What are the best peptides for knee injury?

Omxxl

Omxxl

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I've had surgery on both knees for meniscus and cruciate ligament tears, in addition to joint degeneration due to cartilage wear. I've been recommended a therapy where they draw blood and inject something like Matrix cells or something similar. They also mentioned peptides like BPC and TB500. I don't know if any of you have tried it and if it has been helpful for this type of cartilage wear injury.
I would greatly appreciate your opinions and experiences, friends.
 
BPC-157, TB-500, GHK-Cu, Cartalax. Dont buy blends. Inject BPPC near injury site, and TB-500 systemically. I use BPC and TB for my torn rotator cuff and biceps tendinosis. Also, consume 30 grams of collagen peptides daily with hyaluronic acid, vitamin C, and glucosamine and chondroitin.
 
Omxxl said:
I've had surgery on both knees for meniscus and cruciate ligament tears, in addition to joint degeneration due to cartilage wear. I've been recommended a therapy where they draw blood and inject something like Matrix cells or something similar. They also mentioned peptides like BPC and TB500. I don't know if any of you have tried it and if it has been helpful for this type of cartilage wear injury.
I would greatly appreciate your opinions and experiences, friends.
Click to expand...
I have used KLOW and have noticed a significant reduction in pain. My back pain is gone and my knee pain is now tolerable. I was told that I basically had no cartilage left when I saw an orthopedic doctor about it .. so expecting no pain at all would be asking a bit much.

KLOW is a mix of BPC-157, TB-500, GHK-Cu, and KPV.

It comes in 80mg vials. I mixed it with 3mL of BAC and take 10 units a day. You do not need to inject into the injured area. One vial lasts me 30 days. I then take a break for 2 weeks or so and then mix a new vial. I don't know the full details of why I need to take that 2 week break but it is an established protocol.
--> click here to learn more about KLOW <--

Cartalax is also something worth looking into. I haven't tried it personally but its on my radar and I have been looking for a source. Sadly my favorite vender doesn't carry it and my second favorite vender doesn't have a COA listed for this product even though most of their other products do have a COA and that worries me.

--> click here to learn more about Cartalax <--
This website has capsules as the default but there is a tab for the injectable version too.
 
Last edited:
Omxxl said:
I've had surgery on both knees for meniscus and cruciate ligament tears, in addition to joint degeneration due to cartilage wear. I've been recommended a therapy where they draw blood and inject something like Matrix cells or something similar. They also mentioned peptides like BPC and TB500. I don't know if any of you have tried it and if it has been helpful for this type of cartilage wear injury.
I would greatly appreciate your opinions and experiences, friends.
Click to expand...

I've never had anything as serious as yours, but I know by experience and by much, much anecdotal testimonies and reviews, TB-500 first at 2mg everyday for 3 weeks, then BPC-157 at 1mg everyday for 3 weeks is supposed to help up to 90%. Even more if you do PT/Post recovery activity/non-activity.

I also know that if you're dealing with other conditions like lack of or damaged mitochondria, using SS-31 can dramatically help repair/rebuild/recover metabolic disfunction, mitochondria, reduce oxidative stress and inflammation, so many good things and that could also have a very direct effect on the other peps/compounds you're taking in terms of effectiveness.

I had a right rotator cuff injury for just over a year and after taking that BPC/TB protocol, it's 80% better without PT. With very inconsistent PT sessions 🤣 It's sitting at 90% completely healed!

Clearly you've been working out - I would recommend you check out IGF-1 LR3 and CJC/IPA. They may also be able to help!
 
I had a reoccurring pain in the back of my knee that went on for years. I did a cycle of ghkcu, bpb157 and tb500. The pain was completely gone after 3 or so weeks and hasn't been back since. This was 4-5 years ago.

I dont remember my exact protocol but I believe it was 2.5mg ghkcu daily. 500mcg bpc daily and 2.5mg tb500 2x a week for 8-10 weeks
 
Smiter said:
BPC-157, TB-500, GHK-Cu, Cartalax. Dont buy blends. Inject BPPC near injury site, and TB-500 systemically. I use BPC and TB for my torn rotator cuff and biceps tendinosis. Also, consume 30 grams of collagen peptides daily with hyaluronic acid, vitamin C, and glucosamine and chondroitin.
Click to expand...
I thought that BPC was local was largely disregarded. I used to inject BPC locally by clipping my elbow to get a pin sight (some times I would inadvertently go right through both sides…). Now, I just do like TB in the belly. I personally haven’t notice a difference. But in my view, if you really want to get best out BPC, inject it twice a day. The half life is super short.
 
If only looking at studies, GLP1 medication. According to the newest studies, GLP1 regrows cartilage, a feat previously thought as impossible. This is proven, with minimal side effects. Here a nice video summarizing the facts and studies -
View: https://www.youtube.com/watch?v=JM1he4pHzpw

You can also find the study by searching glp1 cartilage growth on google.

Wish you all the best!
 
