reluctant to medicate my medication. I might try an otc med though, so thanks for the suggestion!

 

[anhydrous]

For some reason I'm really reluctant to medicate my medication. I might try an otc med though, so thanks for the suggestion!

Totally agree at least on prednisone. I might start with a topical antihistamine like benadryl cream.

 

[funlog]

On Reta and was itchy in the same place as well as the ankles. Switched from hot showers to cool ones and it stopped. Good luck, I know it can drive you crazy.

 

[lessthanhalf]

Localised injection site reactions are common. Generalised drug allergy type reactions are also not rare- a few percent. Much rarer and more obscure and possibly serious adverse skin reactions have been reported. Fixed drug eruptions , where a reaction to a particular drug causes an effect in the skin at a particular site, is a thing that happens, I have not come across it happening for tirzepatide, and survodutide is too new to have widespread use required to generate the sort of info required to even tell, so if it did not happen in the trials then nobody probably knows.
Just so this makes some sense I had a weird rash a year ago and one of the possible causes was a drug rash and semaglutide was one of the possible culprits , so I did a ridiculous amount of research on GLP drug reactions.
I also copied this into a very highly science based prompted version of chatgpt .
I would suggest getting a medical or better still a dermatologist opinion, maybe try ceasing survo first, but if it does not go away soon, it would be definitely time to get it checked out. Unfortunately trying to diagnose not obvious skin reactions that might or might not be a drug reaction is hard, even for specialists, and no one is going to know anything much about survo.
( I never got a definite diagnosis after 3 biopsies, blood tests and a couple of dermatologists, and a ton of research myself , and I still have it )
And it may not be related to the drugs. This is the summary of what chatgpt thought about your post copy/pasted into it with a couple of questions from me.
Please note this is not medical advice as such, just a suggestion that maybe you need to get it looked at.
Most plausible possibilities (roughly ranked):
Drug-induced generalized pruritus with scar-localized flares
Koebner-type inflammatory dermatosis triggered by systemic immune change
Neuropathic itch plus unrelated systemic itch
Less likely: fixed drug eruption.
The fact that tirzepatide was tolerated for 1.5 years makes survodutide the more suspicious agent.
✅ Bottom line:
The symptoms sound more like drug-related pruritus or inflammatory skin reaction than a classic fixed drug eruption, though scar-localized inflammation can occur in some immune skin conditions.

 

[lessthanhalf]

It might be a good idea to get it looked at by a doctor or at least take some photos before trying to treat it symptomatically with antihistamines or steroid creams, in case it helps and makes it harder to work out the cause.

 

[Jerrydee]

While I started on reta , about after 2 weeks got bad itch in foot and right ankle , but I started ignoring it , I never scratched and endured , post 4 weeks it was gone , what my assumption is , it’s because reta is adjusting in your body these are temporary I guess

 

[cldfront]

It might be a good idea to get it looked at by a doctor or at least take some photos before trying to treat it symptomatically with antihistamines or steroid creams, in case it helps and makes it harder to work out the cause.

Thanks for all that info - there's actually nothing to see unless I create damage myself from scratching the itch. My skin looks totally normal otherwise. No site reaction from injection or anything like that - just an enduring itch that comes and goes. I'm just going to 86 the Survo and see how we roll. I appreciate the input!

 

[Omxxl]

Hahaha, I thought it was just me being picky, but my back has been itching a lot since I started with Reta, and my wrists and elbows too.

 

[RetCurious]

I'd try to symptomatically treat it to see if it responds before screwing w/ a doctor.
Usually a little hydrocortisone cream and follow up with a good moisturizer works for me.
I also take benadryl daily during allergy season but that causes drowsiness for some so a cream is a good substitution.