This was just posted by a vendor a few minutes ago and I wanted to get everyone's thoughts on this.
Nonsense?
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Not really bull - depends on which peptide we are talking about
If it's frozen right after production and kept frozen, keeping it frozen is always the best option.
However, if it has been thawed - re-freezing might not be the best choice. The expected potency loss of semaglutide stored at 36-46°F is under 2% in 24months for example.
While re-freezing a thawed product could potentially cause issues with structural integrity, moisture, affecting the cake so it's difficult to reconstitute, and it could break the integrity of the vial.
So all in all, I wouldn't say it's bad advice.
But the way it's phrased bothers me, since it could be a buildup to saying that if there is an issue with the product, it's because you stored it incorrectly.
For peptides like sema, tirz and reta - they are quite stable and you almost have to try in order to significantly damage them.
So while storage conditions are important and can affect purity and potency - The manufacturing quality is equally if not more important, since that is an important factor in how stable your lyophilized product is and how easy/difficult it is to damage it.