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dancs said:
I've never had anything as serious as yours, but I know by experience and by much, much anecdotal testimonies and reviews, TB-500 first at 2mg everyday for 3 weeks, then BPC-157 at 1mg everyday for 3 weeks is supposed to help up to 90%. Even more if you do PT/Post recovery activity/non-activity.
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So you only did that first 3 weeks of TB500 and then switched to BPC for 3 more and then stopped both?
 
domin8brix said:
So you only did that first 3 weeks of TB500 and then switched to BPC for 3 more and then stopped both?
Click to expand...
Yeah, I stopped both ---- I did hear that it's better to maintain at 500mcg of both BPC/TB, but I'm already pinning myself 7 times a day. 😭🤣 My abdomen is jacked; been trying to pin under my armpits and butt cheeks...

EDIT: I do PT once/twice a week to maintain instead ***
 
Omxxl said:
I've had surgery on both knees for meniscus and cruciate ligament tears, in addition to joint degeneration due to cartilage wear. I've been recommended a therapy where they draw blood and inject something like Matrix cells or something similar. They also mentioned peptides like BPC and TB500. I don't know if any of you have tried it and if it has been helpful for this type of cartilage wear injury.
I would greatly appreciate your opinions and experiences, friends.
Click to expand...
You should do a 20 day cycle of Cartalax and true TB4 not tb500. Tb500 is a 7 amino fragment of TB4 which is 43 aminos. You can get TB4 with coa at uther, nexaph or aavant.
If you experience it swelling drink lots of water and do KPV alone not Klow.
 
dancs said:
Yeah, I stopped both ---- I did hear that it's better to maintain at 500mcg of both BPC/TB, but I'm already pinning myself 7 times a day. 😭🤣 My abdomen is jacked; been trying to pin under my armpits and butt cheeks...

EDIT: I do PT once/twice a week to maintain instead ***
Click to expand...
Interesting. I had surgery in Feb and it was a lot more entailed than a typical shoulder, so I am advancing slow as shit. I have been debating trying this to see if it helps at all, and maybe i just should.

How much of each were you doing for that cycle?
 
domin8brix said:
Interesting. I had surgery in Feb and it was a lot more entailed than a typical shoulder, so I am advancing slow as shit. I have been debating trying this to see if it helps at all, and maybe i just should.

How much of each were you doing for that cycle?
Click to expand...
Surgery is more serious than a right rotator cuff injury that needs PT.

I did BPC-157 and TB-500 separately.
First 3 weeks I pinned 2mg of TB-500 everyday.
Next 3 weeks I pinned 1mg of BPC-157 everyday.
I did PT once/twice a week during that time.

Right rotator cuff has improved 90%.

Again, I want to be clear, each case is relative.

I don't know exactly what surgery you've been through but what I do know is BPC/TB DOES make a difference when you use the right dose.

Kirbyzx6 said:
You should do a 20 day cycle of Cartalax and true TB4 not tb500. Tb500 is a 7 amino fragment of TB4 which is 43 aminos. You can get TB4 with coa at uther, nexaph or aavant.
If you experience it swelling drink lots of water and do KPV alone not Klow.
Click to expand...

Lately, I've been doing research on other peps/compounds and saw that Cartalax does help with tissue and cartilage. @domin8brix (thank you @Kirbyzx6 )

I did hear TB4 is the complete amino acid compared to TB-500 as being just a part of it. You'll have to dive deeper and see what's going on.
 
I just started PT a few weeks ago, though I can usually only get in there once maybe twice a week--if they would stay open later or open earlier ffs...

But I might try the TB/BJC cycle and see how it does.
 
dancs said:
Surgery is more serious than a right rotator cuff injury that needs PT.

I did BPC-157 and TB-500 separately.
First 3 weeks I pinned 2mg of TB-500 everyday.
Next 3 weeks I pinned 1mg of BPC-157 everyday.
I did PT once/twice a week during that time.

Right rotator cuff has improved 90%.

Again, I want to be clear, each case is relative.

I don't know exactly what surgery you've been through but what I do know is BPC/TB DOES make a difference when you use the right dose.



Lately, I've been doing research on other peps/compounds and saw that Cartalax does help with tissue and cartilage. @domin8brix (thank you @Kirbyzx6 )

I did hear TB4 is the complete amino acid compared to TB-500 as being just a part of it. You'll have to dive deeper and see what's going on.
Click to expand...
Yes starting true TB4 tomorrow complete with Jank coa that it’s not fragment TB500.
 
General Dosage Protocols


Dosage often depends on whether the goal is chronic maintenance or recovery from an acute injury.


• Standard Therapeutic Dose: Often cited between 300 mcg to 1 mg daily, administered via subcutaneous injection.


• Acute/Loading Phase: Some protocols use a higher dose of 2 mg to 5 mg, injected two to three times per week for the first several weeks.


• Maintenance Phase: After the initial recovery period, users often drop to a maintenance dose of 1 mg to 2 mg per week.


Cycle Length


• Duration: A typical cycle usually lasts 4 to 8 weeks.


• Cycling: Most protocols recommend a "rest period" after 3 months of use (e.g., 3 months on, 1 month off) to prevent desensitization or potential long-term side effects.
 
Kirbyzx6 said:
General Dosage Protocols


Dosage often depends on whether the goal is chronic maintenance or recovery from an acute injury.


• Standard Therapeutic Dose: Often cited between 300 mcg to 1 mg daily, administered via subcutaneous injection.


• Acute/Loading Phase: Some protocols use a higher dose of 2 mg to 5 mg, injected two to three times per week for the first several weeks.


• Maintenance Phase: After the initial recovery period, users often drop to a maintenance dose of 1 mg to 2 mg per week.


Cycle Length


• Duration: A typical cycle usually lasts 4 to 8 weeks.


• Cycling: Most protocols recommend a "rest period" after 3 months of use (e.g., 3 months on, 1 month off) to prevent desensitization or potential long-term side effects.
Click to expand...
@domin8brix Yeah so pretty much the highest dosage effectively immediately. 🤣 🤣 🤣 Thanks again @Kirbyzx6
 
@domin8brix @Kirbyzx6 ThePepLair.com also has TB4 but considering how cheap it is for a US vendor reseller, I'd recommend what Kirby is doing - getting it tested.
 
Kirbyzx6 said:
General Dosage Protocols


Dosage often depends on whether the goal is chronic maintenance or recovery from an acute injury.


• Standard Therapeutic Dose: Often cited between 300 mcg to 1 mg daily, administered via subcutaneous injection.


• Acute/Loading Phase: Some protocols use a higher dose of 2 mg to 5 mg, injected two to three times per week for the first several weeks.


• Maintenance Phase: After the initial recovery period, users often drop to a maintenance dose of 1 mg to 2 mg per week.


Cycle Length


• Duration: A typical cycle usually lasts 4 to 8 weeks.


• Cycling: Most protocols recommend a "rest period" after 3 months of use (e.g., 3 months on, 1 month off) to prevent desensitization or potential long-term side effects.
Click to expand...
Do you inject by the injury, or is it a systemic abdomen shot? Thanks!
 
There is also another study with amazing results: https://www.futura-sciences.com/en/...e-cartilage-and-prevent-osteoarthritis_26231/

By injecting prostaglandin E2, the same hormone used for years to induce births,
blocking 15-PGDH, either into the abdomen or directly into the joint, thinning knee cartilage thickened again across the joint surface.

Critically, the regenerated tissue was hyaline cartilage, also called articular cartilage: the smooth, load bearing tissue that cushions joints like the knees and hips and is the primary target of osteoarthritis. This is not the less functional fibrocartilage sometimes seen in wound repair.

“This gerozyme inhibitor causes a dramatic regeneration of cartilage beyond that reported in response to any other drug or intervention,” said Dr. Bhutani.
Click to expand...
 
I am recovering from ACL and complex meniscus repair surgery. I started taking BPC & TB500 7 weeks post op, and GHKCU 8 weeks post op. MY recovery was going slow as shit before I started pinning, I wish I would have started much sooner.
I currently have a blended solution of BPC+TB (Wolverine) with the GHKcu in a separate vial. I have been taking ~1mg of each twice a day. Next order I will make sure they are all separate in their own vials.
I noticed an a significant change in inflammation within 2 weeks and noticed some other nagging soft tissue injuries improved as well. I inject them in the fatty area of the hip/thigh.

I plan to start using IPA when my current batch of MK677 runs out.
 
cheesecake said:
There is also another study with amazing results: https://www.futura-sciences.com/en/...e-cartilage-and-prevent-osteoarthritis_26231/

By injecting prostaglandin E2, the same hormone used for years to induce births,
blocking 15-PGDH, either into the abdomen or directly into the joint, thinning knee cartilage thickened again across the joint surface.

Critically, the regenerated tissue was hyaline cartilage, also called articular cartilage: the smooth, load bearing tissue that cushions joints like the knees and hips and is the primary target of osteoarthritis. This is not the less functional fibrocartilage sometimes seen in wound repair.
Click to expand...
I have both osteoarthritis and age-related muscle atrophy and Prostaglandin e2 seems to partially reverse both.


As soon as I know how many Mg per Kilo dose for humans I am absolutely willing to experiment on myself, I am sure peptide suppliers will stock it soon just as soon as there is sufficient demand for it.

Also, I would imagine combining that with Cartalax and KLOW would very likely enhance the effects. I really have hope that I will not have to use the S&W retirement plan in 10 years.
 
I already ordered a kit of BPC157 5mg and a kit of TB500, which is actually TB4 since, from what I've read, there's hardly any TB500 available.

I'll keep you updated on how it goes. I'll start the first day with 250 micrograms of both daily and gradually increase to 1 mg of each daily. I'll inject the BPC locally in my knee twice a day and the TB subcutaneously.
 
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